Detection of clinically occult primary tumours in patients with cervical metastases of unknown primary tumours: comparison of three-dimensional THRIVE MRI, two-dimensional spin-echo MRI, and contrast-enhanced CT

2018 ◽  
Vol 73 (4) ◽  
pp. 410.e9-410.e15 ◽  
Author(s):  
M.G. Yoo ◽  
J. Kim ◽  
S. Bae ◽  
S.S. Ahn ◽  
S.J. Ahn ◽  
...  
1993 ◽  
Vol 3 (4) ◽  
pp. 597-602 ◽  
Author(s):  
Richard C. Semelka ◽  
J. Patrick Shoenut ◽  
Cynthia M. Magro ◽  
Mervyn A. Kroeker ◽  
Ross Macmahon ◽  
...  

1995 ◽  
Vol 36 (3) ◽  
pp. 300-306 ◽  
Author(s):  
P. Åkeson ◽  
E.-M. Larsson ◽  
D. T. Kristoffersen ◽  
E. Jonsson ◽  
S. Holtás

The aim was to compare the abilities of contrast-enhanced CT, non-contrast-enhanced MR imaging and contrast-enhanced MR imaging using standard (0.1 mmol/kg b.w.) and high (0.3 mmol/kg b.w.) doses of Gadodiamide injection to detect brain metastases (i.e. blood-brain barrier damage). Sixteen patients with at least 2 metastases found by CT were evaluated by MR imaging using non-contrast-enhanced spin-echo, T1-weighted, T2-weighted sequences, and contrast-enhanced spin-echo T1-weighted sequences at 2 dose levels. Gadodiamide injection was first given at the dose of 0.1 mmol/kg b.w. After imaging, another 0.2 mmol/kg b.w. was given, yielding a cumulative dose of 0.3 mmol/kg b.w. No contrast media-related adverse events were recorded. The images were evaluated openly by one and blindly by 2 investigators and the number of metastases, size, delineation (open study) and diagnostic certainty (blind study) of each individual metastasis noted. High-dose MR imaging showed significantly more and smaller metastases than any other examination, and gave a higher diagnostic certainty. All high-dose images were superior to those with the standard dose MR imaging when compared blindly in pairs. We conclude that spin-echo MR imaging with a high dose of Gadodiamide injection is an efficient way to improve the detection of brain metastases, in particular of small ones.


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