Effect of vanillin and ethyl vanillin on cytochrome P450 activity in vitro and in vivo

2012 ◽  
Vol 50 (6) ◽  
pp. 1897-1901 ◽  
Author(s):  
Xiao-min Chen ◽  
Min Wei ◽  
Hai-mou Zhang ◽  
Cheng-hao Luo ◽  
Yi-kun Chen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Ethyl Vanillin ◽  
Cytochrome P450 Activity ◽  
P450 Activity

Interspecies differences in the cytochrome P450 activity of hepatocytes exposed to PLGA and silica nanoparticles: an in vitro and in vivo investigation

Nanoscale ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 5171-5181 ◽  
Author(s):  
Raphaël Cornu ◽  
Nathalie Rougier ◽  
Yann Pellequer ◽  
Alf Lamprecht ◽  
Paul Hamon ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Silica Nanoparticles ◽  
Interspecies Differences ◽  
Hepatic Cells ◽  
Cytochrome P450 Activity ◽  
Set Up ◽  
P450 Activity

This study emphasizes the interest to set up relevant in vitro models using human hepatic cells to evaluate the hepatotoxicity of nanomedicines.

In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores

2012 ◽  
Vol 41 (2) ◽  
pp. 390-397 ◽  
Author(s):  
Lies De Bock ◽  
Koen Boussery ◽  
Myriam Van Winckel ◽  
Peter De Paepe ◽  
Xavier Rogiers ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Liver Disease ◽  
End Stage Liver Disease ◽  
Cytochrome P450 Activity ◽  
End Stage ◽  
P450 Activity

Mediation of in Vitro Cytochrome P450 Activity by Common Pharmaceutical Excipients

2013 ◽  
Vol 10 (7) ◽  
pp. 2739-2748 ◽  
Author(s):  
Philip Martin ◽  
Marco Giardiello ◽  
Tom O. McDonald ◽  
Steven P. Rannard ◽  
Andrew Owen
Keyword(s):  
Cytochrome P450 ◽  
Pharmaceutical Excipients ◽  
Cytochrome P450 Activity ◽  
P450 Activity
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