Protective role of puerarin on lead-induced alterations of the hepatic glutathione antioxidant system and hyperlipidemia in rats

2011 ◽  
Vol 49 (12) ◽  
pp. 3119-3127 ◽  
Author(s):  
Chan-Min Liu ◽  
Jie-Qiong Ma ◽  
Yun-Zhi Sun
Keyword(s):  
Antioxidant System ◽  
Protective Role ◽  
Glutathione Antioxidant System ◽  
Hepatic Glutathione

Control of Oxidative Reactions of Hemoglobin in the Design of Blood Substitutes: Role of the Ascorbate-Glutathione Antioxidant System

2009 ◽  
Vol 33 (2) ◽  
pp. 115-126 ◽  
Author(s):  
Jan Simoni ◽  
Javier Villanueva-Meyer ◽  
Grace Simoni ◽  
John F. Moeller ◽  
Donald E. Wesson
Keyword(s):  
Antioxidant System ◽  
Blood Substitutes ◽  
Glutathione Antioxidant System ◽  
Oxidative Reactions

In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity

2010 ◽  
Vol 85 (5) ◽  
pp. 525-535 ◽  
Author(s):  
Anna Vávrová ◽  
Olga Popelová ◽  
Martin Štěrba ◽  
Eduard Jirkovský ◽  
Pavlína Hašková ◽  
...  
Keyword(s):  
Antioxidant System ◽  
Glutathione Antioxidant System ◽  
In Vitro Assessment

The role of the glutathione antioxidant system in gut barrier failure in a rodent model of experimental necrotizing enterocolitis

Surgery ◽  
2004 ◽  
Vol 136 (3) ◽  
pp. 557-566 ◽  
Author(s):  
Natasha Kelly ◽  
Kerri Friend ◽  
Patricia Boyle ◽  
Xiao Ru Zhang ◽  
Catarina Wong ◽  
...  
Keyword(s):  
Necrotizing Enterocolitis ◽  
Antioxidant System ◽  
Rodent Model ◽  
Gut Barrier ◽  
Glutathione Antioxidant System ◽  
Barrier Failure ◽  
Gut Barrier Failure

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

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