Neo-adjuvant chemotherapy for operable gastric cancer: long term results of the Dutch randomised FAMTX trial

2004 ◽  
Vol 30 (6) ◽  
pp. 643-649 ◽  
Author(s):  
H.H Hartgrink ◽  
C.J.H van de Velde ◽  
H Putter ◽  
I Songun ◽  
M.E.T Tesselaar ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Long Term Results ◽  
Neo Adjuvant Chemotherapy

Prognostic Indicators in Stage IV Surgically Treated Gastric Cancer Patients: A Retrospective Multi-Institutional Study

2018 ◽  
Vol 36 (4) ◽  
pp. 331-339
Author(s):  
Alberto Biondi ◽  
Domenico D’Ugo ◽  
Ferdinando Cananzi ◽  
Stefano Rausei ◽  
Federico Sicoli ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Residual Disease ◽  
Stage Iv ◽  
Long Term Results ◽  
Stage Iv Gastric Cancer ◽  
Short And Long Term ◽  
Gastric Cancer Patients

Introduction: The role of gastric resection in treating metastatic gastric adenocarcinoma is controversial. In the present study, we reviewed the short- and long-term outcomes of stage IV patients undergoing surgery. Methods: A retrospective review was conducted that assessed patients undergoing elective surgery for incurable gastric carcinoma. Short- and long-term results were evaluated. Results: A total of 122 stage IV gastric cancer patients were assessed. Postoperative mortality was 5.7%, and the overall rate of complications was 35.2%. The overall survival rate at 1 and 3 years was 58 and 19% respectively; the median survival was 14 months. Improved survival was observed for the factors age less than 60 years (p = 0.015), site of metastases (p = 0.022), extended lymph node dissection (p = 0.044), absence of residual disease after surgery (p = 0.001), and administration of adjuvant chemotherapy (p = 0.016). Multivariate analysis showed that residual disease and adjuvant chemotherapy were independent prognostic factors. Conclusions: The results of this study suggest that surgery combined with systemic chemotherapy in selected patients with stage IV gastric cancer can improve survival.

W2074 Long-Term Consequences of Neo-Adjuvant Chemotherapy for Oesophago-Gastric Cancer On Gastric Contractility and Innervation

2009 ◽  
Vol 136 (5) ◽  
pp. A-786
Author(s):  
Edmond Z. Sung ◽  
Emma Jarvie ◽  
Sean James ◽  
Vinod S. Menon ◽  
Richard A. Borman ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Long Term Consequences ◽  
Neo Adjuvant Chemotherapy

Neo-Adjuvant chemotherapy for inoperable gastric cancer via local and general delivery routes (FLEP Therapy)

1994 ◽  
pp. 411-413 ◽  
Author(s):  
T. Nakajima ◽  
S. Ishihara ◽  
H. Motohashi ◽  
Y. Kitamura ◽  
Y. Nakajima ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Delivery Routes ◽  
Neo Adjuvant Chemotherapy

scholarly journals Immediate and Long-Term Results of the Spleen-Preserved Operations in the Surgical Treatment of Gastric Cancer

2020 ◽  
Vol 13 (3) ◽  
pp. 227-232
Author(s):  
Marina I. Rogozianskaia ◽  
Alexander Nikolayevich Redkin ◽  
Ivan Petrovich Moshurov
Keyword(s):  
Gastric Cancer ◽  
Surgical Treatment ◽  
Total Gastrectomy ◽  
The Body ◽  
Long Term Results ◽  
D2 Lymphadenectomy ◽  
Spleen Preserving ◽  
Cardiac Region ◽  
Clinically Significant

ntroduction. Currently, total gastrectomy with D2 lymphadenectomy is the standard surgical treatment for proximal gastric cancer at the resectable stages (I-III). The issue of advisability of splenectomy as a component of lymphadenectomy remains a controversial one, especially when the tumor is localized in the region of the body or cardiac region of the stomach.The aim of the study was to compare immediate and long-term outcomes, including the quality of life, between spleen preserving and spleen removing surgeries.Methods. The study included 363 patients with gastric cancer II-III stages, localized in the upper and/or the middle third of the stomach, who underwent surgery at the Voronezh Regional Clinical Oncology Hospital and the Voronezh Clinical Hospital of the Russian Railway-Medicine in 2015-2017. All patients were conditionally divided into 2 groups for comparative retrospective analysis. All patients of the first (experimental or spleen-preserved) group (144 patients) were performed R0 total gastrectomy with D2 lymphadenectomy, including splenic hilar nodes (№ 10,11) removal without splenectomy. Patients of the second (control or splenectomy) group (219 patients) were performed R0 total gastrectomy with D2 lymphadenectomy and prophylactic splenectomy (for splenic hilar nodes removal).Results. The average duration of the operation and the volume of blood loss did not differ in both groups. The incidence of early postoperative surgical complications was lower in the spleen-preserved group. Splenectomy was associated with more severe complications of class 4 and 5 according to the Clavien-Dindo classification. Conclusion. Parameters of the 1- and 3-year overall survival rate did not differ in both groups. The results of the GSRS questionnaire were similar in both groups, excluding reflux-esophageal symptoms scale. The reflux scale demonstrated a statistically and clinically significant advantage of spleen preservation.

scholarly journals Factors influencing the postoperative long-term results of the patients with gastric cancer spreading into the subserosal layer.

1990 ◽  
Vol 23 (8) ◽  
pp. 2039-2044 ◽  
Author(s):  
Hiroshi Habu ◽  
Masashi Kono ◽  
Masao Tani ◽  
Toru Honda ◽  
Fumio Kondo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Long Term Results ◽  
Factors Influencing

Long-Term Results After Intraoperative Radiation Therapy for Gastric Cancer

2008 ◽  
Vol 70 (3) ◽  
pp. 715-721 ◽  
Author(s):  
Oliver Drognitz ◽  
Karl Henne ◽  
Christian Weissenberger ◽  
Gregor Bruggmoser ◽  
Heike Göbel ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Radiation Therapy ◽  
Long Term Results ◽  
Intraoperative Radiation Therapy ◽  
Intraoperative Radiation

Adjuvant chemotherapy enhances long-term survival of patients with advanced gastric cancer following curative resection

1990 ◽  
Vol 45 (3) ◽  
pp. 169-172 ◽  
Author(s):  
Yoshihiko Maehara ◽  
Sunao Moriguchi ◽  
Yoshihisa Sakaguchi ◽  
Yasunori Emi ◽  
Shunji Kohnoe ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Advanced Gastric Cancer ◽  
Curative Resection ◽  
Term Survival ◽  
Long Term Survival
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