scholarly journals SUB-ACUTE THYROIDITIS: ESR AS DIAGNOSTIC MARKER AND OPTIMUM DURATION OF PREDNISOLONE THERAPY

1969 ◽  
Vol 5 (1) ◽  
pp. 582-585
Author(s):  
ASADULLAH ◽  
MAHID IQBAL ◽  
IZAZ UR RAHMAN ◽  
S.M.NAEEM ◽  
IQBAL AHMAD
Keyword(s):  
Thyroid Gland ◽  
Steroid Therapy ◽  
Subacute Thyroiditis ◽  
Blood Picture ◽  
High Grade Fever ◽  
Prednisolone Therapy ◽  
History Of ◽  
De Quervain ◽  
De Quervain Thyroiditis ◽  
Acute Thyroiditis

BACKGROUND: Thyroiditis is an inflammation of the thyroid gland that can arise due to a variety ofcauses. Subacute thyroiditis or de Quervain thyroiditis is comparatively uncommon with recurrence rateof 5% patients over a 20-year period. It usually presents in the form of epidemics and mostly hasoverlapping symptoms, which leads to misdiagnosis.OBJECTIVE: To study sub-acute thyroiditis with the risks and benefits of treatment and consequencesof non treatment.PATIENTS AND METHODS: The study was conducted on seventy (70) patients who visited forconsultancy during April 2014 to May 2015. Their mean age was 37 years, having 28 male 42 females.Those who presented with symptoms of pain in front of neck, unilateral or bilateral, periodic generalizedbody aches, without having history of high grade fever, were included in the study after taking theirconsent. ESR, TFTs and complete blood picture of those having mildly enlarged or not palpable,painful and tender thyroid were done and recorded. They were divided into various groups for steroidtherapy. The patients were selected randomly.RESULTS: All the seventy patients having symptoms, suggestive of thyrioditis had markedly raisedESR with normal TFTs range and rest of the blood picture, were put on 40-45mg/day with tapering dosefor two to six weeks. Those who were put on six weeks steroid therapy had no recurrence, where asthose with duration less than six weeks time suffered from recurrence of symptoms.CONCLUSION: Subacute thyroditis presented with generalized bodyach and tender thyroid gland withraised ESR, when treated with 40-45mg/day prednisolone therapy for six weeks responded significantly.KEY WORDS: Thyroiditis, Subacute thyroiditis, Erythrocyte sedimentation rate, Steroid therapy.

scholarly journals Subacute Thyroiditis in COVID-19 Patients

2020 ◽  
pp. 1-3
Author(s):  
Saeed Sohrabpour ◽  
Farrokh Heidari ◽  
Ebrahim Karimi ◽  
Reza Ansari ◽  
Ardavan Tajdini ◽  
...  
Keyword(s):  
Respiratory Illness ◽  
Subacute Thyroiditis ◽  
Imaging Data ◽  
Endocrine Glands ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
History Of ◽  
De Quervain ◽  
Novel Coronavirus ◽  
De Quervain Thyroiditis

<b><i>Introduction:</i></b> Since December 2019, novel coronavirus (COVID-19) infection has been identified as the cause of an outbreak of respiratory illness in Wuhan, China. The classic presentation of COVID-19 infection was described as fever, myalgia, cough, and fatigue. Whether coronavirus can directly attack the endocrine glands is unclear. <b><i>Objective:</i></b> Post-viral subacute thyroiditis (SAT, de Quervain thyroiditis) has been reported following other viral infection. A limited number of SAT after COVID-19 infection have been reported up to now. <b><i>Methods:</i></b> Here, we reported 6 patients with SAT and positive COVID-19 serology tests. Demographic, clinical, biochemical, and imaging data were presented. <b><i>Results:</i></b> In this study, 6 patients (4 women and 2 men) with clinician manifestations and physical examination in favor of SAT were described. Cervical ultrasonography showed bilateral hypoechoic areas in the thyroid gland which was suggestive of SAT. Elevated C-reactive protein, erythrocyte sedimentation rate, free thyroxine, free tri-iodothyronine, and undetectable thyrotropin were found in laboratory evaluations. Both IgM and IgG were positive for COVID-19 infection, but the PCR tests were negative in all patients. Patients had history of working in a COVID center and/or family member hospitalized due to COVID-19 pneumonia. Patients were followed up for 1 month and were treated effectively with steroids. <b><i>Conclusion:</i></b> This report may help physicians to identify lesser-known manifestations and complications of COVID-19. Early diagnosis of COVID-19 infection results in the prevention of further transmission.

A Comparison Between Two Imaging Techniques for the Diagnosis of Subacute Thyroiditis (De Quervain Thyroiditis)

2010 ◽  
Vol 35 (11) ◽  
pp. 862-864 ◽  
Author(s):  
Patricio González Espinoza ◽  
Claudio Liberman Guendelman ◽  
Lidya Nieves Quevedo Limón ◽  
Rodrigo Jaimovich Fernández
Keyword(s):  
Imaging Techniques ◽  
Subacute Thyroiditis ◽  
De Quervain ◽  
De Quervain Thyroiditis

scholarly journals Subacute thyroiditis after inactive SARS-CoV-2 vaccine

2021 ◽  
Vol 14 (10) ◽  
pp. e244711
Author(s):  
Emre Sedar Saygılı ◽  
Ersen Karakilic
Keyword(s):  
Case Report ◽  
Virus Vaccine ◽  
Rare Case ◽  
Viral Infections ◽  
Subacute Thyroiditis ◽  
De Quervain ◽  
De Quervain Thyroiditis

Viral infections have often been associated with subacute (De Quervain) thyroiditis. Rare cases of subacute thyroiditis have been reported after vaccines. Various vaccines have been developed with different techniques against SARS-CoV-2. This case report presents a rare case of subacute thyroiditis after the inactive SARS-CoV-2 virus vaccine, CoronaVac.

De Quervain thyroiditis. Corner points of the diagnosis

2014 ◽  
Vol 155 (17) ◽  
pp. 676-680 ◽  
Author(s):  
Roland Oláh ◽  
Péter Hajós ◽  
Zsuzsanna Soós ◽  
Gábor Winkler
Keyword(s):  
Needle Aspiration ◽  
Clinical Feature ◽  
Special Treatment ◽  
Reactive Protein ◽  
Viral Respiratory Infection ◽  
History Of ◽  
De Quervain ◽  
Needle Aspiration Cytology ◽  
Destructive Inflammation ◽  
De Quervain Thyroiditis

Inflammatory disorders of the thyroid gland are divided into three groups according to their duration (acute, subacute and chronic). De Quervain’s thyroiditis (also termed giant cell or granulomatous thyroiditis) is a subacute inflammation of the thyroid, which accounts for 5% of thyroid disorders. The etiology is unknown, it usually appears two weeks after an upper viral respiratory infection. The clinical feature includes neck pain, which is aggraviated during swallowing, and radiates to the ear. On palpation, the thyroid is exquisitely tender. The erythrocyte sedimentation rate is markedly elevated, the leukocyte count, C-reactive protein are normal or slightly elevated. The natural history of granulomatous thyroiditis involves four phases: the destructive inflammation results temporarily in hyperthyroidism followed by euthyroidism. After a transient hypothyroidism the disease becomes inactive and the thyroid function is normalised. Ultrasonographic findings are diffuse hypoechogenic structures, but nodules may also occur. The disease often remains unrecognised, or the first phase of the disease is diagnosed and treated as hyperthyroidism. The diagnosis can be confirmed by the presence of the thyroid autoantibodies, radioiodine uptake and fine needle aspiration cytology. There is no special treatment, non-steroid anti-inflammatory drugs or steroid should be given to relieve the pain. The aim of the authors is to shed light the key points of diagnosis and differential diagnosis by the presentation of four slightly different cases. Orv. Hetil., 2014, 155(17), 676–680.

EPIDEMIC THYROIDITIS

1964 ◽  
Vol 45 (3) ◽  
pp. 381-401 ◽  
Author(s):  
G. Hintze ◽  
P. Fortelius ◽  
J. Railo
Keyword(s):  
Thyroid Gland ◽  
Distribution Pattern ◽  
Needle Biopsy ◽  
Serum Proteins ◽  
Acute Infection ◽  
Thyroid Tissue ◽  
Subacute Thyroiditis ◽  
Present Observation ◽  
Upper Respiratory Tract ◽  
Endemic Goitre

ABSTRACT A type of subacute thyroiditis occurring epidemically in a factory in Helsinki was observed in 44 cases. In every case the thyroiditis followed an acute infection of the upper respiratory tract. The variation in incidence during one and a half years was in good agreement with that of the acute infection. Since Helsinki is in an endemic goitre region, the fact that the disease was of the migrating type was of great diagnostic importance. In all cases but one, the nodules have persisted. One case of asymptomatic thyroiditis was seen. In the majority of the patients the thyroid gland had been carefully palpated before the thyroiditis occurred, and in all cases the condition was followed up by the same investigator. Special attention was paid to changes in the iodine metabolism, the serum cholesterol, the electrophoretic distribution pattern of the serum proteins, and the circulating thyroid auto-antibodies. In many cases needle biopsy of the thyroid gland was performed. Thyroid function invariably returned to normal with time, although one patient remained in a hypothyroid state for about a year. In no cases were thyroid auto-antibodies found. For the beta-globulin fraction, the electrophoretic distribution pattern of the serum proteins gave values which were still not normalized in any case, and only in two cases was the alpha2-fraction normalized. The needle biopsy, when thyroid tissue was obtained, showed almost the same picture as in endemic goitre, but in some specimens nonspecific inflammatory changes were seen. Prednisolone relieved the symptoms, but did not affect the course of the disease. According to the present observation this type of epidemic thyroiditis would seem to represent a form of nonspecific subacute thyroiditis.

scholarly journals Melioidosis: A Rare Cause of Liver Abscess

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Peter Franz M. San Martin ◽  
Catherine S. C. Teh ◽  
Ma. Amornetta J. Casupang
Keyword(s):  
Liver Abscess ◽  
Burkholderia Pseudomallei ◽  
Abdominal Ultrasound ◽  
Open Drainage ◽  
High Grade Fever ◽  
Rare Presentation ◽  
Culture Studies ◽  
Moderate Growth ◽  
Male Farmer ◽  
History Of

Case Presentation. This is a case of a 44-year-old male, farmer, known to be diabetic, presenting with two-week history of vague abdominal pain associated with high grade fever. Abdominal CT scan showed localized liver abscess at segment 8 measuring 7.5 × 6.8 × 6.1 cm. Patient subsequently underwent laparoscopic ultrasound guided pigtail insertion for drainage of abscess. Culture studies showed moderate growth ofBurkholderia pseudomalleiin which the patient completed seven days of IV Meropenem. On follow-up after 12 weeks of oral Sulfamethoxazole/Trimethoprim, taken twice a day, the patient remained asymptomatic with no residual findings based on the abdominal ultrasound.Discussion. Diagnosis of melioidosis, a known “great masquerader,” relies heavily on culture studies. Consensus with regard to the management of liver abscess caused byBurkholderia pseudomalleihas not yet been established due to the rarity of cases. Surgical intervention through either a percutaneous or open drainage has shown good outcomes compared to IV antibiotics alone. In Philippines, the possibility of underreporting is highly plausible. This write-up serves not only to report a rare presentation of melioidosis but also to add to the number of cases reported in the country, possibly indicative of disease emergence.

About acute non-suppurative thyroiditis  

1930 ◽  
Vol 26 (1) ◽  
pp. 52-56
Author(s):  
M. M. Lyakhovitsky  
Keyword(s):  
Thyroid Gland ◽  
Rare Diseases ◽  
Acute Inflammation ◽  
Thymus Gland ◽  
Suppurative Thyroiditis ◽  
The Difference ◽  
Acute Thyroiditis ◽  
Number Of Authors

Acute thyroiditis, especially non-purulent, are very rare diseases. The first works devoted to the description of acute inflammation of the thyroid gland date back to the beginning of the last century. In the works of a number of authors (Conradi, W eitenwebe.r'a, Bauchet'a, Pi II c hod), the essence of this disease has already been successfully clarified and the difference between thyroiditis inflammation of a healthy thyroid gland and strumite inflammation of the thymus gland is firmly established. In the process of further study of this issue, a number of works appeared (Lcbert'a, Kocher'a, Mygind'a, etc.), in which, along with elucidation of a number of etiological moments that cause this disease, and a description of the pathological anatomical picture, were questioned and even the existence of primary non-suppurative thyroiditis was denied.

Acute thyroiditis after tooth extraction

1935 ◽  
Vol 31 (3-4) ◽  
pp. 535-535
Author(s):  
E. Auslender
Keyword(s):  
Thyroid Gland ◽  
Tooth Extraction ◽  
Acute Inflammation ◽  
Right Lobe ◽  
The Right ◽  
Acute Thyroiditis

Five days after tooth extraction, a 24-year-old woman developed acute inflammation of the right lobe of the thyroid gland, which after a while spontaneously healed.

BILATERAL PROPTOSIS - INITIAL AND RARE PRESENTATION: AML

2021 ◽  
pp. 17-18
Author(s):  
Tejasvini Chandra ◽  
Perwez Khan ◽  
Lubna Khan ◽  
Anshika Gupta
Keyword(s):  
Myeloid Leukemia ◽  
Blood Count ◽  
Complete Blood Count ◽  
Rare Condition ◽  
Metastatic Tumour ◽  
Blood Picture ◽  
Rare Presentation ◽  
Radiological Investigation ◽  
Presumptive Diagnosis ◽  
History Of

We report bilateral proptosis as the initial presentation of Acute Myeloid Leukemia (AML) in a child. An Eight year child presented with a history of painless proptosis in the both eyes within 10 days. Radiological investigation (CT scan) showed inltration of orbit with the metastatic tumour cell. AML was diagnosed with complete blood count, General Blood Picture (GBP) and bone marrow biopsy. The presumptive diagnosis of leukemic inltration of the orbit is made. We report this case as AML can rarely present in child as a bilateral proptosis due to leukemic inltration. Urgent treatment modality for this rare condition is radiation.

scholarly journals Thyroid Metastasis of Renal Cell Carcinoma

2011 ◽  
Vol 3 (2) ◽  
pp. 93-95 ◽  
Author(s):  
Bulent Citgez ◽  
Mehmet Uludag ◽  
Gurkan Yetkin ◽  
Esin Kabul Gurbulak ◽  
Banu Yılmaz Ozguven ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Previous History ◽  
Metastatic Tumor ◽  
Thyroid Metastasis ◽  
Thyroid Mass ◽  
History Of ◽  
Recurrent Malignancy

ABSTRACT Metastases to the thyroid gland are rare. We report the case of a 50-year-old man with an isolated thyroid metastasis from renal cell carcinoma (RCC), 3 years after radical nephrectomy for the primary disease. Although uncommon, if a patient with a previous history of malignancy has a new thyroid mass, it should be considered metastatic tumor of recurrent malignancy until proved otherwise.

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