scholarly journals A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method

Engineering ◽  
2021 ◽  
Author(s):  
Chunxia Qiao ◽  
Ming Lv ◽  
Xinying Li ◽  
Xiaoling Lang ◽  
Shouqin Lv ◽  
...  
Keyword(s):  
Design Method ◽  
Human Antibody ◽  
Computer Aided ◽  
Antibody Design

scholarly journals Design Method of Circular Weft-Knitted Jacquard Fabric Based on Jacquard Module

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Peixiao Zheng ◽  
Gaoming Jiang ◽  
Honglian Cong
Keyword(s):  
Mathematical Modeling ◽  
Computer Aided Design ◽  
Theoretical Basis ◽  
Design Method ◽  
Two Dimensional ◽  
Design Procedures ◽  
Rapid Design ◽  
Computer Aided ◽  
Aided Design

Abstract Recently, there is an increasing interest in design of circular weft jacquard because of the pursuit of fashion and comfort. Aiming at the complexity of the computer-aided design method of the existing circular weft-knitted jacquard fabrics, which is not conducive to the rapid design and intelligible for designers, a design method was proposed to transform pattern notation into knitting diagram efficiently, which was based on knitting rules and its creation as a set of jacquard modules. Knitting characteristics of jacquard fabrics were studied as a precondition. On this basis, the design procedures of jacquard modules were analyzed and illustrated by taking tricolor bird's eye backing jacquard as an example. Jacquard modules with various jacquard effects were designed and stored in a jacquard module database. To mathematically describe pattern notation, knitting diagram, and jacquard module, two-dimensional matrixes were established by the method of mathematical modeling, and a corresponding algorithm for the transformation of the pattern to knitting information according to the knitting rules of jacquard modules, which can be applied to ordinary jacquard fabrics was summarized. The project of tricolor circular weft-knitted jacquard with bird's eye in the reverse and four-color air-layer jacquard were taken for instance to verify the models and algorithm. The results obtained show that the approach can efficiently and conveniently realize the designation and machine-knitting of weft-knitted jacquard fabric, which provide a theoretical basis and notation of modeling for the computer-aided design of circular weft-knitted jacquard fabrics.

scholarly journals Computational wrapping: A universal method to wrap 3D-curved surfaces with nonstretchable materials for conformal devices

2020 ◽  
Vol 6 (15) ◽  
pp. eaax6212 ◽  
Author(s):  
Yu-Ki Lee ◽  
Zhonghua Xi ◽  
Young-Joo Lee ◽  
Yun-Hyeong Kim ◽  
Yue Hao ◽  
...  
Keyword(s):  
Computer Aided Design ◽  
Reliable Method ◽  
Design Method ◽  
Universal Method ◽  
Curved Surfaces ◽  
Two Dimensional ◽  
Steel Sheets ◽  
Computer Aided ◽  
Conformal Structures ◽  
Aided Design

This study starts from the counterintuitive question of how we can render conventional stiff, nonstretchable, and even brittle materials sufficiently conformable to fully wrap curved surfaces, such as spheres, without failure. Here, we extend the geometrical design method of computational origami to wrapping. Our computational wrapping approach provides a robust and reliable method for fabricating conformal devices for arbitrary curved surfaces with a computationally designed nonpolyhedral developable net. This computer-aided design transforms two-dimensional (2D)–based materials, such as Si wafers and steel sheets, into various targeted conformal structures that can fully wrap desired 3D structures without fracture or severe plastic deformation. We further demonstrate that our computational wrapping approach enables a design platform that can transform conventional nonstretchable 2D-based devices, such as electroluminescent lighting and flexible batteries, into conformal 3D curved devices.

Comprehensive Satisfactory Design Method for Product Designs

2001 ◽  
Author(s):  
Eiji Adachi
Keyword(s):  
Decision Making ◽  
Design Method ◽  
Simultaneous Equations ◽  
Objective Functions ◽  
Identification Methods ◽  
Multi Objective ◽  
Sensitivity Coefficients ◽  
Design Variables ◽  
Computer Aided ◽  
Market Needs

Abstract Actual product designs aim to fulfill all product requirements of market needs and wants, which are technical or non-technical, logical or illogical, objective or subjective, and quantitative or qualitative. The actual product designs are objective-aiming designs and can be supposed to be multi-objective satisfactory designs with heterogeneous objective functions and dimensional design variables. To realize computer-aided product designs which can obtain rational and satisfactory solutions, we classify the objective functions and contrive methods to deal with non-theoretical, non-technical, subjective, or illogical objective functions as well. This paper shows all of our methods, including an expression of heterogeneous objective functions which consists of objective and evaluated values, a satisfactory design method by simultaneous equations which searches solutions sequentially, identification methods of non-theoretical or non-technical objective functions and sensitivity coefficients for the simultaneous equations, a decision-making method of promising solutions to fulfill product requirements, and also numerical applications of these methods to actual product designs.

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