Primary syphilis in pregnancy mistaken for genital herpes: A preventable cause of congenital syphilis

2017 ◽  
Vol 219 ◽  
pp. 133 ◽  
Author(s):  
Bridie Howe ◽  
Medhat Basta ◽  
Kirsty Foster ◽  
Umo Esen ◽  
Richard Ellis ◽  
...  
Keyword(s):  
Genital Herpes ◽  
Congenital Syphilis ◽  
Primary Syphilis ◽  
In Pregnancy

Syphilis and pregnancy: Review

2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Samaniego Haro VJ ◽  
Keyword(s):  
Pregnant Woman ◽  
Congenital Syphilis ◽  
Neonatal Morbidity ◽  
Sexual Partners ◽  
Cure Rate ◽  
Chronic Complications ◽  
Drug Of Choice ◽  
Recurrent Abortions ◽  
Penicillin Treatment ◽  
In Pregnancy

Syphilis is a disease that has not been eradicated in part due to inadequate management of antibiotic therapy which is selected according to the stage of the disease and to the misuse of the type of penicillin. Treatment of this disease should be done to prevent it´s chronic complications, to avoid infecting sexual partners and the fetus in a pregnant woman. Syphilis in pregnancy causes increase in the rate of recurrent abortions and neonatal morbidity and mortality, that´s the main reason why early detection and treatment without delay is extremely important. Pregnancy alters immunity, so the serological diagnosis can provide false positives, with the use of inverse algorithms these results may decrease, by increasing the sensitivity of the tests. Today, after 69 years since the advent of penicillin, it has become the drug of choice for any stage of syphilis and in pregnant women; if the patient has allergy, desensitization is indicated either orally or intravenously and other antibiotic shouldn´t be used because of the security offered by penicillin in the cure rate and in the reduction of congenital syphilis. Keywords: Syphilis; Pregnancy; Inverse algorithms.

Infections Caused by Spirochetes: Syphilis, Lyme Disease, Leptospirosis

2018 ◽  
Author(s):  
Patrick Duff
Keyword(s):  
Lyme Disease ◽  
Latent Infection ◽  
Congenital Syphilis ◽  
Ixodes Scapularis ◽  
Severe Disease ◽  
Erythema Migrans ◽  
Treponema Pallidum ◽  
Mild Disease ◽  
Drug Of Choice ◽  
In Pregnancy

Syphilis is caused by the spirochete Treponema pallidum. It is classified as primary, secondary, tertiary, and latent infection. If left untreated, syphilis can cause devastating injury to the fetus. The drug of choice for treatment of syphilis in pregnancy is penicillin. Lyme disease is caused by Borrelia burgdorferi and is transmitted by the Ixodes scapularis tick. The principal clinical manifestation of Lyme disease is erythema migrans, but patients may also develop arthritis and cardiac and neurologic abnormalities. Congenital Lyme disease has not been reported. The drug of choice for treatment of Lyme disease in pregnancy is amoxicillin. Leptospirosis is usually acquired from direct contact with urine of infected animals or through contaminated water, soil, or vegetation. Pregnant women with mild disease should be treated with oral amoxicillin. Patients with severe disease should be hospitalized and treated with intravenous penicillin or ampicillin. This review contains 5 figures, 5 tables, and 19 references. Key Words: clinical infection, congenital syphilis, latent infection, leptospirosis, Lyme disease, syphilis

scholarly journals Acyclovir Suppression to Prevent Clinical Recurrences at Delivery After First Episode Genital Herpes in Pregnancy: An Open-Label Trial

2001 ◽  
Vol 9 (2) ◽  
pp. 75-80 ◽  
Author(s):  
L. Laurie Scott ◽  
Lisa M. Hollier ◽  
Donald McIntire ◽  
Pablo J. Sanchez ◽  
Gregory L. Jackson ◽  
...  
Keyword(s):  
Genital Herpes ◽  
First Episode ◽  
Open Label ◽  
Open Label Trial ◽  
In Pregnancy

Managing genital herpes infections in pregnancy.

2007 ◽  
Vol 74 (3) ◽  
pp. 217-224 ◽  
Author(s):  
C. Gardella ◽  
Z. A Brown
Keyword(s):  
Genital Herpes ◽  
In Pregnancy

scholarly journals Retrospective analysis of burden of maternal syphilis and the outcome in the fetus in a tertiary care centre

2018 ◽  
Vol 4 (2) ◽  
pp. 181
Author(s):  
M. Manimegalai ◽  
P. Elangovan ◽  
V.A. Kayalvizhi ◽  
D. Mithra Rangapriya
Keyword(s):  
Congenital Syphilis ◽  
Single Case ◽  
Tertiary Care ◽  
Routine Screening ◽  
Care Centre ◽  
Perinatal Complications ◽  
Tertiary Care Centre ◽  
Maternal Syphilis ◽  
Common Association ◽  
In Pregnancy

<p class="abstract"><strong>Background:</strong> Syphilis in pregnancy has its own significance with regards to the outcome of pregnancy. In the meanwhile, it also reflects the effectiveness of health system in the community.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was carried out in a tertiary care centre in Chennai between January 2014 and July 2015 to determine the seroprevalence of syphilis in pregnant women. A total of 4423 ANC mother attending the hospital were included in the study.<strong></strong></p><p class="abstract"><strong>Results:</strong> Of the 4423 cases studied, 7 cases were found to be positive for RPR accounting to the prevalence of 0.15%. One mother was symptomatic, presenting with condyloma lata. TPHA was positive in 2 cases (28.5%) Most common association was with HIV infection, 2/7 (28.5%). All the RPR positive patients were treated with tablet erythromycin 500 mg qid × 14 days. Epidose for the partner was given. The outcome was uneventful except for one. A single case of congenital syphilis was reported.</p><p class="abstract"><strong>Conclusions:</strong> Though the prevalence of RPR positive in routine screening is less, the outcome of single congenital syphilis is worrisome. To conclude, although the prevalence of syphilis (0.1%) is low, routine screening of asymptomatic ante natal women is recommended to reduce the incidence of congenital syphilis &amp; perinatal complications and it is always better to treat the ANC mothers with syphilis with Penicillin, preferably with a second dose also.</p>

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