scholarly journals Spontaneous bleeding from an unusual renal mass: A case of gestational choriocarcinoma related to previous pregnancy over a decade earlier

2021 ◽  
pp. 101614
Author(s):  
Yilu He ◽  
Varun Bhoopathy ◽  
David Habashy ◽  
Stuart Adams ◽  
Steve P. McCombie ◽  
...  
Keyword(s):  
Renal Mass ◽  
Spontaneous Bleeding ◽  
Previous Pregnancy ◽  
Gestational Choriocarcinoma

Ultrastructure of Choriocarcinoma in Vitro

1969 ◽  
Vol 27 ◽  
pp. 362-363
Author(s):  
John C. Garancis ◽  
R. A. Pattillo
Keyword(s):  
Cell Line ◽  
Physiological Function ◽  
Cell System ◽  
Bewo Cell ◽  
Bewo Cells ◽  
Gestational Choriocarcinoma ◽  
Bewo Cell Line

Growth of cell system (BeWo-cell line) derived from human gestational choriocarcinoma has been established and continuously maintained in-vitro. Furthermore, it is evident from the previous studies that this cell line has retained the physiological function of the placental trophoblasts, namely the synthesis of human chorionic gonadotrophil(HCG).The BeWo cells were relatively small and possessed single nuclei, thus indicating that this cell line consists exclusively of cytotrophoblasts. In some instances cells appeared widely separated and their lateral surfaces were provided with numerous microvilli (Fig.1).

Comparison of Choriocarcinoma and Normal Placenta

1971 ◽  
Vol 29 ◽  
pp. 324-325
Author(s):  
John C. Garancis ◽  
Roland A. Pattillo ◽  
Robert O. Hussa ◽  
Jon V. Straumfjord
Keyword(s):  
Cell Lines ◽  
Small Cells ◽  
Tissue Cultures ◽  
Glycogen Depletion ◽  
Cell Surfaces ◽  
Intercellular Spaces ◽  
Concomitant Increase ◽  
Gestational Choriocarcinoma ◽  
Cytoplasmic Glycogen ◽  
Normal Placenta

Two different cell lines (Be-Wo and Jar) of human gestational choriocarcinoma have been maintained in continuous tissue culture for a period of four and two years respectively without losing the ability to elaborate human chorionic gonadotropin (HCG). Tissue cultures, as revealed by electron microscopy, consisted of small cells with single nuclei. In some instances cell surfaces were provided with microvilli but more often the intercellular spaces were narrow and bridged by desmosomes. However, syncytium was not formed. Endoplasmic reticulum (ER) was poorly developed in both cell lines, except in some Be-Wo cells it was prominent. Golgi complex, lysosomes and numerous free ribosomes, as well as excessive cytoplasmic glycogen, were present in all cells (Fig. 1). Glycogen depletion and concomitant increase of ER were observed in many cells following a single dose of 10 ugm/ml of adrenalin added to medium (Fig. 2).

981: Mass Size Predicts Probability of Renal Mass Malignancy

2005 ◽  
Vol 173 (4S) ◽  
pp. 265-266 ◽  
Author(s):  
James R. Johannes ◽  
Deborah Glassman ◽  
George Kallingal ◽  
Dolores Byrne ◽  
Stephen E. Strup ◽  
...  
Keyword(s):  
Renal Mass ◽  
Mass Size

1290: Laparoscopic Partial Nephrectomy (LPN) for Renal Mass: Washington University Experience with 99 Cases

2004 ◽  
Vol 171 (4S) ◽  
pp. 340-340 ◽  
Author(s):  
Caroline D. Ames ◽  
David Lieber ◽  
Ramakrishna Venkatesh ◽  
Richard Vanlangendock ◽  
Chandru P. Sundaram ◽  
...  
Keyword(s):  
Partial Nephrectomy ◽  
Renal Mass ◽  
Laparoscopic Partial Nephrectomy ◽  
University Experience ◽  
Washington University

Low Prevalence of the Factor V Leiden Mutation Among “Severe” Hemophiliacs with a “Milder” Bleeding Diathesis

1995 ◽  
Vol 74 (05) ◽  
pp. 1255-1258 ◽  
Author(s):  
Arnaldo A Arbini ◽  
Pier Mannuccio Mannucci ◽  
Kenneth A Bauer
Keyword(s):  
Hemophilia A ◽  
Factor V Leiden ◽  
Protein S ◽  
Factor Ix ◽  
Hemophilia B ◽  
Factor V ◽  
Bleeding Diathesis ◽  
Mutation Site ◽  
Spontaneous Bleeding ◽  
Factor V Leiden Mutation

SummaryPatients with hemophilia A and B and factor levels less than 1 percent of normal bleed frequently with an average number of spontaneous bleeding episodes of 20–30 or more. However there are patients with equally low levels of factor VIII or factor IX who bleed once or twice per year or not at all. To examine whether the presence of a hereditary defect predisposing to hypercoagulability might play a role in amelio rating the hemorrhagic tendency in these so-called “mild severe” hemophiliacs, we determined the prevalence of prothrombotic defects in 17 patients with hemophilia A and four patients with hemophilia B selected from 295 and 76 individuals with these disorders, respectively, followed at a large Italian hemophilia center. We tested for the presence of the Factor V Leiden mutation by PCR-amplifying a fragment of the factor V gene which contains the mutation site and then digesting the product with the restriction enzyme Mnll. None of the patients with hemophilia A and only one patient with hemophilia B was heterozygous for Factor V Leiden. None of the 21 patients had hereditary deficiencies of antithrombin III, protein C, or protein S. Our results indicate that the milder bleeding diathesis that is occasionally seen among Italian hemophiliacs with factor levels that are less than 1 percent cannot be explained by the concomitant expression of a known prothrombotic defect.

Acquired Factor XI Inhibitors in Two Patients with Hereditary Factor XI Deficiency

1984 ◽  
Vol 51 (03) ◽  
pp. 371-375 ◽  
Author(s):  
Kangathevy Morgan ◽  
Sandra Schiffman ◽  
Donald Feinstein
Keyword(s):  
Protein A ◽  
Lambda Light Chain ◽  
Factor Xi ◽  
Spontaneous Bleeding ◽  
Factor Xi Deficiency ◽  
Hereditary Factor ◽  
Coagulation Mechanism ◽  
Factor Xia ◽  
Polyclonal Igg ◽  
Glass Surfaces

SummaryTwo patients with hereditary factor XI deficiency developed inhibitors following plasma transfusions. Neither had severe spontaneous bleeding. The patients’ plasmas neutralized both factor XI in plasma, purified factor XI, and purified factor XIa. The inhibitor in both patients’ plasmas adsorbed to Protein A- Sepharose. The inhibitors eluted from Protein A-Sepharose were partially neutralized by kappa and lambda light chain antisera indicating that they were polyclonal IgG antibodies. Both inhibitors markedly decreased adsorption of factor XI to glass surfaces. The cleavage of factor XI by trypsin was unaffected by the inhibitors. The lack of severe spontaneous bleeding in both of these patients strongly suggests that an alternate coagulation mechanism bypassing factor XI must compensate for this severe defect.

P 736. Benign Enlargement of Subarachnideal Spaces and Subdural Hematoma in an Infant: Spontaneous Bleeding, Child Abuse, or Bleeding Disorder?

2018 ◽  
Author(s):  
Kristine Adam ◽  
Leo Rossler ◽  
Christine Decker ◽  
Charlotte Thiels ◽  
Christoph Heyer ◽  
...  
Keyword(s):  
Child Abuse ◽  
Subdural Hematoma ◽  
Bleeding Disorder ◽  
Spontaneous Bleeding

Changing Practice In The Management Of Small Renal Mass

2020 ◽  
Vol 16 (1) ◽  
pp. 1-4
Author(s):  
Md Jahangir Kabir
Keyword(s):  
Renal Mass ◽  
Small Renal Mass ◽  
Changing Practice

Abstract Not Available Bangladesh Journal of Urology, Vol. 16, No. 1, Jan 2013 p.1-4

An Atypical Case of Renal Mass - A Case Study

2020 ◽  
Vol 15 (2) ◽  
pp. 56-58
Author(s):  
Shafiqur Rahman ◽  
B Ahmed ◽  
ATM Mowladad Chowdhury ◽  
Mirza M Hasan ◽  
Sayedul Islam
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Clinical Diagnosis ◽  
Renal Cell ◽  
Renal Mass ◽  
Clinical Presentation ◽  
Atypical Case ◽  
Renal Tuberculosis

A forty eight year old woman with the clinical diagnosis of renal mass due to renal cell carcinoma was found to have renal tuberculosis. The clinical presentation and management are being discussed. Bangladesh Journal of Urology, Vol. 15, No. 2, July 2012 p.56-58

A malignant looking renal mass is not always renal cancer

2017 ◽  
Author(s):  
Oluwaseun Anyiam ◽  
Rabia Chaudhry ◽  
Damian Hanbury ◽  
Felicity Kaplan
Keyword(s):  
Renal Cancer ◽  
Renal Mass
Sign in / Sign up

Export Citation Format

Share Document