Comment on: A meta-analysis of common risk factors associated with the diagnosis of developmental dysplasia of the hip in newborns

2013 ◽  
Vol 82 (1) ◽  
pp. 199
Author(s):  
Marcella de Hundt ◽  
Floortje Vlemmix ◽  
Ben Willem J. Mol ◽  
Marjolein Kok
Keyword(s):  
Risk Factors ◽  
Meta Analysis ◽  
Developmental Dysplasia ◽  
Factors Associated ◽  
Common Risk Factors ◽  
Dysplasia Of The Hip

scholarly journals Efficacy of closed reduction for developmental dysplasia of the hip: midterm outcomes and risk factors associated with treatment failure and avascular necrosis

2020 ◽  
Author(s):  
Ge Zhang ◽  
Ming Li ◽  
Xiangyang Qu ◽  
Yujiang Cao ◽  
Xing Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Avascular Necrosis ◽  
Failure Rate ◽  
Closed Reduction ◽  
Significant Risk ◽  
Developmental Dysplasia ◽  
Secondary Outcome ◽  
Factors Associated ◽  
Related Risk ◽  
Dysplasia Of The Hip

Abstract Background: The purpose of this study was to evaluate the efficacy after closed reduction (CR) in the treatment of developmental dysplasia of the hip (DDH) and investigate risk factors associated with CR failure and avascular necrosis (AVN) occurrence in the follow-ups.Primary and secondary outcome measures: The study retrospectively included 110 patients and 138 hips with DDH diagnosis between February 2012 and November 2015 in our single tertiary medical institution and underwent closed reduction. The failure rate of CR and the underlying risk factors were evaluated. meanwhile, the incidence of AVN and the related risk factors among the successful CR cases were assessed.Results: The overall failure rate of DDH treated by CR in present study was 31.16% (43/138). Risk factors for the CR failure was older age at the time of CR (≥18.35 month), large medical interval before CR (≥35.35 millimeters), and severer dislocation of the affected hip (IDHI grade III and IV). The incidence of AVN was 8.33% (6/72) in the patients with successful CR at last follow-up. No significant risk factors had been established in present study that associated with the AVN occurrence.Conclusions: For the treatment of DDH with CR, patients with younger age might achieve better outcomes, early diagnosis and early treatment might be the key point in the DDH treatment.

scholarly journals Efficacy of closed reduction for developmental dysplasia of the hip: midterm outcomes and risk factors associated with treatment failure and avascular necrosis

2020 ◽  
Author(s):  
Ge Zhang ◽  
Ming Li ◽  
Xiangyang Qu ◽  
Yujiang Cao ◽  
Xing Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Avascular Necrosis ◽  
Failure Rate ◽  
Closed Reduction ◽  
Significant Risk ◽  
Developmental Dysplasia ◽  
Factors Associated ◽  
Related Risk ◽  
Younger Age ◽  
Dysplasia Of The Hip

Abstract Background: The purpose of this study was to evaluate the efficacy after closed reduction (CR) in the treatment of developmental dysplasia of the hip (DDH) and to investigate risk factors associated with CR failure and avascular necrosis (AVN) occurrence in follow-ups. Mehtods: The study retrospectively included 110 patients and 138 hips with DDH diagnosis that underwent closed reduction between February 2012 and November 2015 in our single tertiary medical institution. The failure rate of CR and the underlying risk factors were evaluated. Meanwhile, the incidence of AVN and the related risk factors among the successful CR cases were assessed.Results: The overall failure rate of DDH treated by CR in present study was 31.16% (43/138). Risk factors for the CR failure was older age at the time of CR (≥18.35 month), large medical interval before CR (≥35.35 millimeters), and severer dislocation of the affected hip (IDHI grade III and IV). The incidence of AVN was 8.33% (6/72) in the patients with successful CR at last follow-up. No significant risk factors had been established in present study that associated with the AVN occurrence.Conclusions: For the treatment of DDH with CR, patients with younger age might achieve better outcomes, early diagnosis and early treatment might be the key point in the DDH treatment.

scholarly journals Efficacy of closed reduction for developmental dysplasia of the hip: midterm outcomes and risk factors associated with treatment failure and avascular necrosis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Ge Zhang ◽  
Ming Li ◽  
Xiangyang Qu ◽  
Yujiang Cao ◽  
Xing Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Avascular Necrosis ◽  
Failure Rate ◽  
Closed Reduction ◽  
Significant Risk ◽  
Developmental Dysplasia ◽  
Factors Associated ◽  
Related Risk ◽  
Younger Age ◽  
Dysplasia Of The Hip

Abstract Background The purpose of this study was to evaluate the efficacy of closed reduction (CR) in the treatment of developmental dysplasia of the hip (DDH) and to investigate risk factors associated with CR failure and avascular necrosis (AVN) occurrence in follow-ups. Methods The study retrospectively included 110 patients and 138 hips with DDH diagnosis that underwent closed reduction between February 2012 and November 2015 in our single tertiary medical institution. The failure rate of CR and the underlying risk factors were evaluated. Meanwhile, the incidence of AVN and the related risk factors among the successful CR cases were assessed. Results The overall failure rate of DDH treated by CR in the present study was 31.16% (43/138). Risk factors for the CR failure were older age at the time of CR (≥ 18.35 month), large medical interval before CR (≥ 35.35 mm), and severer dislocation of the affected hip (IDHI grades III and IV). The incidence of AVN was 8.33% (6/72) in patients with successful CR at the last follow-up. No significant risk factors had been established in the present study that associated with the AVN occurrence. Conclusions For the treatment of DDH with CR, patients with younger age might achieve better outcomes; early diagnosis and early treatment might be the key point in the DDH treatment.

Risk factors for developmental dysplasia of the hip: a meta-analysis

2012 ◽  
Vol 165 (1) ◽  
pp. 8-17 ◽  
Author(s):  
M. de Hundt ◽  
F. Vlemmix ◽  
J.M.J. Bais ◽  
E.K. Hutton ◽  
C.J. de Groot ◽  
...  
Keyword(s):  
Risk Factors ◽  
Meta Analysis ◽  
Developmental Dysplasia ◽  
Dysplasia Of The Hip

scholarly journals Efficacy of closed reduction for developmental dysplasia of the hip: midterm outcomes and risk factors associated with treatment failure and avascular necrosis

2020 ◽  
Author(s):  
Ge Zhang ◽  
Ming Li ◽  
Xiangyang Qu ◽  
Yujiang Cao ◽  
Xing Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Avascular Necrosis ◽  
Failure Rate ◽  
Closed Reduction ◽  
Significant Risk ◽  
Developmental Dysplasia ◽  
Factors Associated ◽  
Related Risk ◽  
Younger Age ◽  
Dysplasia Of The Hip

Abstract Background: The purpose of this study was to evaluate the efficacy after closed reduction (CR) in the treatment of developmental dysplasia of the hip (DDH) and to investigate risk factors associated with CR failure and avascular necrosis (AVN) occurrence in follow-ups. Mehtods: The study retrospectively included 110 patients and 138 hips with DDH diagnosis that underwent closed reduction between February 2012 and November 2015 in our single tertiary medical institution. The failure rate of CR and the underlying risk factors were evaluated. Meanwhile, the incidence of AVN and the related risk factors among the successful CR cases were assessed.Results: The overall failure rate of DDH treated by CR in present study was 31.16% (43/138). Risk factors for the CR failure was older age at the time of CR (≥18.35 month), large medical interval before CR (≥35.35 millimeters), and severer dislocation of the affected hip (IDHI grade III and IV). The incidence of AVN was 8.33% (6/72) in the patients with successful CR at last follow-up. No significant risk factors had been established in present study that associated with the AVN occurrence.Conclusions: For the treatment of DDH with CR, patients with younger age might achieve better outcomes, early diagnosis and early treatment might be the key point in the DDH treatment.

scholarly journals The common risk factors for progression and mortality in COVID-19 patients: a meta-analysis

2021 ◽  
Author(s):  
Li Zhang ◽  
Jie Hou ◽  
Fu-Zhe Ma ◽  
Jia Li ◽  
Shuai Xue ◽  
...  
Keyword(s):  
Risk Factors ◽  
Meta Analysis ◽  
Common Risk Factors ◽  
The Common

scholarly journals Systematic Review and Meta-Analysis of the Dose-Response and Risk Factors for Obliteration of Arteriovenous Malformations Following Radiosurgery: An Update Based on the Last 20 Years of Published Clinical Evidence

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Shaoyu Zhu ◽  
N Patrik Brodin ◽  
Madhur K Garg ◽  
Patrick A LaSala ◽  
Wolfgang A Tomé
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Dose Response ◽  
Meta Analysis ◽  
Gamma Knife Radiosurgery ◽  
Lesion Size ◽  
Intracranial Arteriovenous Malformation ◽  
Factors Associated ◽  
Obliteration Rate ◽  
Inverse Variance

ABSTRACT BACKGROUND Intracranial arteriovenous malformation (AVM) is a congenital lesion that can potentially lead to devastating consequences if not treated. Many institutional cohort studies have reported on the outcomes after radiosurgery and factors associated with successful obliteration in the last few decades. OBJECTIVE To quantitatively assess the dose-response relationship and risk factors associated with AVM obliteration using a systematic review and meta-analysis approach. METHODS Data were extracted from reports published within the last 20 yr. The dose-response fit for obliteration as a function of marginal dose was performed using inverse-variance weighting. Risk factors for AVM obliteration were assessed by combining odds ratios from individual studies using inverse-variance weighting. RESULTS The logistic model fit showed a clear association between higher marginal dose and higher rates of obliteration. There appeared to be a difference in the steepness in dose-response when comparing studies with patients treated using Gamma Knife radiosurgery (Elekta), compared to linear accelerators (LINACs), and when stratifying studies based on the size of treated AVMs. In the risk-factor analysis, AVM obliteration rate decreases with larger AVM volume or AVM diameter, higher AVM score or Spetzler-Martin (SM) grade, and prior embolization, and increases with compact AVM nidus. No statistically significant associations were found between obliteration rate and age, sex, prior hemorrhage, prior aneurysm, and location eloquence. CONCLUSION A marginal dose above 18 Gy was generally associated with AVM obliteration rates greater than 60%, although lesion size, AVM score, SM grade, prior embolization, and nidus compactness all have significant impact on AVM obliteration rate.

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