Anticonvulsant effects of methyl ethyl ketone and diethyl ketone in several types of mouse seizure models

2010 ◽  
Vol 642 (1-3) ◽  
pp. 66-71 ◽  
Author(s):  
Nobuyoshi Hasebe ◽  
Kohji Abe ◽  
Eriko Sugiyama ◽  
Rie Hosoi ◽  
Osamu Inoue
1966 ◽  
Vol 11 (3) ◽  
pp. 331-333 ◽  
Author(s):  
W. J. Privott ◽  
D. R. Paul ◽  
K. R. Jolls ◽  
E. M. Schoenborn

1947 ◽  
Vol 25b (1) ◽  
pp. 70-79 ◽  
Author(s):  
A. C. Neish ◽  
F. J. Macdonald

Optically active 4,5-dimethyl-1,3-dioxacyclopentane derivatives can be easily obtained by condensing levo-2,3-butanediol with aldehydes or ketones in the presence of small amounts of strong acids at ordinary temperatures. Condensations were effected with formaldehyde, acetaldehyde, propionaldehyde, butyraldehyde, isobutyraldehyde, 2-ethylbutyraldehyde, 2-ethylhexaldehyde, benzaldehyde, furfural, acrolein, acetone, methyl ethyl ketone, methyl isobutyl ketone, methyl amyl ketone, diethyl ketone, acetophenone, cyclohexanone, acetoin, and diacetyl. The expected products were obtained, two compounds being formed from diacetyl since one or both carbonyl groups may react. Two compounds were obtained from formaldehyde also; in addition to the expected product (levo-4,5-dimethyl-1,3-dioxacyclopentane), 15 to 20% of levo-6,7-dimethyl-1,3,5-trioxacycloheptane was obtained.


1958 ◽  
Vol 36 (2) ◽  
pp. 400-409 ◽  
Author(s):  
P. Ausloos

The liquid phase photolysis of diethyl ketone has been studied in the temperature range from −35° to 95 °C. The CO quantum yield at 95 °C. was found to be close to unity. At 28 °C. decrease in intensity and addition of heptane led to a substantial increase of the CO and the ethane yields.The methyl ethyl ketone liquid phase photolysis at temperatures between 5° and 75 °C. led to the same observations. Arrhenius plots of RE/RB1/2[K] gave for both compounds a value of 5 kcal./mole.Gas phase studies in the temperature range of 0° to 60 °C. confirmed the low CO quantum yield reported previously and showed evidence for disproportionation and recombination reactions between ethyl and propionyl radicals.


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