scholarly journals Moving beyond quality control in diagnostic radiology and the role of the clinically qualified medical physicist

2017 ◽  
Vol 41 ◽  
pp. 104-108 ◽  
Author(s):  
H. Delis ◽  
K. Christaki ◽  
B. Healy ◽  
G. Loreti ◽  
G.L. Poli ◽  
...  
10.37206/41 ◽  
1994 ◽  
Author(s):  
Joel E. Gray ◽  
Gary T. Barnes ◽  
Michael J. Bronskill ◽  
Mary F. Fox ◽  
G. Donald Frey ◽  
...  

Plants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 466
Author(s):  
Marie-Christine Carpentier ◽  
Cécile Bousquet-Antonelli ◽  
Rémy Merret

The recent development of high-throughput technologies based on RNA sequencing has allowed a better description of the role of post-transcriptional regulation in gene expression. In particular, the development of degradome approaches based on the capture of 5′monophosphate decay intermediates allows the discovery of a new decay pathway called co-translational mRNA decay. Thanks to these approaches, ribosome dynamics could now be revealed by analysis of 5′P reads accumulation. However, library preparation could be difficult to set-up for non-specialists. Here, we present a fast and efficient 5′P degradome library preparation for Arabidopsis samples. Our protocol was designed without commercial kit and gel purification and can be easily done in one working day. We demonstrated the robustness and the reproducibility of our protocol. Finally, we present the bioinformatic reads-outs necessary to assess library quality control.


1984 ◽  
Vol 40 (3) ◽  
pp. 441-465
Author(s):  
M. Siedband ◽  
S. Balter ◽  
T. Morgan ◽  
L. Brateman ◽  
W. Properzio ◽  
...  

Author(s):  
Xu Zhou ◽  
Xiongjin Chen ◽  
Tingting Hong ◽  
Miaoping Zhang ◽  
Yujie Cai ◽  
...  

AbstractThe tetrapeptide repeat domain 3 (TTC3) gene falls within Down's syndrome (DS) critical region. Cognitive impairment is a common phenotype of DS and Alzheimer’s disease (AD), and overexpression of TTC3 can accelerate cognitive decline, but the specific mechanism is unknown. The TTC3-mediated protein quality control (PQC) mechanism, similar to the PQC system, is divided into three parts: it acts as a cochaperone to assist proteins in folding correctly; it acts as an E3 ubiquitin ligase (E3s) involved in protein degradation processes through the ubiquitin–proteasome system (UPS); and it may also eventually cause autophagy by affecting mitochondrial function. Thus, this article reviews the research progress on the structure, function, and metabolism of TTC3, including the recent research progress on TTC3 in DS and AD; the role of TTC3 in cognitive impairment through PQC in combination with the abovementioned attributes of TTC3; and the potential targets of TTC3 in the treatment of such diseases.


1995 ◽  
Vol 57 (1-4) ◽  
pp. 293-296
Author(s):  
V. Neofotistou ◽  
M. Molfetas ◽  
N. Panagiotakis

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