Forecasting gastrointestinal precipitation and oral pharmacokinetics of dantrolene in dogs using an in vitro precipitation testing coupled with in silico modeling and simulation

2017 ◽  
Vol 119 ◽  
pp. 107-113 ◽  
Author(s):  
Atsushi Kambayashi ◽  
Jennifer B. Dressman
Keyword(s):  
Modeling And Simulation ◽  
In Silico ◽  
In Silico Modeling ◽  
Oral Pharmacokinetics

scholarly journals In Silico Modeling and Simulation of Bone Biology: A Proposal

2005 ◽  
Vol 20 (7) ◽  
pp. 1079-1084 ◽  
Author(s):  
Nadine A Defranoux ◽  
Cynthia L Stokes ◽  
Daniel L Young ◽  
Arnold J Kahn
Keyword(s):  
Modeling And Simulation ◽  
In Silico ◽  
Bone Biology ◽  
In Silico Modeling

In vitro and in silico modeling of endovascular stroke treatments for acute ischemic stroke

2021 ◽  
pp. 110693
Author(s):  
Giulia Luraghi ◽  
Rachel M. E. Cahalane ◽  
Emma van de Ven ◽  
Serena Overschie ◽  
Frank J. H. Gijsen ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
In Silico ◽  
In Silico Modeling

scholarly journals Continuum Modeling and Simulation in Bone Tissue Engineering

2019 ◽  
Vol 9 (18) ◽  
pp. 3674 ◽  
Author(s):  
Jose A. Sanz-Herrera ◽  
Esther Reina-Romo
Keyword(s):  
Tissue Engineering ◽  
Modeling And Simulation ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
In Silico ◽  
Assessment Tool ◽  
Numerical Models ◽  
Research Perspective

Bone tissue engineering is currently a mature methodology from a research perspective. Moreover, modeling and simulation of involved processes and phenomena in BTE have been proved in a number of papers to be an excellent assessment tool in the stages of design and proof of concept through in-vivo or in-vitro experimentation. In this paper, a review of the most relevant contributions in modeling and simulation, in silico, in BTE applications is conducted. The most popular in silico simulations in BTE are classified into: (i) Mechanics modeling and scaffold design, (ii) transport and flow modeling, and (iii) modeling of physical phenomena. The paper is restricted to the review of the numerical implementation and simulation of continuum theories applied to different processes in BTE, such that molecular dynamics or discrete approaches are out of the scope of the paper. Two main conclusions are drawn at the end of the paper: First, the great potential and advantages that in silico simulation offers in BTE, and second, the need for interdisciplinary collaboration to further validate numerical models developed in BTE.

scholarly journals In vitro and in silico modeling of perfluoroalkyl substances mixture toxicity in an amphibian fibroblast cell line

Chemosphere ◽  
2019 ◽  
Vol 233 ◽  
pp. 25-33 ◽  
Author(s):  
Gary Hoover ◽  
Supratik Kar ◽  
Samuel Guffey ◽  
Jerzy Leszczynski ◽  
Maria S. Sepúlveda
Keyword(s):  
Cell Line ◽  
In Silico ◽  
Mixture Toxicity ◽  
Fibroblast Cell ◽  
Perfluoroalkyl Substances ◽  
Fibroblast Cell Line ◽  
In Silico Modeling

Capsaicin-loaded solid lipid nanoparticles: design, biodistribution, in silico modeling and in vitro cytotoxicity evaluation

2020 ◽  
Vol 32 (9) ◽  
pp. 095101
Author(s):  
Selvaraj Kunjiappan ◽  
Murugesan Sankaranarayanan ◽  
Banoth Karan Kumar ◽  
Parasuraman Pavadai ◽  
Ewa Babkiewicz ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticles ◽  
In Silico ◽  
Lipid Nanoparticles ◽  
In Vitro Cytotoxicity ◽  
Solid Lipid ◽  
In Silico Modeling
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