Based on the 3DMine three-dimensional mining software, a geological database model of the Changpai area is established, and a three-dimensional model of the ore body is established based on the principle and geological understanding of the circle. We carried out sample combination by a geological database model to process ore bodies of erratic high grades. We also stablished a block model, and used single assignment and ordinary Kriging method to assign value to the block model, used attribute visualization to intuitively reflect the distribution law of the ore grade in a three-dimensional space, and the block report can quickly estimate the grade, volume, ore quantity, etc., of which the results are more accurate. The common Kriging method has obvious advantages in valuation, and it is worthy for further promotion in the estimation of uranium reserves.