Working memory training impacts neural activity during untrained cognitive tasks in people with multiple sclerosis

2021 ◽  
Vol 335 ◽  
pp. 113487
Author(s):  
Zachary P. Turtola ◽  
Thomas J. Covey
2018 ◽  
Vol 14 (1) ◽  
pp. 142-154 ◽  
Author(s):  
Laura Bonzano ◽  
Ludovico Pedullà ◽  
Matteo Pardini ◽  
Andrea Tacchino ◽  
Paola Zaratin ◽  
...  

2013 ◽  
Vol 21 (2) ◽  
pp. 146-173 ◽  
Author(s):  
Stephan Heinzel ◽  
Stefanie Schulte ◽  
Johanna Onken ◽  
Quynh-Lam Duong ◽  
Thomas G. Riemer ◽  
...  

2009 ◽  
Vol 27 (3) ◽  
pp. 225-235 ◽  
Author(s):  
Annamarie Vogt ◽  
Ludwig Kappos ◽  
Pasquale Calabrese ◽  
Markus Stöcklin ◽  
Leo Gschwind ◽  
...  

2018 ◽  
Vol 4 (1) ◽  
pp. 205521731774762 ◽  
Author(s):  
Thomas J Covey ◽  
Janet L Shucard ◽  
Ralph HB Benedict ◽  
Bianca Weinstock-Guttman ◽  
David W Shucard

Background Few studies of cognitive rehabilitation in multiple sclerosis (MS) have targeted working memory specifically. Objective We examined the effects of n-back working memory training on cognitive performance and brain function in patients with MS. Methods Patients with MS ( n = 12) and healthy controls (HC; n = 12) underwent 20 sessions of n-back working memory training. Before and after training (pre- and posttest) cognitive event-related potential (ERP) measures were obtained during a 3-back task. In addition, a battery of cognitive tests was administered. Results Following n-back training, both MS patients and HCs showed significant improvement on tests of working memory, processing speed, complex attention, and reasoning ability. MS and HCs also exhibited an enhancement of N2 ERP component amplitude, and earlier N2 and P3 latencies, following n-back training. Conclusions Targeted training of working memory with the n-back task may improve cognitive function in MS. Enhancement of N2 ERP component amplitude and shorter N2 and P3 latency following training in patients with MS is consistent with plasticity of neural processes that are involved in working memory.


2017 ◽  
Vol 29 (8) ◽  
pp. 1177-1192 ◽  
Author(s):  
Christine Till ◽  
Bravina Kuni ◽  
Elisea De Somma ◽  
E. Ann Yeh ◽  
Brenda Banwell

2014 ◽  
Author(s):  
Tiina Salminen ◽  
Simone Kuhn ◽  
Torsten Schubert

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