Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: An in vitro study

2011 ◽  
Vol 46 (10) ◽  
pp. 4878-4886 ◽  
Author(s):  
Azmat Ali Khan ◽  
Mahboob Alam ◽  
Saba Tufail ◽  
Jamal Mustafa ◽  
Mohammad Owais
2021 ◽  
Vol 0 (0) ◽  
pp. 9-10
Author(s):  
Samy Shaban ◽  
hamza baghi ◽  
Samir Shafek ◽  
nabila zein ◽  
Ismail Aiad ◽  
...  

2019 ◽  
Vol 31 (10) ◽  
pp. 2191-2196 ◽  
Author(s):  
S. Rathinamanivannan ◽  
K. Megha ◽  
Raja Chinnamanayakar ◽  
Ashok Kumar ◽  
M.R. Ezhilarasi

The new series of 1-(4,5-dihydro-5-phenyl-3-diphenylpyrazol-1-yl)butan-1-one derivatives were synthesized by cyclization method using biphenyl chalcone with n-butyric acid and hydrazine hydrate. The synthesized 1-(4,5-dihydro-5-phenyl-3-diphenylpyrazol-1-yl)butan-1-one derivatives chemical structures were confirmed from spectral data such as FT-IR, 1H and 13C NMR. 2-Pyrazoline derivatives were docked with bacterial (1UAG) and breast cancer (1OQA) protein. Based on high binding affinity score, the best compound was subjected to in vitro anticancer activity by MTT assay. Also, antimicrobial activity were studied for synthesized 2-pyrazoline derivatives.


2014 ◽  
Vol 38 (10) ◽  
pp. 4760-4773 ◽  
Author(s):  
Nesrin Korkmaz ◽  
Ahmet Karadağ ◽  
Ali Aydın ◽  
Yusuf Yanar ◽  
İsa Karaman ◽  
...  

Two novel cyanido-complexes having very significant antibacterial, antifungal and anticancer activities in vitro were synthesized and characterized using various techniques.


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