Electrochemical detection of microRNA based on SA-PPy/AuNPs nanocomposite with the signal amplification through catalytic hairpin assembly reaction and the spontaneous catalytic reaction of Fe3+/Cu2+

2020 ◽  
Vol 362 ◽  
pp. 137168 ◽  
Author(s):  
Xiangyu Ma ◽  
Kun Qian ◽  
Onome Ejeromedoghene ◽  
Martha Kandawa-Schulz ◽  
Yihong Wang
Keyword(s):  
Electrochemical Detection ◽  
Catalytic Reaction ◽  
Signal Amplification ◽  
Catalytic Hairpin Assembly

Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection

2015 ◽  
Vol 51 (33) ◽  
pp. 7100-7103 ◽  
Author(s):  
Xu Hun ◽  
Guoliang Xie ◽  
Xiliang Luo
Keyword(s):  
Detection Limit ◽  
Electrochemical Detection ◽  
Signal Amplification ◽  
Dna Detection ◽  
Scaling Up ◽  
Redox Cycling ◽  
New Strategy ◽  
Electrochemical Signal ◽  
Catalytic Hairpin Assembly

A new strategy for the electrochemical detection of DNA based on catalytic hairpin assembly combined with nanocatalyst label-based redox cycling reaction signal amplification. A superior detection limit of 0.3 aM toward DNA was achieved.

A label-free and enzyme-free signal amplification strategy for a sensitive RNase H activity assay

Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16149-16153 ◽  
Author(s):  
Chang Yeol Lee ◽  
Hyowon Jang ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Signal Amplification ◽  
Rnase H ◽  
Label Free ◽  
Activity Assay ◽  
G Quadruplex ◽  
Catalytic Hairpin Assembly ◽  
Amplification Strategy

A target-triggered catalytic hairpin assembly with a G-quadruplex specific fluorescent binder, NMM, is employed to develop a novel and sensitive RNase H activity assay.

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