scholarly journals Restoring the Long Noncoding RNA MEG3 Indicates a Potential Role for JAK-STAT Signaling in Chronic Myeloid Leukemia

EBioMedicine ◽  
2018 ◽  
Vol 35 ◽  
pp. 24
Author(s):  
Thomas L. Olson ◽  
Thomas P. Loughran
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Long Noncoding Rna ◽  
Myeloid Leukemia ◽  
Noncoding Rna ◽  
Potential Role ◽  
Stat Signaling

scholarly journals The Long Noncoding RNA MEG3 and its Target miR-147 Regulate JAK/STAT Pathway in Advanced Chronic Myeloid Leukemia

EBioMedicine ◽  
2018 ◽  
Vol 34 ◽  
pp. 61-75 ◽  
Author(s):  
Zi-ye Li ◽  
Lin Yang ◽  
Xiao-jun Liu ◽  
Xing-zhe Wang ◽  
Yu-xia Pan ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Long Noncoding Rna ◽  
Myeloid Leukemia ◽  
Noncoding Rna ◽  
Stat Pathway

scholarly journals The role of long noncoding RNA HOTAIR in the acquired multidrug resistance to imatinib in chronic myeloid leukemia cells

Hematology ◽  
2016 ◽  
Vol 22 (4) ◽  
pp. 208-216 ◽  
Author(s):  
Haiying Wang ◽  
Qian Li ◽  
Shusen Tang ◽  
Meifang Li ◽  
Anhua Feng ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Chronic Myeloid Leukemia ◽  
Long Noncoding Rna ◽  
Myeloid Leukemia ◽  
Noncoding Rna ◽  
Leukemia Cells

Long noncoding RNA ANRIL as a novel biomarker in human cancer

2020 ◽  
Vol 16 (35) ◽  
pp. 2981-2995
Author(s):  
Ning Lou ◽  
Guohong Liu ◽  
Yunbao Pan
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Cell Cycle Progression ◽  
Potential Role ◽  
Human Cancer ◽  
Cycle Progression ◽  
Diagnosis And Prognosis ◽  
Cancer Types ◽  
Cancer Medicine

The long noncoding RNA ANRIL, located in the human chromosome 9p21 region, has been reported to be involved in tumor progression. ANRIL regulates gene expression via recruiting PRC2 or titrating miRNA; it also participates in signaling pathways. Evidence has indicated that ANRIL is overexpressed in many cancer types and is capable of enhancing cell proliferation and cell cycle progression and inhibiting apoptosis and senescence. ANRIL has the potential to serve as a biomarker for diagnosis and prognosis in cancer. In this article we focus on recent advances in studies of the oncogenic role of ANRIL and its potential role in cancer medicine.

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