Linear and non-linear analyses of autonomic modulation in uncontrolled and controlled elderly resistant hypertensives

Poor glycemic control impacts linear and non-linear dynamics of heart rate in DM type 2

Revista Brasileira de Medicina do Esporte ◽

10.1590/1517-869220152104150003 ◽

2015 ◽

Vol 21 (4) ◽

pp. 313-317 ◽

Cited By ~ 5

Author(s):

Daniela Bassi ◽

Vivian Maria Arakelian ◽

Renata Gonçalves Mendes ◽

Flávia Cristina Rossi Caruso ◽

José Carlos Bonjorno Júnior ◽

...

Keyword(s):

Heart Rate ◽

Glycemic Control ◽

Autonomic Neuropathy ◽

Fasting Glucose ◽

Poor Glycemic Control ◽

Cardiovascular Autonomic Neuropathy ◽

Autonomic Modulation ◽

Cardiac Autonomic Modulation ◽

Non Linear

INTRODUCTION: It is well known that type 2 diabetes mellitus (T2DM) produces cardiovascular autonomic neuropathy (CAN), which may affect the cardiac autonomic modulation. However, it is unclear whether the lack of glycemic control in T2DM without CAN could impact negatively on cardiac autonomic modulation. Objective: To evaluate the relationship between glycemic control and cardiac autonomic modulation in individuals with T2DM without CAN. Descriptive, prospective and cross sectional study.METHODS: Forty-nine patients with T2DM (51±7 years) were divided into two groups according to glycosylated hemoglobin (HbA1c): G1≤7% and G2>7.0%. Resting heart rate (HR) and RR interval (RRi) were obtained and calculated by linear (Mean iRR; Mean HR; rMSSD; STD RR; LF; HF; LF/HF, TINN and RR Tri,) and non-linear (SD1; SD2; DFα1; DFα2, Shannon entropy; ApEn; SampEn and CD) methods of heart rate variability (HRV). Insulin, HOMA-IR, fasting glucose and HbA1c were obtained by blood tests.RESULTS: G2 (HbA1c≤7%) showed lower values for the mean of iRR; STD RR; RR Tri, TINN, SD2, CD and higher mean HR when compared with G1 (HbA1c > 7%). Additionally, HbA1c correlated negatively with mean RRi (r=0.28, p=0.044); STD RR (r=0.33, p=0.017); RR Tri (r=-0.35, p=0.013), SD2 (r=-0.39, p=0.004) and positively with mean HR (r=0.28, p=0.045). Finally, fasting glucose correlated negatively with STD RR (r=-0.36, p=0.010); RR Tri (r=-0.36, p=0.010); TINN (r=-0.33, p=0.019) and SD2 (r=-0.42, p=0.002).CONCLUSION: We concluded that poor glycemic control is related to cardiac autonomic modulation indices in individuals with T2DM even if they do not present cardiovascular autonomic neuropathy.

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Erratum to: Cardiac autonomic modulation in judo athletes: evaluation by linear and non-linear method

Sport Sciences for Health ◽

10.1007/s11332-016-0262-4 ◽

2016 ◽

Vol 12 (1) ◽

pp. 131-131

Author(s):

Patrícia Sousa Araújo ◽

Wellington Roberto Gomes de Carvalho ◽

Francisco Navarro ◽

Bruno Rodrigues ◽

Bruno Bavaresco Gambassi ◽

...

Keyword(s):

Linear Method ◽

Autonomic Modulation ◽

Cardiac Autonomic Modulation ◽

Non Linear ◽

Judo Athletes

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Cardiac autonomic modulation in judo athletes: evaluation by linear and non-linear method

Sport Sciences for Health ◽

10.1007/s11332-015-0256-7 ◽

2016 ◽

Vol 12 (1) ◽

pp. 125-130 ◽

Cited By ~ 3

Author(s):

Patrícia Souza Araújo ◽

Wellington Roberto Gomes de Carvalho ◽

Francisco Navarro ◽

Bruno Rodrigues ◽

Bruno Bavaresco Gambassi ◽

...

Keyword(s):

Linear Method ◽

Autonomic Modulation ◽

Cardiac Autonomic Modulation ◽

Non Linear ◽

Judo Athletes

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Cardiac autonomic modulation in juvenile idiopathic arthritis with use of biological medication: case report

Journal of Human Growth and Development ◽

10.7322/jhgd.v30.9962 ◽

2020 ◽

Vol 30 (1) ◽

pp. 129-134

Author(s):

Patrícia Merly Martinelli ◽

Ana Carolina Gonçalves de Abreu ◽

José Rener Cordeiro da Silva ◽

Asami Takahara Vasconscelos ◽

Adilson Monteiro ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Juvenile Idiopathic Arthritis ◽

Case Report ◽

Joint Damage ◽

Response To Therapy ◽

Functional Evaluation ◽

Autonomic Modulation ◽

Cardiac Autonomic Modulation ◽

Non Linear

Introduction: The introduction of biological medication in Juvenile Idiopathic Arthritis (JIA) proposes better therapeutic results with decreased pain and inflammation and consequent reduction in joint damage. The autonomic state can be a predictor for verifying the response to immunomodulation therapy. Thus, measuring heart rate variability can express autonomous behavior and possibly accompany the response to therapy through the expression of the inflammatory condition. Objective: Analysis of heart rate variability in a child with Juvenile Idiopathic Arthritis using the anti-Tumor Necrosis Factor. Methods: This is a clinical case report of an 8-year-old male with a diagnosis of JIA - oligoarticular form, using etanercept, admitted to Clínica Escola de Fisioterapia UNINORTE, Acre, Brazil in 2017. We analyzed laboratory and imaging tests, kinetic-functional evaluation, examination of cardiac autonomic modulation and physiotherapeutic treatment for analgesic, anti-inflammatory purposes, gaining flexibility, strength and postural re-education, according to CARE guidelines, case report guidelines. Results: After medication administration, there was a decrease in pain and normalization of serum creatinine (0.50 mg / dL) and CRP (less than 6 mg / dL) and an increase in erythrocyte sedimentation rate (17 mm3). In the examination of heart rate variability, the linear indices in the time domain showed a predominance of parasympathetic activity (RMSSD: 35ms), with decreased sympathetic control measured through the frequency domain (LF: 27.1 un). However, non-linear methods showed low variability with little dispersion of RR intervals. Conclusion: In the present report, the linear indices showed parasympathetic predominance and in the non-linear analysis a low heart rate variability with abnormal and insufficient adaptation of the autonomic nervous system in a child with juvenile idiopathic arthritis using biological medication.

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B. The Non-Linear Calculations for Pulsating Stars

Symposium - International Astronomical Union ◽

10.1017/s0074180900019008 ◽

1967 ◽

Vol 28 ◽

pp. 105-176

Author(s):

Robert F. Christy

Keyword(s):

Major Part ◽

Afternoon Session ◽

Discussion Session ◽

Pulsating Stars ◽

Fourth Symposium ◽

Non Linear ◽

Considerable Discussion ◽

Informal Approach ◽

Preceding Session

(Ed. note: The custom in these Symposia has been to have a summary-introductory presentation which lasts about 1 to 1.5 hours, during which discussion from the floor is minor and usually directed at technical clarification. The remainder of the session is then devoted to discussion of the whole subject, oriented around the summary-introduction. The preceding session, I-A, at Nice, followed this pattern. Christy suggested that we might experiment in his presentation with a much more informal approach, allowing considerable discussion of the points raised in the summary-introduction during its presentation, with perhaps the entire morning spent in this way, reserving the afternoon session for discussion only. At Varenna, in the Fourth Symposium, several of the summaryintroductory papers presented from the astronomical viewpoint had been so full of concepts unfamiliar to a number of the aerodynamicists-physicists present, that a major part of the following discussion session had been devoted to simply clarifying concepts and then repeating a considerable amount of what had been summarized. So, always looking for alternatives which help to increase the understanding between the different disciplines by introducing clarification of concept as expeditiously as possible, we tried Christy's suggestion. Thus you will find the pattern of the following different from that in session I-A. I am much indebted to Christy for extensive collaboration in editing the resulting combined presentation and discussion. As always, however, I have taken upon myself the responsibility for the final editing, and so all shortcomings are on my head.)

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