P114 - Recovery of drug metabolizing enzyme and transporter gene expression in prolonged cultures of confluent 2D-human hepatocyte cultures

Comprehensive Drug Metabolizing Enzyme and Drug Transporter Gene Expression Analysis and Mechanistic Understanding of Drug Disposition via Targeted Transporter Silencing in a Micro patterned Hepatocyte Co-culture System

10.26226/morressier.57ea3d6ad462b8028d88e8e6 ◽

2016 ◽

Author(s):

Guncha Taneja

Keyword(s):

Gene Expression ◽

Expression Analysis ◽

Culture System ◽

Gene Expression Analysis ◽

Drug Disposition ◽

Drug Transporter ◽

Transporter Gene ◽

Mechanistic Understanding ◽

Abstract 769: Regulation of drug metabolizing enzyme and transporter gene expression by dietary and chemopreventive phytochemicals in breast cancer

10.1158/1538-7445.am2014-769 ◽

2014 ◽

Author(s):

Sudha Kondraganti ◽

Lihua Wang ◽

Weiwu Jiang ◽

Bhagavatula Moorthy

Keyword(s):

Breast Cancer ◽

Gene Expression ◽

Transporter Gene ◽

Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption

PLoS ONE ◽

10.1371/journal.pone.0126113 ◽

2015 ◽

Vol 10 (7) ◽

pp. e0126113 ◽

Cited By ~ 14

Author(s):

Andrew W. Bergen ◽

Martha Michel ◽

Denise Nishita ◽

Ruth Krasnow ◽

Harold S. Javitz ◽

...

Keyword(s):

Cigarette Consumption ◽

Transporter Gene ◽

Nicotine Metabolism ◽

Gene Variation ◽

Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2007.03.032 ◽

2007 ◽

Vol 222 (1) ◽

pp. 42-56 ◽

Cited By ~ 84

Author(s):

Katy M. Olsavsky ◽

Jeanine L. Page ◽

Mary C. Johnson ◽

Helmut Zarbl ◽

Stephen C. Strom ◽

...

Keyword(s):

Gene Expression ◽

Gene Expression Profiling ◽

Cell Lines ◽

Expression Profiling ◽

Human Liver ◽

Hepatoma Cell ◽

Human Hepatocyte ◽

Hepatoma Cell Lines ◽

Hepatocyte Cultures ◽

Primary Human Hepatocyte

WITHDRAWN: Toxicogenomics applied to in vitro toxicology: A cDNA- array based gene expression and protein activity study in human hepatocyte cultures upon treatment with Aroclor 1254

Toxicology in Vitro ◽

10.1016/j.tiv.2005.10.017 ◽

2005 ◽

Author(s):

Jürgen Borlak ◽

Jan Drewes ◽

Kay Hofmann ◽

Andreas Bosio

Keyword(s):

Gene Expression ◽

Cdna Array ◽

Human Hepatocyte ◽

In Vitro Toxicology ◽

Protein Activity ◽

Aroclor 1254 ◽

Hepatocyte Cultures

Induction Profile of Rat Organic Anion Transporting Polypeptide 2 (oatp2) by Prototypical Drug-Metabolizing Enzyme Inducers That Activate Gene Expression through Ligand-Activated Transcription Factor Pathways

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.300.1.206 ◽

2002 ◽

Vol 300 (1) ◽

pp. 206-212 ◽

Cited By ~ 46

Author(s):

Grace L. Guo ◽

Supratim Choudhuri ◽

Curtis D. Klaassen

Keyword(s):

Gene Expression ◽

Transcription Factor ◽

Organic Anion ◽

Organic Anion Transporting Polypeptide ◽

Metabolizing Enzyme ◽

Activate Gene ◽

Enzyme Inducers

Identification of novel genetic variants associated with membrane transporter, drug metabolizing enzyme and nuclear receptor gene expression in whole blood

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2016.10.141 ◽

2017 ◽

Vol 32 (1) ◽

pp. S32

Author(s):

Mikko Neuvonen ◽

Päivi Hirvensalo ◽

Aleksi Tornio ◽

Katriina Tarkiainen ◽

Maria Paile-Hyvärinen ◽

...

Keyword(s):

Gene Expression ◽

Nuclear Receptor ◽

Whole Blood ◽

Genetic Variants ◽

Receptor Gene ◽

Membrane Transporter ◽

Metabolizing Enzyme ◽

Receptor Gene Expression

Xenobiotic-Metabolizing Enzyme and Transporter Gene Expression in Primary Cultures of Human Hepatocytes Modulated by Toxcast Chemicals

Journal of Toxicology and Environmental Health Part B ◽

10.1080/10937404.2010.483949 ◽

2010 ◽

Vol 13 (2-4) ◽

pp. 329-346 ◽

Cited By ~ 45

Author(s):

Daniel M. Rotroff ◽

Andrew L. Beam ◽

David J. Dix ◽

Adam Farmer ◽

Kimberly M. Freeman ◽

...

Keyword(s):

Gene Expression ◽

Primary Cultures ◽

Human Hepatocytes ◽

Transporter Gene ◽

Transcription Factor and Drug-Metabolizing Enzyme Gene Expression in Lymphocytes from Healthy Human Subjects

Drug Metabolism and Disposition ◽

10.1124/dmd.107.017228 ◽

2007 ◽

Vol 36 (1) ◽

pp. 182-189 ◽

Cited By ~ 65

Author(s):

Gérard Siest ◽

Elise Jeannesson ◽

Jean-Brice Marteau ◽

Anastasia Samara ◽

Bérangère Marie ◽

...

Keyword(s):

Gene Expression ◽

Transcription Factor ◽

Human Subjects ◽

Healthy Human ◽

Enzyme Gene ◽

Healthy Human Subjects ◽

Hepatic Xenobiotic Metabolizing Enzyme and Transporter Gene Expression through the Life Stages of the Mouse

PLoS ONE ◽

10.1371/journal.pone.0024381 ◽

2011 ◽

Vol 6 (9) ◽

pp. e24381 ◽

Cited By ~ 25

Author(s):

Janice S. Lee ◽

William O. Ward ◽

Jie Liu ◽

Hongzu Ren ◽

Beena Vallanat ◽

...

Keyword(s):

Gene Expression ◽

Life Stages ◽

Transporter Gene ◽