Ribavirin long-term treatment for chronic hepatitis E virus infection in a liver transplant recipient

2020 ◽  
Vol 52 (8) ◽  
pp. 926-927 ◽  
Author(s):  
M Casper ◽  
MC Reichert ◽  
J Rissland ◽  
F Grünhage ◽  
F Lammert
2014 ◽  
Vol 52 (12) ◽  
pp. 4425-4427 ◽  
Author(s):  
A. M. Passos-Castilho ◽  
G. Porta ◽  
I. K. Miura ◽  
R. P. S. Pugliese ◽  
V. L. B. Danesi ◽  
...  

Author(s):  
Yunlong Li ◽  
Zhijiang Miao ◽  
Pengfei Li ◽  
Ruyi Zhang ◽  
Denis E. Kainov ◽  
...  

AbstractWe show that ivermectin, an FDA-approved anti-parasitic drug, effectively inhibits infection with hepatitis E virus (HEV) genotypes 1 and 3 in a range of cell culture models, including hepatic and extrahepatic cells. Long-term treatment showed no clear evidence of the development of drug resistance. Gene silencing of importin-α1, a cellular target of ivermectin and a key member of the host nuclear transport complex, inhibited viral replication and largely abolished the anti-HEV effect of ivermectin.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Montserrat Fraga ◽  
Jérôme Gouttenoire ◽  
Roland Sahli ◽  
Haithem Chtioui ◽  
Cristina Marcu ◽  
...  

2013 ◽  
Vol 58 (8) ◽  
pp. 2413-2416 ◽  
Author(s):  
Vinaya C. Maddukuri ◽  
Mark W. Russo ◽  
William A. Ahrens ◽  
Suzanne U. Emerson ◽  
Ronald E. Engle ◽  
...  

2008 ◽  
Vol 14 (4) ◽  
pp. 547-553 ◽  
Author(s):  
Elizabeth B. Haagsma ◽  
Arie P. van den Berg ◽  
Robert J. Porte ◽  
Cornelis A. Benne ◽  
Harry Vennema ◽  
...  

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