A Comparison Between Two Imaging Techniques for the Diagnosis of Subacute Thyroiditis (De Quervain Thyroiditis)

Patricio González Espinoza; Claudio Liberman Guendelman; Lidya Nieves Quevedo Limón; Rodrigo Jaimovich Fernández

doi:10.1097/rlu.0b013e3181f49adc

SUB-ACUTE THYROIDITIS: ESR AS DIAGNOSTIC MARKER AND OPTIMUM DURATION OF PREDNISOLONE THERAPY

Journal of Saidu Medical College, Swat ◽

10.52206/jsmc.2015.5.1.582-585 ◽

1969 ◽

Vol 5 (1) ◽

pp. 582-585

Author(s):

ASADULLAH ◽

MAHID IQBAL ◽

IZAZ UR RAHMAN ◽

S.M.NAEEM ◽

IQBAL AHMAD

Keyword(s):

Thyroid Gland ◽

Steroid Therapy ◽

Subacute Thyroiditis ◽

Blood Picture ◽

High Grade Fever ◽

Prednisolone Therapy ◽

History Of ◽

De Quervain ◽

De Quervain Thyroiditis ◽

Acute Thyroiditis

BACKGROUND: Thyroiditis is an inflammation of the thyroid gland that can arise due to a variety ofcauses. Subacute thyroiditis or de Quervain thyroiditis is comparatively uncommon with recurrence rateof 5% patients over a 20-year period. It usually presents in the form of epidemics and mostly hasoverlapping symptoms, which leads to misdiagnosis.OBJECTIVE: To study sub-acute thyroiditis with the risks and benefits of treatment and consequencesof non treatment.PATIENTS AND METHODS: The study was conducted on seventy (70) patients who visited forconsultancy during April 2014 to May 2015. Their mean age was 37 years, having 28 male 42 females.Those who presented with symptoms of pain in front of neck, unilateral or bilateral, periodic generalizedbody aches, without having history of high grade fever, were included in the study after taking theirconsent. ESR, TFTs and complete blood picture of those having mildly enlarged or not palpable,painful and tender thyroid were done and recorded. They were divided into various groups for steroidtherapy. The patients were selected randomly.RESULTS: All the seventy patients having symptoms, suggestive of thyrioditis had markedly raisedESR with normal TFTs range and rest of the blood picture, were put on 40-45mg/day with tapering dosefor two to six weeks. Those who were put on six weeks steroid therapy had no recurrence, where asthose with duration less than six weeks time suffered from recurrence of symptoms.CONCLUSION: Subacute thyroditis presented with generalized bodyach and tender thyroid gland withraised ESR, when treated with 40-45mg/day prednisolone therapy for six weeks responded significantly.KEY WORDS: Thyroiditis, Subacute thyroiditis, Erythrocyte sedimentation rate, Steroid therapy.

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Subacute Thyroiditis in COVID-19 Patients

European Thyroid Journal ◽

10.1159/000511707 ◽

2020 ◽

pp. 1-3

Author(s):

Saeed Sohrabpour ◽

Farrokh Heidari ◽

Ebrahim Karimi ◽

Reza Ansari ◽

Ardavan Tajdini ◽

...

Keyword(s):

Respiratory Illness ◽

Subacute Thyroiditis ◽

Imaging Data ◽

Endocrine Glands ◽

C Reactive Protein ◽

Reactive Protein ◽

History Of ◽

De Quervain ◽

Novel Coronavirus ◽

De Quervain Thyroiditis

Introduction: Since December 2019, novel coronavirus (COVID-19) infection has been identified as the cause of an outbreak of respiratory illness in Wuhan, China. The classic presentation of COVID-19 infection was described as fever, myalgia, cough, and fatigue. Whether coronavirus can directly attack the endocrine glands is unclear. Objective: Post-viral subacute thyroiditis (SAT, de Quervain thyroiditis) has been reported following other viral infection. A limited number of SAT after COVID-19 infection have been reported up to now. Methods: Here, we reported 6 patients with SAT and positive COVID-19 serology tests. Demographic, clinical, biochemical, and imaging data were presented. Results: In this study, 6 patients (4 women and 2 men) with clinician manifestations and physical examination in favor of SAT were described. Cervical ultrasonography showed bilateral hypoechoic areas in the thyroid gland which was suggestive of SAT. Elevated C-reactive protein, erythrocyte sedimentation rate, free thyroxine, free tri-iodothyronine, and undetectable thyrotropin were found in laboratory evaluations. Both IgM and IgG were positive for COVID-19 infection, but the PCR tests were negative in all patients. Patients had history of working in a COVID center and/or family member hospitalized due to COVID-19 pneumonia. Patients were followed up for 1 month and were treated effectively with steroids. Conclusion: This report may help physicians to identify lesser-known manifestations and complications of COVID-19. Early diagnosis of COVID-19 infection results in the prevention of further transmission.

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Subacute thyroiditis after inactive SARS-CoV-2 vaccine

BMJ Case Reports ◽

10.1136/bcr-2021-244711 ◽

2021 ◽

Vol 14 (10) ◽

pp. e244711

Author(s):

Emre Sedar Saygılı ◽

Ersen Karakilic

Keyword(s):

Case Report ◽

Virus Vaccine ◽

Rare Case ◽

Viral Infections ◽

Subacute Thyroiditis ◽

De Quervain ◽

De Quervain Thyroiditis

Viral infections have often been associated with subacute (De Quervain) thyroiditis. Rare cases of subacute thyroiditis have been reported after vaccines. Various vaccines have been developed with different techniques against SARS-CoV-2. This case report presents a rare case of subacute thyroiditis after the inactive SARS-CoV-2 virus vaccine, CoronaVac.

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Thyroiditis de Quervain

Nuklearmedizin ◽

10.3413/nukmed-0536-12-10 ◽

2013 ◽

Vol 52 (04) ◽

pp. 137-140 ◽

Cited By ~ 4

Author(s):

R. Klett ◽

S. Braun ◽

M. Zimny ◽

S. Schenke

Keyword(s):

Predictive Factors ◽

Hormone Replacement ◽

Thyroid Volume ◽

Subacute Thyroiditis ◽

Overt Hypothyroidism ◽

Morphological Parameters ◽

De Quervain ◽

Overt Hyperthyroidism

SummaryBackground: Subacute thyroiditis is a usually self-limiting disease of the thyroid. However, approximately 0.5–15% of the patients require permanent thyroxine substitution. Aim was to determine predictive factors for the necessity of long-term hormone-replacement (LTH). Patients, methods: We retrospectively reviewed the records of 72 patients with subacute thyroiditis. Morphological and serological parameters as well as type of therapy were tested as predictive factors of consecutive hypothyroidism. Results: Mean age was 49 ± 11 years, f/m-ratio was 4.5 : 1. Thyroid pain and signs of hyperthyroidism were leading symptoms. Initial subclinical or overt hyperthyroidism was found in 20% and 37%, respectively. Within six months after onset 15% and 1.3% of the patients developed subclinical or overt hypothyroidism, respectively. At latest follow-up 26% were classified as liable to LTH. At onset the thyroid was enlarged in 64%, and at latest follow-up in 8.3%, with a significant reduction of the thyroid volume after three months. At the endpoint the thyroid volume was less in patients in the LTH group compared with the non-LTH group (41.7% vs. 57.2% of sex-adjusted upper norm, p = 0.041). Characteristic ultrasonographic features occurred in 74% of the patients in both lobes. Serological and morphological parameters as well as type of therapy were not related with the need of LTH. Conclusions: In this study the proportion of patients who received LTH was 26%. At the endpoint these patients had a lower thyroid volume compared with euthyroid patients. No predictive factors for LTH were found.

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Sonoelastography in de Quervain Thyroiditis

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2010-1595 ◽

2011 ◽

Vol 96 (2) ◽

pp. 289-290 ◽

Cited By ~ 16

Author(s):

Marek Ruchala ◽

Ewelina Szczepanek ◽

Jerzy Sowinski

Keyword(s):

De Quervain ◽

De Quervain Thyroiditis

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Serum myoglobin in thyroid disease

Acta Endocrinologica ◽

10.1530/acta.0.0940184 ◽

1980 ◽

Vol 94 (2) ◽

pp. 184-187 ◽

Cited By ~ 2

Author(s):

F. A. Karlsson ◽

P. A. Dahlberg ◽

P. Venge ◽

L. E. Roxin

Keyword(s):

Thyroid Disease ◽

Healthy Subjects ◽

Reference Range ◽

Subacute Thyroiditis ◽

Graves Disease ◽

Thyroid Disorders ◽

Muscular Weakness ◽

De Quervain ◽

Serum Myoglobin

Abstract. Serum myoglobin levels were measured longitudinally in patients undergoing therapy because of various thyroid disorders. Elevated myoglobin values - 72.6 (58.7–89.7) μg/l (mean ± sem) were found in a group of hypothyroid subjects. The degree of myoglobin increase seemed related to the severity of hypothyroidism. When rendered euthyroid the myoglobin levels of these patients were normalized − 41.0 (37.3–45.1) μg/l. In patients with hyperthyroidism, due to Graves' disease or subacute thyroiditis (de Quervain), only minor changes of myoglobin values within the reference range of healthy subjects, were measured. This suggests that mechanisms not affecting myoglobin release are responsible for the muscular weakness of thyrotoxic patients.

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