Converting a batch based high-shear granulation process to a continuous dry granulation process; a demonstration with ketoprofen tablets

2020 ◽  
Vol 151 ◽  
pp. 105381
Author(s):  
Krista Taipale-Kovalainen ◽  
Jarkko Ketolainen ◽  
Ossi Korhonen ◽  
Tuomas Ervasti
Keyword(s):  
High Shear ◽  
Granulation Process ◽  
Dry Granulation

Efficient Global Sensitivity-Based Model Calibration of a High-Shear Wet Granulation Process

2021 ◽  
pp. 116569
Author(s):  
Aaron S. Yeardley ◽  
Stefan Bellinghausen ◽  
Robert Milton ◽  
James D. Litster ◽  
Solomon F. Brown
Keyword(s):  
Model Calibration ◽  
Wet Granulation ◽  
High Shear ◽  
Granulation Process ◽  
Global Sensitivity ◽  
High Shear Wet Granulation

Effects of Process and Design Parameters on Granule Size Distribution in a Continuous High Shear Granulation Process

2017 ◽  
Vol 12 (4) ◽  
pp. 283-295 ◽  
Author(s):  
Wei Meng ◽  
Sarang Oka ◽  
Xue Liu ◽  
Thamer Omer ◽  
Rohit Ramachandran ◽  
...  
Keyword(s):  
Size Distribution ◽  
Granule Size ◽  
Design Parameters ◽  
High Shear ◽  
Granulation Process

scholarly journals Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

RSC Advances ◽  
2017 ◽  
Vol 7 (61) ◽  
pp. 38307-38317 ◽  
Author(s):  
F. Shikata ◽  
S. Kimura ◽  
Y. Hattori ◽  
M. Otsuka
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Wet Granulation ◽  
High Shear ◽  
Monitoring Method ◽  
Granulation Process ◽  
High Shear Wet Granulation ◽  
Granule Properties

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

Effect of high shear granulation process parameters on the production of granola cereal aggregates

2011 ◽  
Vol 110 (4) ◽  
pp. 473-481 ◽  
Author(s):  
Pankaj B. Pathare ◽  
Nursin Baş ◽  
John J. Fitzpatrick ◽  
Kevin Cronin ◽  
Edmond P. Byrne
Keyword(s):  
Process Parameters ◽  
High Shear ◽  
Granulation Process

scholarly journals Scale-Up Studies on High Shear Wet Granulation Process from Mini-Scale to Commercial Scale

2008 ◽  
Vol 56 (10) ◽  
pp. 1431-1435 ◽  
Author(s):  
Shouhei Aikawa ◽  
Naomi Fujita ◽  
Hidetoshi Myojo ◽  
Takashi Hayashi ◽  
Tadatsugu Tanino
Keyword(s):  
Scale Up ◽  
Wet Granulation ◽  
High Shear ◽  
Granulation Process ◽  
Commercial Scale ◽  
High Shear Wet Granulation

In-Line Monitoring of a High-Shear Granulation Process Using the Baseline Shift of Near Infrared Spectra

2017 ◽  
Vol 19 (2) ◽  
pp. 710-718 ◽  
Author(s):  
Atsushi Kuriyama ◽  
Jin Osuga ◽  
Yusuke Hattori ◽  
Makoto Otsuka
Keyword(s):  
Infrared Spectra ◽  
Near Infrared ◽  
High Shear ◽  
Granulation Process ◽  
Near Infrared Spectra ◽  
Baseline Shift
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