Neo-Adjuvant chemotherapy for inoperable gastric cancer via local and general delivery routes (FLEP Therapy)

1994 ◽  
pp. 411-413 ◽  
Author(s):  
T. Nakajima ◽  
S. Ishihara ◽  
H. Motohashi ◽  
Y. Kitamura ◽  
Y. Nakajima ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Delivery Routes ◽  
Neo Adjuvant Chemotherapy

scholarly journals Pre-operative laparoscopic staging of gastric cancer in patients who are candidates for neo-adjuvant chemotherapy: A Cross Sectional Study

2019 ◽  
Vol 10 (1) ◽  
pp. 68-72
Author(s):  
Kourosh Ghanadi ◽  
Hormoz Mahmoudvand ◽  
Ali Bakhtiari ◽  
Mojtaba Gorji ◽  
Nasroallah Moradi-kor ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Predictive Value ◽  
Cancer Staging ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Operative Laparoscopy ◽  
Cross Sectional ◽  
Neo Adjuvant Chemotherapy ◽  
Sensitivity Specificity

AbstractObjectiveThe aim of this study is to evaluate the laparoscopic method in gastric cancer staging before surgery in patients undergoing Neo-adjuvant chemotherapy.MethodsThis was a cross-sectional study on patients with T3-T4 and node positive non-metastatic gastric adenocarcinoma who was candidates for neo-adjuvant chemotherapy. The patients were excluded from the study when they were not in the condition to continue the study. All eligible patients underwent metastases work up by abdominal, pelvic and chest CT scans and then received neo-adjuvant chemotherapy. Pre-operative laparoscopy was performed before definitive surgery. The collected data was analyzed using SPSS software. The statistical significance, sensitivity, specificity and predictive values were calculated from this data.ResultsIn this study, out of 50 patients, 26 (52%) were male. The mean age of the patients was 62.44 ± 12.136 years. Most tumors were located in one-third distal of stomach (21 patients, 42%). The accuracy of the laparoscopic method, to determine the degree of involvement of the lymph nodes, revealed that the method had a sensitivity of 84%, a specificity of 47.62%, a positive likelihood ratio (PLR) of 1.6, a negative likelihood ratio (NLR) of 0.33%, a positive predictive value of 65.62% and a negative predictive value of 71.43%. The accuracy of the laparoscopic method, regarding determining the presence or absence of metastasis, revealed that the method had a sensitivity, specificity, positive predictive value, and a negative predictive value of 100%.ConclusionBased on the evidence of this study, and other studies in this field, it seems that the use of a step-by-step combination methods in gastric cancer staging would be logical. Alone, no singular method would be sufficient in providing the physician with sufficient information to successfully stage the tumor and thus determine the appropriate treatment. Therefore, the combination of methods should be used which, in view of the economic constraints of health systems, would be recommended for high-risk patients for metastasis (N+/ T3-T4), diagnostic pre-operative laparoscopy.

Neo-adjuvant chemotherapy for operable gastric cancer: long term results of the Dutch randomised FAMTX trial

2004 ◽  
Vol 30 (6) ◽  
pp. 643-649 ◽  
Author(s):  
H.H Hartgrink ◽  
C.J.H van de Velde ◽  
H Putter ◽  
I Songun ◽  
M.E.T Tesselaar ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Long Term Results ◽  
Neo Adjuvant Chemotherapy

W2074 Long-Term Consequences of Neo-Adjuvant Chemotherapy for Oesophago-Gastric Cancer On Gastric Contractility and Innervation

2009 ◽  
Vol 136 (5) ◽  
pp. A-786
Author(s):  
Edmond Z. Sung ◽  
Emma Jarvie ◽  
Sean James ◽  
Vinod S. Menon ◽  
Richard A. Borman ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Long Term Consequences ◽  
Neo Adjuvant Chemotherapy

Prognostic indicators in gastric cancer after neo-adjuvant chemotherapy and surgery

2013 ◽  
Vol 39 (9) ◽  
pp. S51
Author(s):  
A. Tufo ◽  
R. Persiani ◽  
A. Biondi ◽  
F.C.M. Cananzi ◽  
F. Sicoli ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Prognostic Indicators ◽  
Neo Adjuvant Chemotherapy

scholarly journals A CASE OF GASTRIC CANCER DEMONSTRATING DIFFERENT RESPONSES TO NEO-ADJUVANT CHEMOTHERAPY BETWEEN ADENOCARCINOMA AND AFP-PRODUCING COMPONENT

2009 ◽  
Vol 70 (7) ◽  
pp. 1992-1996 ◽  
Author(s):  
Tomoyuki WAKAHARA ◽  
Makoto SAKA ◽  
Shinji MORITA ◽  
Norimitsu TANAKA ◽  
Takeo FUKAGAWA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Neo Adjuvant Chemotherapy

scholarly journals Neo-adjuvant chemotherapy followed by surgery and chemotherapy or by surgery and chemoradiotherapy for patients with resectable gastric cancer (CRITICS)

BMC Cancer ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Johan L Dikken ◽  
Johanna W van Sandick ◽  
HA Maurits Swellengrebel ◽  
Pehr A Lind ◽  
Hein Putter ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Resectable Gastric Cancer ◽  
Neo Adjuvant Chemotherapy
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