Serial measures of cardiac performance using tissue Doppler imaging velocity in preterm infants < 29 weeks gestations

2017 ◽  
Vol 108 ◽  
pp. 33-39 ◽  
Author(s):  
Colm R. Breatnach ◽  
Afif EL-Khuffash ◽  
Adam James ◽  
Naomi McCallion ◽  
Orla Franklin
2020 ◽  
Vol 9 ◽  
pp. 204800402092636
Author(s):  
Luca Faconti ◽  
Iain Parsons ◽  
Bushra Farukh ◽  
Ryan McNally ◽  
Lorenzo Nesti ◽  
...  

Objectives Running a marathon has been equivocally associated with acute changes in cardiac performance. First-phase ejection fraction is a novel integrated echocardiographic measure of left ventricular contractility and systo-diastolic coupling which has never been studied in the context of physical activity. The aim of this study was to assess first-phase ejection fraction following recreational marathon running along with standard echocardiographic indices of systolic and diastolic function. Design and participants: Runners (n = 25, 17 males), age (mean ± standard deviation) 39 ± 9 years, were assessed before and immediately after a marathon race which was completed in 4 h, 10 min ± 47 min. Main outcome measures Central hemodynamics were estimated with applanation tonometry; cardiac performance was assessed using standard M-mode two-dimensional Doppler, tissue-doppler imaging and speckle-tracking echocardiography. First-phase ejection fraction was calculated as the percentage change in left ventricular volume from end-diastole to the time of peak aortic blood flow. Results Conventional indices of systolic function and cardiac performance were similar pre- and post-race while aortic systolic blood pressure decreased by 9 ± 8 mmHg ( P < 0.001) and first-phase ejection fraction increased by approximately 48% from 16.3 ± 3.9% to 22.9 ± 2.5% ( P < 0.001). The ratio of left ventricular transmitral Doppler early velocity (E) to tissue-doppler imaging early annular velocity (e′) increased from 5.1 ± 1.8 to 6.2 ± 1.3 ( P < 0.01). Conclusion In recreational marathon runners, there is a marked increase in first-phase ejection fraction after the race despite no other significant change in cardiac performance or conventional measure of systolic function. More detailed physiological studies are required to elucidate the mechanism of this increase.


2016 ◽  
Vol 101 (6) ◽  
pp. F527-F532 ◽  
Author(s):  
Phani Kiran Yajamanyam ◽  
Robert J S Negrine ◽  
Shree Vishna Rasiah ◽  
Javier Zamora ◽  
Andrew K Ewer

2011 ◽  
Vol 70 ◽  
pp. 253-253
Author(s):  
A Lee ◽  
E Nestaas ◽  
K Liestøl ◽  
L Brunvand ◽  
R Lindemann ◽  
...  

2021 ◽  
Vol 10 (10) ◽  
pp. 2211
Author(s):  
Eunice Torres ◽  
Philip T. Levy ◽  
Afif El-Khuffash ◽  
Hongjie Gu ◽  
Aaron Hamvas ◽  
...  

Bronchopulmonary dysplasia (BPD) is characterized by alveolar-capillary simplification and is associated with pulmonary hypertension (PH) in preterm infants. The contribution of left ventricle (LV) disease towards this severe BPD-PH phenotype is not well established. We aimed to describe the longitudinal trajectory of the LV function as measured by tissue Doppler imaging (TDI) and its association with BPD-PH. We retrospectively assessed prospectively acquired clinical and echocardiographic data from 77 preterm infants born between 2011 and 2013. We characterized the LV function by measuring systolic and diastolic myocardial velocities (s’, e’, a’), isovolumetric relaxation time (IVRT), and myocardial performance index with TDI at three time periods from 32 and 36 weeks, postmenstrual age through one year of age. We also measured post systolic motion (PSM), a marker of myocardial dysfunction that results from asynchronous movement of the ventricular walls, and not previously described in preterm infants. Patients were stratified into groups according to BPD severity and the presence of PH and compared over time. Conventional TDI measures of the LV function were similar between groups, but the septal PSM was significantly prolonged over the first year of age in patients with BPD-PH. PSM provides a novel objective way to assess the hemodynamic impact of lung and pulmonary vascular disease severity on LV function in preterm infants with BPD and PH.


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