Changes in illicit drug consumption patterns in 2009 detected by wastewater analysis

2011 ◽  
Vol 118 (2-3) ◽  
pp. 464-469 ◽  
Author(s):  
Ettore Zuccato ◽  
Sara Castiglioni ◽  
Mauro Tettamanti ◽  
Raffaela Olandese ◽  
Renzo Bagnati ◽  
...  
2011 ◽  
Vol 409 (19) ◽  
pp. 3564-3577 ◽  
Author(s):  
Alexander L.N. van Nuijs ◽  
Sara Castiglioni ◽  
Isabela Tarcomnicu ◽  
Cristina Postigo ◽  
Miren Lopez de Alda ◽  
...  

2016 ◽  
Vol 161 ◽  
pp. 178-188 ◽  
Author(s):  
Ettore Zuccato ◽  
Sara Castiglioni ◽  
Ivan Senta ◽  
Andrea Borsotti ◽  
Bruno Genetti ◽  
...  

2017 ◽  
Vol 178 ◽  
pp. 285-290 ◽  
Author(s):  
Ettore Zuccato ◽  
Emma Gracia-Lor ◽  
Nikolaos I. Rousis ◽  
Alberto Parabiaghi ◽  
Ivan Senta ◽  
...  

2014 ◽  
Vol 35 (2) ◽  
pp. 128-132 ◽  
Author(s):  
Sara Castiglioni ◽  
Andrea Borsotti ◽  
Francesco Riva ◽  
Ettore Zuccato

2018 ◽  
Vol 62 ◽  
pp. 139-157 ◽  
Author(s):  
Yusra Bibi Ruhomally ◽  
Nabeelah Banon Jahmeerbaccus ◽  
Muhammad Zaid Dauhoo

We study the NERA model that describes the dynamic evolution of illicit drug usage in a population. The model consists of nonusers (N) and three categories of drug users: the experimental (E) category, the recreational (R) category and the addict (A) category. Two epidemic threshold term known as the reproduction numbers, R0 and μ are defined and derived. Sensitivity analysis of R0 on the parameters are performed in order to determine their relative importance to illicit drug prevalence. The local and global stability of the equilibrium states are also analysed. We also prove that a transcritical bifurcation occurs at R0 = 1. It is shown that an effective campaign of prevention can help to fight against the prevalence of illicit drug consumption. We demonstrate persistence when R0 > 1 and conditions for the extinction of drug consumption are also established. Numerical simulations are performed to verify our model. Our results show that the NERA model can assist policy makers in targeting prevention for maximum effectiveness and can be used to adopt evidence-based policies to better monitor and quantify drug use trends.


2021 ◽  
Author(s):  
ROBERTA ZILLES HAHN ◽  
Marcos Frank Bastiani ◽  
Lilian de Lima Feltraco Lizot ◽  
Anelise Schneider ◽  
Isabela Caroline da Silva Moreira ◽  
...  

2011 ◽  
Vol 26 (S2) ◽  
pp. 123-123
Author(s):  
S. Vucetic-Arsic ◽  
M. Stankovic ◽  
S. Alcaz ◽  
M. Nikic

ObjectiveDuring the last two decades illicit drug use in Belgrade has been changed.Previously, one of the most common methods of illicit heroin use was via intravenous injection. In 1987, injecting drug, as main consumption patterns was accepted by 90,6% of patients, although intravenous administration fell to 75,5% in 1995.The aim of the study was to observe if the main pattern of heroin consumption had changed lately.MethodsThe study included 382 illicit drug users (mean age 28,8 ± 4,7; both gender) treated in Special Hospital for Addiction, Belgrade in period of a year (Sept. 2009–2010).We used data from Pompidou questionnaire and calculated prevalence through standard survey technique.ResultsA total of 94,5% respondents reported a lifetime prevalence of heroin as a main drug, 1,1% of other opiates, 0,3% of cocaine and amphetamine. More than 92,7% of respondents used heroin in the last month regularly. The lifetime prevalence consumption mode for intranasal use was 44,3%, injecting 39,8% and smoking/ inhaling 13,9%.First injectable route experience is reported for age 17–19 = 11.9%; for 20–22 = 25.6%; for 23–26 = 30-3%. The total number of 79,8% reported negative HIV testing result, 0,5% positive result.ConclusionThe consumption model changed in last 10 years and our study confirmed significant diversity. Intranasal administration linked with young population of heroin addicts, who never or rarely use injectable route with low level of HIV infection. Older addicts prefer intravenous use and often change to intranasal route later, for safety or damaged process of peripheral blood vessel.


2017 ◽  
Vol 103 (5) ◽  
pp. F467-F473 ◽  
Author(s):  
Eloise Müller-Schulte ◽  
Gerhard Kurlemann ◽  
Anja Harder

ObjectiveTo determine whether prenatal and perinatal maternal consumption of alcohol, tobacco and/or illicit drugs is associated with risk of neuroblastoma.Data sourcesMedline and Embase (both from inception to February 2017), and reference lists of included studies.Study selectionTo be eligible, a study had to be an original report including data on intake of alcohol, tobacco smoking and/or consumption of illicit drugs during pregnancy and risk of neuroblastoma in the child.Data extractionFrom eligible studies, data study characteristics as well as effect measures and confounders were extracted. We assessed unadjusted and confounder-adjusted estimates, performed risk of bias analysis, constructed random-effects models and assessed heterogeneity.ResultsWe identified 14 case–control studies (1987–2016) involving a total of 3114 children with neuroblastoma. Meta-analysis of unadjusted estimates showed an association between alcohol (OR 1.26; 95% CI 1.07 to 1.49), tobacco (OR 1.22; 95% CI 1.04 to 1.44) and illicit drug consumption during pregnancy and risk of neuroblastoma during childhood, with illicit drug consumption showing the strongest association (OR 3.26; 95% CI 1.36 to 7.86). However, adjusted estimates were highly heterogeneous.LimitationsAll studies were at high risk of bias.ConclusionsSmoking, alcohol or illicit drugs during pregnancy might play a role in the development of neuroblastoma. However, well-designed studies are needed to assess whether these exposures are causal and whether time period during pregnancy, dose or co-consumption of substances is critical.Trial registration numberRegistration number CRD42016036165.


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