Design, synthesis and biological evaluation of novel indole-benzimidazole hybrids targeting estrogen receptor alpha (ER-α)

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.01.051 ◽

2018 ◽

Vol 146 ◽

pp. 206-219 ◽

Cited By ~ 13

Author(s):

Ramit Singla ◽

Kunj Bihari Gupta ◽

Shishir Upadhyay ◽

Monisha Dhiman ◽

Vikas Jaitak

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Biological Evaluation ◽

Design Synthesis ◽

Receptor Alpha ◽

Synthesis And Biological Evaluation

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Furans with basic side chains: synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)00488-7 ◽

2001 ◽

Vol 11 (18) ◽

pp. 2521-2524 ◽

Cited By ~ 33

Author(s):

Deborah S. Mortensen ◽

Alice L. Rodriguez ◽

Jun Sun ◽

Benita S. Katzenellenbogen ◽

John A. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Biological Evaluation ◽

Side Chains ◽

Receptor Alpha ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Furans with Basic Side Chains: Synthesis and Biological Evaluation of a Novel Series of Antagonists with Selectivity for the Estrogen Receptor Alpha.

ChemInform ◽

10.1002/chin.200206112 ◽

2010 ◽

Vol 33 (6) ◽

pp. no-no

Author(s):

Deborah S. Mortensen ◽

Alice L. Rodriguez ◽

Jun Sun ◽

Benita S. Katzenellenbogen ◽

John A. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Biological Evaluation ◽

Side Chains ◽

Receptor Alpha ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel dual-acting modulators targeting both estrogen receptor α (ERα) and lysine-specific demethylase 1 (LSD1) for treatment of breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112281 ◽

2020 ◽

Vol 195 ◽

pp. 112281

Author(s):

Ming He ◽

Wentao Ning ◽

Zhiye Hu ◽

Jian Huang ◽

Chune Dong ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Estrogen Receptor Α ◽

Biological Evaluation ◽

Design Synthesis ◽

Lysine Specific Demethylase ◽

Synthesis And Biological Evaluation

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Physicochemical Characteristics and Preliminary in Vivo Biological Evaluation of Nanocapsules Loaded with siRNA Targeting Estrogen Receptor Alpha

Biomacromolecules ◽

10.1021/bm800664c ◽

2008 ◽

Vol 9 (10) ◽

pp. 2881-2890 ◽

Cited By ~ 31

Author(s):

Céline Bouclier ◽

Laurence Moine ◽

Hervé Hillaireau ◽

Véronique Marsaud ◽

Elisabeth Connault ◽

...

Keyword(s):

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Physicochemical Characteristics ◽

Biological Evaluation ◽

Receptor Alpha

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Design, Synthesis, And Biological Evaluation of G Protein‐Coupled Estrogen Receptor (GPR30/GPER) Ligands That Contribute to The First Structure‐Activity‐Relationship for The Receptor

The FASEB Journal ◽

10.1096/fasebj.2018.32.1_supplement.830.9 ◽

2018 ◽

Vol 32 (S1) ◽

Author(s):

Chelsea Sondergard ◽

Christopher Arnatt

Keyword(s):

Estrogen Receptor ◽

G Protein ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

G Protein Coupled ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel indole-xanthendione hybrids as selective estrogen receptor modulators

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.11.040 ◽

2018 ◽

Vol 26 (1) ◽

pp. 266-277 ◽

Cited By ~ 8

Author(s):

Ramit Singla ◽

Kunj Bihari Gupta ◽

Shishir Upadhyay ◽

Monisha Dhiman ◽

Vikas Jaitak

Keyword(s):

Estrogen Receptor ◽

Selective Estrogen Receptor Modulators ◽

Biological Evaluation ◽

Design Synthesis ◽

Estrogen Receptor Modulators ◽

Receptor Modulators ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of cyclopropyl analogues of stilbene with raloxifene side chain as subtype-selective ligands for estrogen receptor

Archives of Pharmacal Research ◽

10.1007/s12272-013-0134-2 ◽

2013 ◽

Vol 36 (9) ◽

pp. 1096-1103 ◽

Cited By ~ 8

Author(s):

Hye Lim Yeo ◽

Yoon Sun Song ◽

Jae-Ha Ryu ◽

Hee-Doo Kim

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Side Chain ◽

Design Synthesis ◽

Selective Ligands ◽

Subtype Selective ◽

Synthesis And Biological Evaluation

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Discovery of novel 2H-chromene-3-carbonyl derivatives as selective estrogen receptor degraders (SERDs): Design, synthesis and biological evaluation

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104714 ◽

2021 ◽

Vol 109 ◽

pp. 104714

Author(s):

Xiang Lu ◽

Yu Teng ◽

Xin Lin ◽

Maoxu Xiao ◽

Chenna Liu ◽

...

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Design Synthesis ◽

Carbonyl Derivatives ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of novel 2-methoxyestradiol analogs as dual selective estrogen receptor modulators (SERMs) and antiangiogenic agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.08.016 ◽

2017 ◽

Vol 139 ◽

pp. 390-400 ◽

Cited By ~ 3

Author(s):

Kejing Lao ◽

Yejun Wang ◽

Mingqi Chen ◽

Jingjing Zhang ◽

Qidong You ◽

...

Keyword(s):

Estrogen Receptor ◽

Selective Estrogen Receptor Modulators ◽

Biological Evaluation ◽

Antiangiogenic Agents ◽

Design Synthesis ◽

Estrogen Receptor Modulators ◽

Receptor Modulators ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of 1,4-dihydrothieno[3′,2′:5,6]thiopyrano[4,3-c]pyrazole-3-carboxylic amide derivatives as potential estrogen receptor antagonists

Chinese Chemical Letters ◽

10.1016/j.cclet.2010.10.029 ◽

2011 ◽

Vol 22 (3) ◽

pp. 256-259 ◽

Cited By ~ 4

Author(s):

Rui Sun ◽

Jing Song ◽

Si Jie Liu ◽

Hui Zhao ◽

Chun Li Yan ◽

...

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Amide Derivatives ◽

Estrogen Receptor Antagonists ◽

Synthesis And Biological Evaluation

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