Urothelial acetylcholine involvement in ATP-induced contractile responses of the rat urinary bladder

2017 ◽  
Vol 809 ◽  
pp. 253-260 ◽  
Author(s):  
Johanna Stenqvist ◽  
Michael Winder ◽  
Thomas Carlsson ◽  
Patrik Aronsson ◽  
Gunnar Tobin
Keyword(s):  
Urinary Bladder ◽  
Rat Urinary Bladder ◽  
Contractile Responses

THE ROLE OF INTERLEUKIN-6 ON THE CONTRACTILE RESPONSES OF RAT URINARY BLADDER

2006 ◽  
Vol 5 (2) ◽  
pp. 79
Author(s):  
S.C. Myung ◽  
M.Y. Lee ◽  
M.K. Lee ◽  
S.H. Ahn ◽  
T.H. Kim ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Interleukin 6 ◽  
Rat Urinary Bladder ◽  
Contractile Responses

Excitation of rat urinary bladder by coaxial electrodes and by chemical agents

1963 ◽  
Vol 204 (4) ◽  
pp. 727-731 ◽  
Author(s):  
F. G. Carpenter
Keyword(s):  
Urinary Bladder ◽  
Motor Nerve ◽  
Water Pressure ◽  
Rat Urinary Bladder ◽  
Contractile Responses ◽  
Ringer’S Solution ◽  
Chemical Agents ◽  
Site Of Action ◽  
Electrical Pulses ◽  
Electrical Stimuli

Electrical stimulation of an isolated rat urinary bladder in tris buffered Ringer's solution by coaxial electrodes elicits contractile responses amounting to 70–130 cm of water pressure. If the Ringer's solution is replaced by isotonic K2SO4 solution, pressures of 60–110 cm water pressure are developed. Responses elicited by low stimulating frequencies (.5–2.5/sec) and by K2SO4 are potentiated by physostigmine, however, 2 mg/liter atropine throughout the entire frequency range of .5–10/sec is without effect. The stimulating actions of K2SO4 and electrical stimuli are dependent upon the availability of Ca++. Responses to electric stimuli are believed to be mediated by way of cholinergic neural elements, those from K+ by a depolarization of the muscle fibers. To a more limited extent the contractile responses resulting from acetylcholine (ACh) are dependent upon Ca++ and contractures are also produced by ACh in bladders suspended in isotonic K2SO4. Conversely, electrical pulses or K2SO4 are effective stimuli in the presence of quantities of ACh or carbamylcholine sufficient to produce maximal responses. This suggests a different site of action for exogenous ACh as opposed to endogenous mediator released from cholinergic motor nerve terminals during motor nerve stimulation.

scholarly journals The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder

2007 ◽  
Vol 570 (1-3) ◽  
pp. 182-187 ◽  
Author(s):  
Chikashi Saitoh ◽  
Chika Kitada ◽  
Wataru Uchida ◽  
Michael B. Chancellor ◽  
William C. de Groat ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Rat Urinary Bladder ◽  
Contractile Responses

Contribution of Cyclooxygenase-Dependent Mechanisms to Contractile Responses to Donepezil in the Rat Urinary Bladder

Pharmacology ◽  
2010 ◽  
Vol 86 (5-6) ◽  
pp. 281-286
Author(s):  
Naoko Shimizu ◽  
Tsutomu Nakahara ◽  
Yuko Kubota ◽  
Kenji Sakamoto ◽  
Kunio Ishii
Keyword(s):  
Urinary Bladder ◽  
Rat Urinary Bladder ◽  
Contractile Responses

Influence of strip size and location on contractile responses of rat urinary bladder body strips

1995 ◽  
Vol 26 (7) ◽  
pp. 1519-1527 ◽  
Author(s):  
Penelope A. Longhurst ◽  
Robert E. Leggett ◽  
Janice A.K. Briscoe
Keyword(s):  
Urinary Bladder ◽  
Rat Urinary Bladder ◽  
Contractile Responses

947: Chemopreventive Effects of COX-2 Inhibitor and Epidermal Growth Factor (EGF)-Receptor Kinase Inhibitor on Rat Urinary Bladder Tumorigenesis

2004 ◽  
Vol 171 (4S) ◽  
pp. 251-251
Author(s):  
Kazunori Hattori ◽  
Katsuyuki Iida ◽  
Akira Johraku ◽  
Sadamu Tsukamoto ◽  
Taeko Asano ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Urinary Bladder ◽  
Egf Receptor ◽  
Kinase Inhibitor ◽  
Receptor Kinase ◽  
Rat Urinary Bladder ◽  
Epidermal Growth ◽  
Cox 2
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