scholarly journals A Xenopus tadpole alternative model to study innate-like T cell-mediated anti-mycobacterial immunity

2019 ◽  
Vol 92 ◽  
pp. 253-259 ◽  
Author(s):  
Rhoo Kun Hyoe ◽  
Jacques Robert
Author(s):  
H. Alasam

The possibility that intrathymic T-cell differentiation involves stem cell-lymphoid interactions in embryos led us to study the ultrastructure of epithelial cell in normal embryonic thymus. Studies in adult thymus showed that it produces several peptides that induce T-cell differentiation. Several of them have been chemically characterized, such as thymosin α 1, thymopoietin, thymic humoral factor or the serum thymic factor. It was suggested that most of these factors are secreted by populations of A and B-epithelial cells.Embryonic materials were obtained from inbred matings of Swiss Albino mice. Thymuses were disected from embryos 17 days old and prepared for transmission electron microscopy. Our studies showed that embryonic thymus at this stage contains undifferentiated and differentiated epithelial cells, large lymphoblasts, medium and few small lymphocytes (Fig. 5). No differences were found between cortical and medullary epithelial cells, in contrast to the findings of Van Vliet et al,. Epithelial cells were mostly of the A-type with low electron density in both cytoplasm and nucleus. However few B-type with high electron density were also found (Fig. 7).


1998 ◽  
Vol 103 (4) ◽  
pp. 1207-1208 ◽  
Author(s):  
Shan-Shun Luo ◽  
Hideto Tamura ◽  
Norio Yokose ◽  
Kiyoyuki Ogata ◽  
Kazuo Dan
Keyword(s):  
T Cell ◽  

1981 ◽  
Vol 117 (9) ◽  
pp. 543-546 ◽  
Author(s):  
J. A. Doyle

1980 ◽  
Vol 116 (4) ◽  
pp. 408-412 ◽  
Author(s):  
E. C. Vonderheid

2001 ◽  
Vol 120 (5) ◽  
pp. A314-A315
Author(s):  
D FRANCHIMONT ◽  
J GALON ◽  
M VACCHIO ◽  
R VISCONTI ◽  
G CHROUSOS ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A523-A523
Author(s):  
A BURICH ◽  
R HERSHBERG ◽  
K WAGGIE ◽  
W ZENG ◽  
J VINEY ◽  
...  

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