Erythrodermic mycosis fungoides treated with low-dose methotrexate and 311 nm UV-B: A case report with 3-year follow up and literature review

Abstract Background Small intestine duplication cysts (SIDCs) are rare congenital anatomical abnormalities of the digestive tract and a rare cause of hematochezia. Case presentation We describe an adult female presented with recurrent hematochezia. The routine gastric endoscope and colonic endoscope showed no positive findings. Abdominal CT scan indicated intussusception due to the "doughnut" sign, but the patient had no typical symptoms. Two subsequent capsule endoscopes revealed a protruding lesion with bleeding in the distal ileum. Surgical resection was performed and revealed a case of SIDC measuring 6 * 2 cm located inside the ileum cavity. The patient remained symptom-free throughout a 7-year follow-up period. Conclusion SIDCs located inside the enteric cavity can easily be misdiagnosed as intussusception by routine radiologic examinations.

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Ameloblastic fibro-odontoma in a child patient: case report and literature review

Research Society and Development ◽

10.33448/rsd-v10i2.12430 ◽

2021 ◽

Vol 10 (2) ◽

pp. e26610212430

Author(s):

Gustavo Zanna Ferreira ◽

Carolina Ferrairo Danieletto-Zanna ◽

Liogi Iwaki Filho ◽

Rômulo Maciel Lustosa ◽

Willian Pecin Jacomacci ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Bone Regeneration ◽

Clinical Characteristics ◽

Patient Case ◽

Lesion Pattern ◽

Local Bone ◽

Ameloblastic Fibroma ◽

Child Patient

The ameloblastic fibro-odontoma (AFO) is a mixed odontogenic tumor, with characteristics of ameloblastic fibroma, presenting enamel and dentin, which occurs more frequently in individuals aged 5 to 17 years. This paper reports na extensive case of ameloblastic fibro-odontoma in the mandible of a 3-year-old patient, discussed in comparison to cases selected from a brief literature review on the clinical characteristics, Evolution and therapeutic options for this lesion. In the last years, there was no consensus in the literature concerning its etiopathogenesis and classification, yet recently the AFO was classified as a developing odontoma. This case is in accordance with the 7 cases reported in the literature of AFO in the mandible of children aged 10 years or younger, especially concerning the lesion pattern and evolution and treatment adopted. The patient did not present relapse and exhibited local bone regeneration at the 3-year follow-up.

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Spinal cord compression in b-thalassemia: follow-up after radiotherapy

Sao Paulo Medical Journal ◽

10.1590/s1516-31801998000600009 ◽

1998 ◽

Vol 116 (6) ◽

pp. 1879-1881 ◽

Cited By ~ 3

Author(s):

Silvana Fahel da Fonseca ◽

Maria Stella Figueiredo ◽

Rodolfo Delfini Cançado ◽

Fernando Nakandakare ◽

Roberto Segreto ◽

...

Keyword(s):

Spinal Cord ◽

Case Report ◽

Spinal Cord Compression ◽

Low Dose ◽

Extramedullary Hematopoiesis ◽

Cord Compression ◽

Hematologic Disorders ◽

Rare Syndrome ◽

Low Dose Radiotherapy

CONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including <FONT FACE="Symbol">b</font>-thalassemia. CASE REPORT: We report the case of a patient with intermediate <FONT FACE="Symbol">b</font>-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. DISCUSSION: Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.

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Laparoscopic Resection of a Giant Dedifferentiated Primary Retroperitoneal Mucinous Cystadenoma (PRMC) in a Young Woman: A Case Report and Literature Review

Journal of Clinical Case Studies ◽

10.16966/2471-4925.215 ◽

2021 ◽

Vol 6 (1) ◽

Author(s):

Wu L ◽

Li X ◽

Li J ◽

Lai Y

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Literature Review ◽

Benign Tumor ◽

Laparoscopic Resection ◽

Abdominal Cavity ◽

Mucinous Cystadenoma ◽

Rare Benign Tumor ◽

Primary Retroperitoneal

Background: PRMC is a very rare benign tumor of the abdominal cavity that usually occurs in women, and PRMC demonstrate no specific findings on CT. There are many reports on the differential diagnosis and discussion of PRMC imaging, but there are few reports on the treatment of dedifferentiated PRMC using laparoscopic resection and postoperative follow-up.

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Low-Dose Methotrexate Could Reduce Severe Early Immune Reactions but Probably Increase Garft Failure in Umbilical Cord Blood Transplantation

Blood ◽

10.1182/blood-2019-131524 ◽

2019 ◽

Vol 134 (Supplement_1) ◽

pp. 5679-5679

Author(s):

Liu Huilan ◽

Xiaoyu Zhu ◽

Kaidi Song ◽

Xiang Wan ◽

Guangyu Sun ◽

...

Keyword(s):

Cord Blood ◽

Graft Versus Host Disease ◽

Low Dose ◽

Cord Blood Transplantation ◽

Immune Reactions ◽

Graft Versus Host ◽

Blood Transplantation ◽

Dose Methotrexate ◽

Gvhd Prophylaxis

Early immune disorders, including preengraftment syndrome (PES)and acute graft-versus-host disease(aGvHD)are problematic in cord blood transplantation (CBT), and optimal prophylaxis has not been established. Here, we prospectively investigated whether intensive GvHD prophylaxis by adding low-dose methotrexate (MTX)at day 3 after CBThas a prognostic impact on CBT. 16 consecutive single-unit CBT recipients treated for high-risk hematologic malignancies (10 cases) and non-malignancies (6 cases) between February 2019 and March 2019. The patients, 6 female and 10 males, had a median age of 9 years (range 4-40) and a median weight of 26 kg (range 14-68). Myeloablative preparative regimen comprised fludarabine, busulfan and cyclophosphamide for malignancies and reduced-intensity-conditioning comprised fludarabine, cyclophosphamide and total-body irradiation (4 Gy) for non-malignancies. Graft-versus-host disease (GvHD) prophylaxis was cyclosporine and mycophenolate mofetil plus MTX 3 mg/m2 on day+3. 14 patients achieved engraftment at a median of day 19 and had more than 95% (complete) donor chimerism on day+14.Two patients without hematopoietic reconstitution were engrafted after a second CBT. PES was characterized by high-grade fever, rash, pulmonary edema, weight gain, liver and renal dysfunction developed on a median of day 8 in 11 of the 16 evaluable patients, including 2 who did not achieve engraftment. The PES patients received intravenous corticosteroid at a median dose of 1 mg/kg/day, and of these, 2 patients were requiredBasiliximab to improve clinical symptoms. Grade I to IV and aGvHD developed in 4 and only 1 patient developed severe aGvHD with Grade Ⅲ. Follow-up so far, one death occurred at day 103 because of pneumonia. 15 patients are alive well at a median follow-up of 135 days (131-163). Adding low-dose MTX at day +3 may be offer one optimal regimen to reduce severe early immune reactions and improve outcomes in CBT. Disclosures No relevant conflicts of interest to declare.

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