scholarly journals Erratum to “Type D personality and depressive symptoms are independent predictors of impaired health status in chronic heart failure” [European Journal of Heart Failure 10 (2008) 802-810]

2008 ◽  
Vol 10 (9) ◽  
pp. 921-921 ◽  
Author(s):  
Angélique A. Schiffer ◽  
Susanne S. Pedersen ◽  
Jos W. Widdershoven ◽  
Johan Denollet
Author(s):  
Angélique A. Schiffer ◽  
Susanne S. Pedersen ◽  
Jos W. Widdershoven ◽  
Eric H. Hendriks ◽  
Jobst B. Winter ◽  
...  

Background Chronic heart failure (CHF) is a serious condition that is associated with impaired health status and a high prevalence of depressive symptoms. To date, little is known about the determinants of health status and depressive symptoms in CHF. Therefore, the aim of this study was to assess whether Type D personality is associated with impaired health status and increased depressive symptoms in heart failure patients, independent of disease characteristics. Methods Eighty-four patients (63 men and 21 women, mean age=65.9±12.1 years) with systolic CHF completed four questionnaires to assess Type D personality (14-item Type D Personality Scale [DS14]), health status (Minnesota Living with Heart Failure Questionnaire [MLWHFQ]), depressive symptoms (Center for Epidemiological Studies Depression Scale [CES-D]) and mood status (Global Mood Scale [GMS]) when visiting an outpatient heart failure clinic. Information on clinical variables was obtained from patients’ medical records. Results Type D patients were more likely to experience impairment in health status (18/38=47%) as compared to non-Type Ds (11/46=24%), P=0.027. They also more often reported symptoms of depression; namely 18 of 38=47% versus 6 of 46=13%, P=0.001. When controlling for severity and etiology of CHF, age and gender, Type D remained a significant associate of impaired health status [odds ratio (OR) 3.0, 95% confidence interval (CI) 1.12–7.78] and depressive symptoms (OR 6.3, 95% CI 2.08–19.12). Conclusions Type D was associated with impaired health status and increased depressive symptoms in CHF patients. These preliminary findings demonstrate the value of including personality factors in CHF research.


2010 ◽  
Vol 142 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Aline J. Pelle ◽  
Angélique A. Schiffer ◽  
Otto R. Smith ◽  
Jos W. Widdershoven ◽  
Johan Denollet

2009 ◽  
Vol 103 (3) ◽  
pp. 399-404 ◽  
Author(s):  
Johan Denollet ◽  
Angélique A. Schiffer ◽  
Martijn Kwaijtaal ◽  
Herbert Hooijkaas ◽  
Eric H. Hendriks ◽  
...  

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e58370 ◽  
Author(s):  
Nina Kupper ◽  
Aline J. Pelle ◽  
Balázs M. Szabó ◽  
Johan Denollet

2009 ◽  
Vol 117 (4) ◽  
pp. 165-172 ◽  
Author(s):  
Emeline M. Van Craenenbroeck ◽  
Johan Denollet ◽  
Bernard P. Paelinck ◽  
Paul Beckers ◽  
Nadine Possemiers ◽  
...  

The aim of the present study was to assess whether EPC (endothelial progenitor cell) number/function might be an explanatory factor for the observed relationship between Type D personality (a joint tendency towards negative affectivity and social inhibition) and poor cardiovascular prognosis. We also assessed whether the effect of a single exercise bout on EPC number/function was affected by Type D personality. A total of 35 sedentary men with CHF (chronic heart failure; left ventricular ejection fraction ≤45%) underwent CPET (cardiopulmonary exercise testing) and personality assessment with the 14-item Type D scale. CD34+/KDR (kinase insert domain-containing receptor)+ cells were quantified by flow cytometry before and immediately after CPET. Migration of early EPC towards VEGF (vascular endothelial growth factor) and SDF-1α (stromal-cell-derived factor-1α) was investigated. Type D (n=10) and non-Type D (n=25) patients were comparable with regards to demographics, disease severity and Framingham risk factor score. Circulating EPC numbers were reduced by 54% in Type D compared with non-Type D patients (0.084±0.055 and 0.183±0.029% of lymphocytes respectively; P=0.006). Exercise led to a 60% increase in EPC in Type D patients, whereas the EPC number remained unchanged in the non-Type D group (P=0.049). Baseline migratory capacity was related to disease severity, but was not different between Type D and non-Type D patients. Exercise induced a highly significant enhancement of migratory capacity in both groups. In conclusion, reduced EPC numbers might explain the impaired cardiovascular outcome in Type D patients. The larger increase in circulating EPCs observed in these patients suggests that acute exercise elicits a more pronounced stimulus for endothelial repair.


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