Tongue sole (Cynoglossus semilaevis) interleukin 10 receptors are involved in the immune response against bacterial infection

2021 ◽  
Vol 115 ◽  
pp. 103885
Author(s):  
Xue-peng Li ◽  
Jian Zhang
Keyword(s):  
Immune Response ◽  
Bacterial Infection ◽  
Interleukin 10 ◽  
Cynoglossus Semilaevis ◽  
Tongue Sole

Cloning, characterization and functional analysis of dctn5 in immune response of Chinese tongue sole (Cynoglossus semilaevis)

2018 ◽  
Vol 77 ◽  
pp. 392-401 ◽  
Author(s):  
Min Wei ◽  
Wen-teng Xu ◽  
Kun-ming Li ◽  
Ya-dong Chen ◽  
Lei Wang ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Immune Response ◽  
Cynoglossus Semilaevis ◽  
Tongue Sole

scholarly journals Comparative transcriptome profiling of immune response against Vibrio harveyi infection in Chinese tongue sole

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Hao Xu ◽  
Xiwen Xu ◽  
Xihong Li ◽  
Lei Wang ◽  
Jiayu Cheng ◽  
...  
Keyword(s):  
Immune Response ◽  
Molecular Mechanisms ◽  
Vibrio Harveyi ◽  
Bacterial Pathogen ◽  
Transcriptome Profiling ◽  
Transcript Level ◽  
Cynoglossus Semilaevis ◽  
Illumina Hiseq ◽  
Tongue Sole ◽  
And Control

Abstract Vibrio harveyi is a major bacterial pathogen that causes fatal vibriosis in Chinese tongue sole (Cynoglossus semilaevis), resulting in massive mortality in the farming industry. However, the molecular mechanisms of C. semilaevis response to V. harveyi infection are poorly understood. Here, we performed transcriptomic analysis of C. semilaevis, comparing resistant and susceptible families in response to V. harveyi challenge (CsRC and CsSC) and control conditions (CsRU and CsSU). RNA libraries were constructed using 12 RNA samples isolated from three biological replicates of the four groups. We performed transcriptome sequencing on an Illumina HiSeq platform, and generating a total of 1,095 million paired-end reads, with the number of clean reads per library ranging from 75.27 M to 99.97 M. Through pairwise comparisons among the four groups, we identified 713 genes exhibiting significant differences at the transcript level. Furthermore, the expression levels were validated by real-time qPCR. Our results provide a valuable resource and new insights into the immune response to V. harveyi infection.

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