Two generation reproduction toxicity study of GmDREB3 gene modified wheat in Wistar rats

2021 ◽  
pp. 112310
Author(s):  
Jie Tian ◽  
Xianghong Ke ◽  
Yuan Yuan ◽  
Wenxiang Yang ◽  
Xiaoqiao Tang ◽  
...  
2015 ◽  
Vol 56 ◽  
pp. 147-154 ◽  
Author(s):  
André Wolterbeek ◽  
Thies Oosterwijk ◽  
Steffen Schneider ◽  
Robert Landsiedel ◽  
Didima de Groot ◽  
...  

2015 ◽  
Vol 22 (3) ◽  
pp. 11 ◽  
Author(s):  
Pallavi Shrirang Jamadagni ◽  
Shrirang B. Jamadagni ◽  
Arjun Singh ◽  
Rajendra Kumar Singh ◽  
Sachchidanand N. Upadhyay ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Cheng-Chih Tsai ◽  
Sew-Fen Leu ◽  
Quan-Rong Huang ◽  
Lan-Chun Chou ◽  
Chun-Chih Huang

Three lactic acid bacterial strains,Lactobacillus plantarum, HK006, and HK109, andPediococcus pentosaceusPP31 exhibit probiotic potential as antiallergy agents, both in vitro and in vivo. However, the safety of these new strains requires evaluation when isolated from infant faeces or pickled cabbage. Multiple strains (HK006, HK109, and PP31) were subject to a bacterial reverse mutation assay and a short-term oral toxicity study. The powder product exhibited mutagenic potential inSalmonellaTyphimurium strains TA98 and TA1535 (with or without metabolic activation). In the short-term oral toxicity study, rats received a normal dosage of 390 mg/kg/d (approximately9×109 CFU/kg/d) or a high dosage of 1950 mg/kg/d (approximately4.5×1010 CFU/kg/d) for 28 d. No adverse effects were observed regarding the general condition, behaviour, growth, feed and water consumption, haematology, clinical chemistry indices, organ weights, or histopathologic analysis of the rats. These studies have demonstrated that the consumption of multiple bacterial strains is not associated with any signs of mutagenicity ofS.Typhimurium or toxicity in Wistar rats, even after consuming large quantities of bacteria.


2010 ◽  
pp. 125 ◽  
Author(s):  
Dirikolu ◽  
Thushara Chakkath ◽  
Susan Ball-Kell ◽  
Christy Elamma ◽  
Timothy M. Fan ◽  
...  

2012 ◽  
Vol 10 (2) ◽  
pp. 101-1
Author(s):  
Aree Thinkratok ◽  
Parin Suwannaprapha ◽  
Rungrudee Srisawat


2011 ◽  
Vol 32 (2) ◽  
pp. 173-174
Author(s):  
Steffen Schneider ◽  
Robert Landsiedel ◽  
Wendel Wohlleben ◽  
André Wolterbeek ◽  
Ine Waalkens-Berendsen ◽  
...  

2020 ◽  
Vol 7 ◽  
pp. 610-623 ◽  
Author(s):  
Lotte Geerlofs ◽  
Zhiyong He ◽  
Sa Xiao ◽  
Zhi-Cheng Xiao

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