Subacute De Quervain thyroiditis after SARS-CoV-2 infection

BACKGROUND: Thyroiditis is an inflammation of the thyroid gland that can arise due to a variety ofcauses. Subacute thyroiditis or de Quervain thyroiditis is comparatively uncommon with recurrence rateof 5% patients over a 20-year period. It usually presents in the form of epidemics and mostly hasoverlapping symptoms, which leads to misdiagnosis.OBJECTIVE: To study sub-acute thyroiditis with the risks and benefits of treatment and consequencesof non treatment.PATIENTS AND METHODS: The study was conducted on seventy (70) patients who visited forconsultancy during April 2014 to May 2015. Their mean age was 37 years, having 28 male 42 females.Those who presented with symptoms of pain in front of neck, unilateral or bilateral, periodic generalizedbody aches, without having history of high grade fever, were included in the study after taking theirconsent. ESR, TFTs and complete blood picture of those having mildly enlarged or not palpable,painful and tender thyroid were done and recorded. They were divided into various groups for steroidtherapy. The patients were selected randomly.RESULTS: All the seventy patients having symptoms, suggestive of thyrioditis had markedly raisedESR with normal TFTs range and rest of the blood picture, were put on 40-45mg/day with tapering dosefor two to six weeks. Those who were put on six weeks steroid therapy had no recurrence, where asthose with duration less than six weeks time suffered from recurrence of symptoms.CONCLUSION: Subacute thyroditis presented with generalized bodyach and tender thyroid gland withraised ESR, when treated with 40-45mg/day prednisolone therapy for six weeks responded significantly.KEY WORDS: Thyroiditis, Subacute thyroiditis, Erythrocyte sedimentation rate, Steroid therapy.

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Sonoelastography in de Quervain Thyroiditis

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2010-1595 ◽

2011 ◽

Vol 96 (2) ◽

pp. 289-290 ◽

Cited By ~ 16

Author(s):

Marek Ruchala ◽

Ewelina Szczepanek ◽

Jerzy Sowinski

Keyword(s):

De Quervain ◽

De Quervain Thyroiditis

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Subacute Thyroiditis in COVID-19 Patients

European Thyroid Journal ◽

10.1159/000511707 ◽

2020 ◽

pp. 1-3

Author(s):

Saeed Sohrabpour ◽

Farrokh Heidari ◽

Ebrahim Karimi ◽

Reza Ansari ◽

Ardavan Tajdini ◽

...

Keyword(s):

Respiratory Illness ◽

Subacute Thyroiditis ◽

Imaging Data ◽

Endocrine Glands ◽

C Reactive Protein ◽

Reactive Protein ◽

History Of ◽

De Quervain ◽

Novel Coronavirus ◽

De Quervain Thyroiditis

Introduction: Since December 2019, novel coronavirus (COVID-19) infection has been identified as the cause of an outbreak of respiratory illness in Wuhan, China. The classic presentation of COVID-19 infection was described as fever, myalgia, cough, and fatigue. Whether coronavirus can directly attack the endocrine glands is unclear. Objective: Post-viral subacute thyroiditis (SAT, de Quervain thyroiditis) has been reported following other viral infection. A limited number of SAT after COVID-19 infection have been reported up to now. Methods: Here, we reported 6 patients with SAT and positive COVID-19 serology tests. Demographic, clinical, biochemical, and imaging data were presented. Results: In this study, 6 patients (4 women and 2 men) with clinician manifestations and physical examination in favor of SAT were described. Cervical ultrasonography showed bilateral hypoechoic areas in the thyroid gland which was suggestive of SAT. Elevated C-reactive protein, erythrocyte sedimentation rate, free thyroxine, free tri-iodothyronine, and undetectable thyrotropin were found in laboratory evaluations. Both IgM and IgG were positive for COVID-19 infection, but the PCR tests were negative in all patients. Patients had history of working in a COVID center and/or family member hospitalized due to COVID-19 pneumonia. Patients were followed up for 1 month and were treated effectively with steroids. Conclusion: This report may help physicians to identify lesser-known manifestations and complications of COVID-19. Early diagnosis of COVID-19 infection results in the prevention of further transmission.

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Subacute thyroiditis after inactive SARS-CoV-2 vaccine

BMJ Case Reports ◽

10.1136/bcr-2021-244711 ◽

2021 ◽

Vol 14 (10) ◽

pp. e244711

Author(s):

Emre Sedar Saygılı ◽

Ersen Karakilic

Keyword(s):

Case Report ◽

Virus Vaccine ◽

Rare Case ◽

Viral Infections ◽

Subacute Thyroiditis ◽

De Quervain ◽

De Quervain Thyroiditis

Viral infections have often been associated with subacute (De Quervain) thyroiditis. Rare cases of subacute thyroiditis have been reported after vaccines. Various vaccines have been developed with different techniques against SARS-CoV-2. This case report presents a rare case of subacute thyroiditis after the inactive SARS-CoV-2 virus vaccine, CoronaVac.

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