Abstract
Background Some studies have suggested that tumor pathology significantly influence freedom from seizures post epilepsy surgery; however, there is no consensus among researchers regarding this issue. This study aims to retrospectively look for different types of tumor- related epilepsy and their outcomes in the first-year post epilepsy surgery among both adults and children. Methods In this hospital-based retrospective study, patients with drug resistant epilepsy due to brain tumor who underwent epilepsy surgery were included. Our patients underwent a thorough presurgical evaluation in an Epilepsy Monitoring Unit (EMU) before deciding to undergo surgical intervention, according to an epilepsy case-management conference. Four outcomes of interest were investigated during the first-year post epilepsy surgery.Results One hundred patients with brain tumors were included in this study (male: female = 3:2); 45 patients were children. Most of the patients (93) had low-grade gliomas or glioneuronal tumors (G/GNT). No significant differences in outcome were observed between sex, age, or histopathological categories. However, during the first year after epilepsy surgery most of the low-grade G/GNT cases showed favorable outcomes of International League Against Epilepsy (ILAE) class 1 and 2 (61.3% and 9.7%, respectively), while high-grade gliomas and meningothelial tumors showed outcomes of ILAE class 1 (40% and 100%, respectively). Conclusions One-year favorable outcome of post epilepsy surgery of different brain tumors have been achieved among both children and adults. Adequate presurgical evaluation in EMU (for long-term video-electroencephalography monitoring) to plan appropriate surgical strategy is advised. Tumor Pathology does not influence seizure outcome one-year post epilepsy surgery.
Uses and Abuses of the Neuropsychological Assessment in the Presurgical Evaluation of Epilepsy Surgery Candidates
