scholarly journals Transcriptional Activation of Placental Growth Factor by the Forkhead/Winged Helix Transcription Factor FoxD1

2003 ◽  
Vol 13 (18) ◽  
pp. 1625-1629 ◽  
Author(s):  
Hong Zhang ◽  
Rachel Palmer ◽  
Xiaobo Gao ◽  
Jordan Kreidberg ◽  
William Gerald ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Growth Factor ◽  
Transcriptional Activation ◽  
Placental Growth Factor ◽  
Winged Helix ◽  
Winged Helix Transcription Factor

scholarly journals Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4

Development ◽  
2003 ◽  
Vol 130 (19) ◽  
pp. 4539-4552 ◽  
Author(s):  
Perry J. Blackshear ◽  
Joan P. Graves ◽  
Deborah J. Stumpo ◽  
Inma Cobos ◽  
John L. R. Rubenstein ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Transcript Variant ◽  
Winged Helix ◽  
Specific Transcript ◽  
Phenotypic Response ◽  
Winged Helix Transcription Factor

scholarly journals The Winged Helix Transcription Factor Foxa3 Regulates Adipocyte Differentiation and Depot-Selective Fat Tissue Expansion

2013 ◽  
Vol 33 (17) ◽  
pp. 3392-3399 ◽  
Author(s):  
Lingyan Xu ◽  
Valentine Panel ◽  
Xinran Ma ◽  
Chen Du ◽  
Lynne Hugendubler ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Adipocyte Differentiation ◽  
Tissue Expansion ◽  
Fat Tissue ◽  
Winged Helix ◽  
Winged Helix Transcription Factor

scholarly journals Nucleosome positioning by the winged helix transcription factor HNF3

1998 ◽  
Vol 12 (1) ◽  
pp. 5-10 ◽  
Author(s):  
E. Y. Shim ◽  
C. Woodcock ◽  
K. S. Zaret
Keyword(s):  
Transcription Factor ◽  
Nucleosome Positioning ◽  
Winged Helix ◽  
Winged Helix Transcription Factor

scholarly journals Crystal Structure of the Virulence Gene Activator AphA fromVibrio choleraeReveals It Is a Novel Member of the Winged Helix Transcription Factor Superfamily

2005 ◽  
Vol 280 (14) ◽  
pp. 13779-13783 ◽  
Author(s):  
Rukman S. De Silva ◽  
Gabriela Kovacikova ◽  
Wei Lin ◽  
Ronald K. Taylor ◽  
Karen Skorupski ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Transcription Factor ◽  
Virulence Gene ◽  
Winged Helix ◽  
Winged Helix Transcription Factor

scholarly journals Positive and Negative Regulation of the Transforming Growth Factor β/Activin Target Gene goosecoid by the TFII-I Family of Transcription Factors

2005 ◽  
Vol 25 (16) ◽  
pp. 7144-7157 ◽  
Author(s):  
Manching Ku ◽  
Sergei Y. Sokol ◽  
Jack Wu ◽  
Maria Isabel Tussie-Luna ◽  
Ananda L. Roy ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Growth Factor ◽  
Transcriptional Activation ◽  
Target Gene ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Related Factor ◽  
P19 Cells ◽  
Binding Factor ◽  
Opposing Effects

ABSTRACT Goosecoid (Gsc) is a homeodomain-containing transcription factor present in a wide variety of vertebrate species and known to regulate formation and patterning of embryos. Here we show that in embryonic carcinoma P19 cells, the transcription factor TFII-I forms a complex with Smad2 upon transforming growth factor β (TGFβ)/activin stimulation, is recruited to the distal element (DE) of the Gsc promoter, and activates Gsc transcription. Downregulation of endogenous TFII-I by small inhibitory RNA in P19 cells abolishes the TGFβ-mediated induction of Gsc. Similarly, Xenopus embryos with endogenous TFII-I expression downregulated by injection of TFII-I-specific antisense oligonucleotides exhibit decreased Gsc expression. Unlike TFII-I, the related factor BEN (binding factor for early enhancer) is constitutively recruited to the distal element in the absence of TGFβ/activin signaling and is replaced by the TFII-I/Smad2 complex upon TGFβ/activin stimulation. Overexpression of BEN in P19 cells represses the TGFβ-mediated transcriptional activation of Gsc. These results suggest a model in which TFII-I family proteins have opposing effects in the regulation of the Gsc gene in response to a TGFβ/activin signal.

The winged-helix transcription factor JUMU regulates development, nucleolus morphology and function, and chromatin organization of Drosophila melanogaster

2010 ◽  
Vol 18 (3) ◽  
pp. 307-324 ◽  
Author(s):  
Annemarie Hofmann ◽  
Madeleine Brünner ◽  
Alexander Schwendemann ◽  
Martin Strödicke ◽  
Sascha Karberg ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Drosophila Melanogaster ◽  
Chromatin Organization ◽  
Winged Helix ◽  
And Function ◽  
Winged Helix Transcription Factor
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