scholarly journals Human Adipose Tissue-derived Mesenchymal Stem Cells Promote Capillary Formation of Peripheral Blood Outgrowth Endothelial Cells in Autologous Fibrin Gels

2015 ◽  
Vol 49 (6) ◽  
pp. 747
Author(s):  
S. Lau
2015 ◽  
Vol 16 (4) ◽  
Author(s):  
Skadi Lau ◽  
Claudia Schrimpf ◽  
Melanie Klingenberg ◽  
Fabian Helfritz ◽  
Thomas Aper ◽  
...  

AbstractCurrently used synthetic vascular grafts bear a high infection risk due to insufficient microvascularization of the graft wall disabling the infiltration of immune cells. Tissue-engineered grafts with a functional pre-vascularization thus would be desirable. However, autologous tissue sources for capillary forming cells need to be evaluated. Here, peripheral blood outgrowth endothelial cells (PB-OEC) from 17 healthy donors and pericyte-like mesenchymal stem cells derived from adipose tissue (ASC) of 17 patients scheduled for visceral surgery were characterized and investigated regarding their ability to form capillary-like networks in plasma-derived fibrin gels. To obtain proliferating PB-OEC with endothelial cell-specific properties (CD31-, VE-cadherin-expression, ac-LDL uptake and three-dimensional (3D)-tube formation in fibrin gels) both enrichment of CD34


Gut ◽  
2008 ◽  
Vol 58 (4) ◽  
pp. 570-581 ◽  
Author(s):  
H Aurich ◽  
M Sgodda ◽  
P Kaltwasser ◽  
M Vetter ◽  
A Weise ◽  
...  

2007 ◽  
Vol 13 (10) ◽  
pp. 2495-2503 ◽  
Author(s):  
M. Knippenberg ◽  
M.N. Helder ◽  
J.M.A. de Blieck-Hogervorst ◽  
P.I.J.M. Wuisman ◽  
J. Klein-Nulend

Life Sciences ◽  
2020 ◽  
Vol 257 ◽  
pp. 118055
Author(s):  
Neda Mokhberian ◽  
Zohreh Bolandi ◽  
Mohamad Eftekhary ◽  
Seyed Mahmoud Hashemi ◽  
Vahid Jajarmi ◽  
...  

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