Retrospective analysis of burden of maternal syphilis and the outcome in the fetus in a tertiary care centre

Background: Syphilis in pregnancy has its own significance with regards to the outcome of pregnancy. In the meanwhile, it also reflects the effectiveness of health system in the community.Methods: A retrospective study was carried out in a tertiary care centre in Chennai between January 2014 and July 2015 to determine the seroprevalence of syphilis in pregnant women. A total of 4423 ANC mother attending the hospital were included in the study.Results: Of the 4423 cases studied, 7 cases were found to be positive for RPR accounting to the prevalence of 0.15%. One mother was symptomatic, presenting with condyloma lata. TPHA was positive in 2 cases (28.5%) Most common association was with HIV infection, 2/7 (28.5%). All the RPR positive patients were treated with tablet erythromycin 500 mg qid × 14 days. Epidose for the partner was given. The outcome was uneventful except for one. A single case of congenital syphilis was reported.Conclusions: Though the prevalence of RPR positive in routine screening is less, the outcome of single congenital syphilis is worrisome. To conclude, although the prevalence of syphilis (0.1%) is low, routine screening of asymptomatic ante natal women is recommended to reduce the incidence of congenital syphilis & perinatal complications and it is always better to treat the ANC mothers with syphilis with Penicillin, preferably with a second dose also.

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H1N1 in Pregnancy: A Tertiary Care Centre Experience

Journal of Obstetrics and Gynaecology Canada ◽

10.1016/s1701-2163(16)34954-4 ◽

2011 ◽

Vol 33 (7) ◽

pp. 698-704 ◽

Cited By ~ 7

Author(s):

Ann Kinga Malinowski ◽

Allison McGeer ◽

Julie Robertson ◽

Mathew Sermer ◽

Dan Farine ◽

...

Keyword(s):

Tertiary Care ◽

Care Centre ◽

Tertiary Care Centre ◽

In Pregnancy

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Impact of pica in pregnancy over feto maternal outcome at tertiary care centre in central Indian

International Journal of Clinical Obstetrics and Gynaecology ◽

10.33545/gynae.2021.v5.i5b.1018 ◽

2021 ◽

Vol 5 (5) ◽

pp. 72-75

Author(s):

Deepa Kirar ◽

Dr. Varuna Pathak

Keyword(s):

Tertiary Care ◽

Maternal Outcome ◽

Care Centre ◽

Tertiary Care Centre ◽

In Pregnancy

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High proportion of overt diabetes mellitus in pregnancy and missed opportunity for early detection of diabetes at a tertiary care centre in Pakistan

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.36.icon-suppl.1723 ◽

2019 ◽

Vol 36 (ICON-Suppl) ◽

Author(s):

Aisha Syed Wali ◽

Raheela Rafique ◽

Sundus Iftikhar ◽

Rakhshinda Ambreen ◽

Mohammad Yawar Yakoob

Keyword(s):

Diabetes Mellitus ◽

Early Detection ◽

Tertiary Care ◽

Fasting Blood Glucose ◽

Care Centre ◽

Tertiary Care Centre ◽

Family History Of Diabetes ◽

Overt Diabetes ◽

Missed Opportunity ◽

In Pregnancy

Objectives: To determine the frequency of diabetes in pregnancy (DIP), namely pre-gestational, gestational (GDM) and overt diabetes mellitus (DM) in women registered for delivery. Methods: A retrospective chart review of antenatal women registered between January 01 to August 31, 2017 was performed. Gestational age, diagnosis of DIP, glucose levels at diagnosis and other relevant data was extracted. The effect of various fasting blood glucose (FBG) thresholds for diagnosis of DIP was assessed. Results: DIP was diagnosed in 21.8% women (pre-gestational: 2%, GDM: 81.2%, overt DM: 16.8%). In early registrants, 30.2% were detected through screening. However, 55.3% of women registered late. Women with pre-gestational DM were older, had more miscarriages, and greater personal and family history of diabetes versus GDM and overt DM. Raising the diagnostic threshold of FBG from 92 mg/dl to 95 mg/dl missed three women (0.1%) and to 105 mg/dl, missed six women (0.2%). Conclusion: We observed a high proportion of overt DM. In early registrants, almost one third of DIP was diagnosed in the first half of pregnancy, an opportunity missed in late registrants. Altering diagnostic thresholds of DIP affected only a small proportion of women. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1723 How to cite this:Wali AS, Rafique R, Iftikhar S, Ambreen R, Yakoob MY. High proportion of overt diabetes mellitus in pregnancy and missed opportunity for early detection of diabetes at a tertiary care centre in Pakistan. Pak J Med Sci. Special Supplement ICON 2020. 2020;36(1):S38-S43. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1723 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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