scholarly journals Efficacy of second intra-tendinous platelet-rich-plasma injection in case of incomplete response of the first injection: Three-year follow up experience

2013 ◽  
Vol 94 (9) ◽  
pp. 871-877 ◽  
Author(s):  
B. Dallaudière ◽  
P. Meyer ◽  
V. Hummel ◽  
A. Perozziello ◽  
A. Peuchant ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Incomplete Response ◽  
Plasma Injection

scholarly journals A comparative study of functional outcome between platelet rich plasma injection versus steroid infiltration in plantar fasciitis

2020 ◽  
Vol 6 (2) ◽  
pp. 393
Author(s):  
Harpreet Singh ◽  
Malay P. Gandhi ◽  
Aliasgar J. Rampurwala ◽  
Tej S. Rudani
Keyword(s):  
Comparative Study ◽  
Plantar Fasciitis ◽  
Platelet Rich Plasma ◽  
Corticosteroid Injection ◽  
Injection Group ◽  
Plasma Injection ◽  
Significant Difference ◽  
The Difference ◽  
The Individual

<p class="abstract"><strong>Background:</strong> Plantar fasciitis (PF) is considered as degenerative tendinopathies. Repeated micro trauma is the major etiology of these diseases. Autologous platelet rich plasma (PRP) injections are becoming more popular in the treatment of enthesopathies like PF. The growth factors in PRP cause tissue healing. We compared the result of injecting intra-lesional autologous PRP injections versus steroid infiltration in chronic PF.</p><p class="abstract"><strong>Methods:</strong> A prospective, interventional and analytic comparative study was done and 81 patients (120 heels) were included in this study and were followed up for 6 months. We assessed the outcome of each patient using visual analog score (VAS) and foot and ankle disability index (FADI) on follow-up at 1, 3, and 6 months. <strong></strong></p><p class="abstract"><strong>Results:</strong> In our study, female preponderance was seen. Left side was more common as compared to right side. Unilateral PF is more common than bilateral. The difference with in the individual group at baseline and at 1,3 and 6 months was statistically highly significant in terms of VAS and FADI (p=0.0001) But the difference in the between the two groups was insignificant for VAS and FADI at 1, 3 and 6 months.</p><p class="abstract"><strong>Conclusions:</strong> In our study, as there is no significant difference in VAS and FADI score between corticosteroid injection group and PRP injection group at 1, 3 and 6 months follow up. So, it’s reasonable to conclude that both are equally effective in PF. But as PRP injection comes out to be more time consuming and more costly, corticosteroid seems to be more efficient, cost and time wise. Hence, the latter should be a better choice.      </p>

A Feasibility Study Comparing Platelet-Rich Plasma Injection With Saline for the Treatment of Plantar Fasciitis Using a Prospective, Randomized Trial Design

2018 ◽  
Vol 12 (2) ◽  
pp. 153-158 ◽  
Author(s):  
Sarah Johnson-Lynn ◽  
Alan Cooney ◽  
Diarmaid Ferguson ◽  
Deborah Bunn ◽  
William Gray ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Plantar Fasciitis ◽  
Platelet Rich Plasma ◽  
Resonance Imaging ◽  
Loss To Follow Up ◽  
Plasma Injection ◽  
Level Ii ◽  
Lost To Follow Up ◽  
And Control

Platelet-rich plasma (PRP) has been advocated for treatment of plantar fasciitis but there are few good-quality clinical trials to support its use. We conducted a feasibility study of PRP versus saline for treatment of plantar fasciitis. Patients with 6 months or more of magnetic resonance imaging–proven plantar fasciitis, who had failed conservative treatment were invited to participate in the study. Patients were block randomized to either PRP or an equivalent volume of saline. The techniques used for injection and rehabilitation were standardized for both groups. The patient and assessor were blinded. Visual analogue scale (VAS) for pain and painDETECT score were recorded preoperatively and at 6 months follow-up. From 35 patients approached, 28 (19 female, mean age 50 years) were recruited, with 14 randomized to each arm. At 6 months, 8 patients (28.6%) were lost to follow-up. There was a significant change in VAS score from baseline to follow-up in both intervention (mean change 37.2, P = .008) and control (mean change 42.2, P = .003) groups. There was no correlation between preoperative painDETECT score and change in VAS. Recruitment and loss to follow-up rates were relatively high. Both treatments resulted in a similar, significant, improvement in symptoms. Levels of Evidence: Level II

scholarly journals Functional outcome of platelet rich plasma on lateral epicondylitis of elbow

2017 ◽  
Vol 3 (3) ◽  
pp. 408
Author(s):  
Narayanan V. L. ◽  
Preetha P. ◽  
Maria Joshna J. ◽  
Mishal Dhivya P. J. ◽  
Anbu Selvan
Keyword(s):  
Plasma Treatment ◽  
Conservative Management ◽  
Platelet Rich Plasma ◽  
Lateral Epicondylitis ◽  
Mayo Score ◽  
Plasma Injection ◽  
Before And After ◽  
Elbow Function ◽  
The Mean

<p class="abstract"><strong>Background:</strong> The study was conducted with the aim to explore the efficacy of platelet rich plasma in sixty patients who presented to us with lateral epicondylitis of elbow where conservative management has failed<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> Between 2013 and 2015, 60 patients (M: F- 20: 40) with lateral epicondylitis of elbow were included. All patients presented to us with lateral epicondylitis of elbow where conservative management has failed. All patients are treated with platelet rich plasma injection. Serial follow-up were done at 1, 6 and 12 month.<strong></strong></p><p class="abstract"><strong>Results:</strong> All sixty patients had significant improvement before and after platelet rich plasma injection. The mean VAS score and the Mayo score suggests significant improvement in pain and elbow function following platelet rich plasma treatment<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Platelet rich plasma improves pain and elbow function in patients suffering from lateral epicondylitis where conservative management has failed. Platelet rich plasma treatment may decrease the overall time for healing, and thereby decreasing the overall need for surgical intervention<span lang="EN-IN">.</span></p>

Platelet-rich plasma for the treatment of coccydynia: a case report and review of regenerative medicine for coccydynia

2019 ◽  
Vol 14 (12) ◽  
pp. 1151-1154
Author(s):  
Walter I Sussman ◽  
Mairin A Jerome ◽  
Lisa Foster
Keyword(s):  
Platelet Rich Plasma ◽  
Corticosteroid Injection ◽  
Post Injection ◽  
Ultrasound Guided ◽  
Plasma Injection ◽  
Patient Reported ◽  
Sacral Hiatus ◽  
Practice Patient ◽  
Point Tenderness

Aim: To describe the successful treatment of coccydynia using ultrasound-guided injection of platelet-rich plasma. Setting: Outpatient orthopedic practice. Patient: 17-year-old female with BMI of 42.6. Case description: The patient presented with 6 months of nontraumatic coccygeal pain exacerbated by sitting. Physical exam was significant for point-tenderness over the sacral hiatus and coccyx. A corticosteroid injection around the sacrococcygeal ligament was administered with immediate resolution of her pain following the injection with the anesthetic. The patient reported significant pain relief for 1 week. The superficial sacrococcygeal ligament was then treated with a platelet-rich plasma injection under US guidance. Results: The patient reported a 70% improvement in pain and sitting tolerance at 6 weeks. By 6 months post injection, her pain was 100% resolved, and she remained pain free at the 12-month follow-up. Conclusion: Platelet-rich plasma may be considered as a treatment option in patients with refractory coccydynia.

scholarly journals A STUDY TO EVALUATE THE EFFICACY OF PLATELET RICH PLASMA INJECTION IN PATIENTS OF CHRONIC LATERAL EPICONDYLITIS

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Jitendra Singh Rathore ◽  
Lokpal Singh Bhati ◽  
Devendra Singh Rathore
Keyword(s):  
Platelet Rich Plasma ◽  
Lateral Epicondylitis ◽  
Female Gender ◽  
Male And Female ◽  
Vas Score ◽  
Plasma Injection

Background: To study the platelet rich plasma injection in patients of chronic lateral epicondylitis Methods: This study was carried out prospectively on patients age of 18-70 years of both male and female gender suffering from lateral epicondylitis. Results: In this study we found that before injection almost patients had their VAS score were 8-10. None of the patients has been improved their VAS score to 0 at the 4th week 10.00% patients have been improved their VAS score 0 at the 4th month follow-up. Conclusion: We conclude that PRP injection significantly decrease pain and increased elbow performance at 6 months follow-up Keywords: PRP, Elbow, Modality

Ultrasound-Guided Platelet-Rich Plasma Injection in a Patient with a Plantar Fascia Tear

2017 ◽  
Vol 107 (6) ◽  
pp. 565-567 ◽  
Author(s):  
Gökhan Tuna Öztürk ◽  
Alper Murat Ulaşlı
Keyword(s):  
Female Patient ◽  
Platelet Rich Plasma ◽  
Plantar Fascia ◽  
Heel Pain ◽  
Ultrasound Guided ◽  
Plasma Injection

We report the case of a 40-year-old female patient presenting with resistant heel pain attributable to plantar fascia rupture. She was treated with ultrasound-guided platelet-rich plasma injection, and her pain was decreased. Additionally, ultrasound was useful for diagnosis, intervention and follow-up of the patient.

A Single Platelet-Rich Plasma Injection for Chronic Midsubstance Achilles Tendinopathy

2014 ◽  
Vol 7 (5) ◽  
pp. 372-376 ◽  
Author(s):  
Christopher D. Murawski ◽  
Niall A. Smyth ◽  
Hunter Newman ◽  
John G. Kennedy
Keyword(s):  
Platelet Rich Plasma ◽  
Short Form ◽  
General Health Questionnaire ◽  
Case Series ◽  
Achilles Tendinopathy ◽  
Therapeutic Level ◽  
Retrospective Case ◽  
Plasma Injection ◽  
Open Debridement

The purpose of this study was to evaluate a series of patients undergoing a single platelet-rich plasma (PRP) injection for the treatment of chronic midsubstance Achilles tendinopathy, in whom conservative treatment had failed. Thirty-two patients underwent a single PRP injection for the treatment of chronic midsubstance Achilles tendinopathy and were evaluated at a 6-month final follow-up using the Foot and Ankle Outcome Score and Short Form 12 general health questionnaire. Magnetic resonance imaging was performed on all patients prior to and 6 months after injection. Twenty-five of 32 patients (78%) reported that they were asymptomatic at the 6-month follow-up visit and were able to participate in their respective sports and daily activities. The remaining 7 patients (22%) who reported symptoms that did not improve after 6 months ultimately required surgery. Four patients went on to have an Achilles tendoscopy, while the other 3 had an open debridement via a tendon splitting approach. A retrospective evaluation of patients receiving a single PRP injection for chronic midsubstance Achilles tendinopathy revealed that 78% had experienced clinical improvement and had avoided surgical intervention at 6-month follow-up. Levels of Evidence: Therapeutic, Level IV: Retrospective case series

Platelet-rich plasma to rescue an ulcerated orbital dermal fat graft

2018 ◽  
Vol 29 (6) ◽  
pp. 654-658 ◽  
Author(s):  
Tania Andrea Chaparro Tapias ◽  
Alberto Luis Díaz Díaz ◽  
Roberto Secondi ◽  
Helena Coy Villamil ◽  
Juan Carlos Sánchez España
Keyword(s):  
Platelet Rich Plasma ◽  
Rare Complication ◽  
Treatment Protocol ◽  
Fat Graft ◽  
Subconjunctival Injection ◽  
Epithelial Defect ◽  
Plasma Injection ◽  
Autologous Platelet Rich Plasma ◽  
Artificial Prosthesis

Introduction: Central graft ulceration is a rare complication of an orbital dermal fat graft caused by diminished blood supply to the implant. This study reports on the efficacy and safety of the use of a single subconjunctival injection of autologous platelet-rich plasma to rescue an ulcerated orbital dermal fat graft. Methods: Three patients, who had undergone autologous dermal fat graft to treat their anophthalmic socket, were given a 2-mL subconjunctival platelet-rich plasma injection in the exposed graft margins. Demographic and clinical features, treatment protocol, clinical course, complications and follow-up time are reported. In the preoperative examination, all the patients presented a primary epithelial defect of the dermal fat graft. Results: There were no major complications such as necrosis or infection. One patient presented a small conjunctival granuloma at 1-month follow up. Mean postoperative follow-up duration was 13 (range: 10–16) months. By 1 month, the chronic epithelial defect had resolved with the graft integrated within the orbital tissues in all cases. All patients were referred for artificial prosthesis placement. Conclusion: Although further work is needed, our findings suggest that a single subconjunctival platelet-rich plasma injection could be an effective, safe and economic alternative to surgery to rescue an ulcerated orbital dermal fat graft.

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