Risk factors associated with the development of diabetic kidney disease in Sudanese patients with type 2 diabetes mellitus: A case-control study

Author(s):  
Mazin MT. Shigidi ◽  
Wieam N. Karrar
Author(s):  
Made Krisna Adi Jaya ◽  
Dewa Ayu Swastini ◽  
Baiq Leny Nopitasari ◽  
Putu Rika Veryanti

Background: Diabetic Peripheral Neuropathy (DPN) is a microvascular complication that commonly occurs in people with diabetes mellitus. Geriatrics with type 2 diabetes mellitus is one of the populations most vulnerable to this complication. An epidemiological study states that geriatrics has a 32% greater risk of developing this complication compared to other age groups. There have not been many studies conducted to evaluate the risk factors that influence this DPN complication, so it needs to be done an individual evaluation for the elderly population. Objective: This study aims to explore the risk factors that influence the incidence of DPN in elderly patients with type 2 diabetes mellitus. Methods: A case-control study design was carried out on 70 geriatrics with type 2 diabetes mellitus. The outcome determined was the incidence of DPN to track the cause of DPN exposure retrospectively. Influential risk factors are determined by the Odds Ratio (OR) with a 95% confidence interval (CI). All statistical analyzes were two-tailed, and p-values <0.05 were considered as statistically significant. Results: Seven factors influence the incidence of DPN in the elderly consisting of smoking history (OR=13.1), uncontrolled lipid profile (OR=5.1), non-neuroprotector users (OR=5.6), uncontrolled blood glucose (OR=42.7), history of heart disease (OR=9.0), uncontrolled blood pressure (OR=4.3), and BMI above normal (OR=5.1). Conclusion: Strong recommendation for medical personnel to focus attention on seven significant risk factors affected complications of DPN to reduce its progression or prevent upcoming complications.


Author(s):  
Viresh Nandimath ◽  
Chaithra Swamy ◽  
Santosh Nandimath ◽  
Gajanan Jatti ◽  
Sachin Jadhav

2012 ◽  
Vol 15 (8) ◽  
pp. 1437-1441 ◽  
Author(s):  
Lina Radzevičienė ◽  
Rytas Ostrauskas

AbstractObjectiveType 2 diabetes mellitus appears to involve an interaction between susceptible genetic backgrounds and environmental factors including highly calorific diets. As it is important to identify modifiable risk factors that may help reduce the risk of type 2 diabetes mellitus, the aim of the present study was to determine the association between egg consumption and the risk of type 2 diabetes mellitus.DesignA specifically designed questionnaire was used to collect information on possible risk factors of type 2 diabetes mellitus. The odds ratios and 95 % confidence intervals for type 2 diabetes mellitus were calculated by conditional logistic regression.SettingA case–control study in a Lithuanian out-patient clinic was performed in 2001.SubjectsA total of 234 cases with a newly confirmed diagnosis of type 2 diabetes mellitus and 468 controls free of the disease.ResultsVariables such as BMI, family history of diabetes, cigarette smoking, education, morning exercise and plasma TAG level were retained in multivariate logistic regression models as confounders because their inclusion changed the value of the odds ratio by more than 10 % in any exposure category. After adjustment for possible confounders more than twofold increased risk of type 2 diabetes mellitus was determined for individuals consuming 3–4·9 eggs/week (OR = 2·60; 95 % CI 1·34, 5·08) and threefold increased risk of the disease was determined for individuals consuming ≥5 eggs/week (OR = 3·02; 95 % CI 1·14, 7·98) compared with those eating <1 egg/week.ConclusionsOur data support a possible relationship of egg consumption and increased risk of type 2 diabetes mellitus.


Author(s):  
Onofre Pineda ◽  
Victoria Stepenka ◽  
Alejandra Rivas-Motenegro ◽  
Nelson Villasmil-Hernandez ◽  
Roberto Añez ◽  
...  

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