90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats

2021 ◽  
pp. 112780
Author(s):  
Shu-Chieh Hu ◽  
Seonggi Min ◽  
Hyun-Ki Kang ◽  
Dong-Jin Yang ◽  
Mallikarjuna Basavarajappa ◽  
...  
Keyword(s):  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Twenty-Eight-Day Repeated Inhalation Toxicity Study of Aluminum Oxide Nanoparticles in Male Sprague-Dawley Rats

2018 ◽  
Vol 34 (4) ◽  
pp. 343-354 ◽  
Author(s):  
Yong-Soon Kim ◽  
Yong-Hyun Chung ◽  
Dong-Seok Seo ◽  
Hyun-Sung Choi ◽  
Cheol-Hong Lim
Keyword(s):  
Aluminum Oxide ◽  
Toxicity Study ◽  
Oxide Nanoparticles ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Aluminum Oxide Nanoparticles ◽  
Sprague Dawley Rats

Twenty-Eight-Day Inhalation Toxicity Study of Silver Nanoparticles in Sprague-Dawley Rats

2007 ◽  
Vol 19 (10) ◽  
pp. 857-871 ◽  
Author(s):  
Jun Ho Ji ◽  
Jae Hee Jung ◽  
Sang Soo Kim ◽  
Jin-Uk Yoon ◽  
Jung Duck Park ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

CROSS-FOSTERING INHALATION TOXICITY STUDY WITH HCFC-123 IN LACTATING SPRAGUE-DAWLEY RATS

2001 ◽  
Vol 13 (8) ◽  
pp. 671-687 ◽  
Author(s):  
Jochen Buschmann ◽  
Wilfried Bartsch ◽  
Clemens Dasenbrock ◽  
Rainer Fuhst ◽  
Gerhard Pohlmann ◽  
...  
Keyword(s):  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Cross Fostering ◽  
Hcfc 123

Twenty-eight-day repeated inhalation toxicity study of nano-sized lanthanum oxide in male sprague-dawley rats

2016 ◽  
Vol 32 (4) ◽  
pp. 1226-1240 ◽  
Author(s):  
Seo-Ho Shin ◽  
Cheol-Hong Lim ◽  
Yong-Soon Kim ◽  
Yong-Hoon Lee ◽  
Sung-Hwan Kim ◽  
...  
Keyword(s):  
Lanthanum Oxide ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Twenty-Eight-Day Repeated Inhalation Toxicity Study of Nano-Sized Neodymium Oxide in Male Sprague-Dawley Rats

2017 ◽  
Vol 33 (3) ◽  
pp. 239-253 ◽  
Author(s):  
Yong-Soon Kim ◽  
Cheol-Hong Lim ◽  
Seo-Ho Shin ◽  
Jong-Choon Kim
Keyword(s):  
Neodymium Oxide ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Acute and 28-Day Repeated Inhalation Toxicity Study of Glycolic Acid in Male Sprague-Dawley Rats

In Vivo ◽  
2019 ◽  
Vol 33 (5) ◽  
pp. 1507-1519 ◽  
Author(s):  
SEONG KWANG LIM ◽  
JEAN YOO ◽  
HAEWON KIM ◽  
WOONG KIM ◽  
ILSEOB SHIM ◽  
...  
Keyword(s):  
Glycolic Acid ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Subacute inhalation toxicity study of synthetic amorphous silica nanoparticles in Sprague-Dawley rats

2017 ◽  
Vol 29 (12-14) ◽  
pp. 567-576 ◽  
Author(s):  
Jae Hoon Shin ◽  
KiSoo Jeon ◽  
Jin Kwon Kim ◽  
Younghun Kim ◽  
Mi Seong Jo ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Synthetic Amorphous Silica

Safety Assessment of a Hydroethanolic Extract of Caralluma fimbriata

2013 ◽  
Vol 32 (5) ◽  
pp. 385-394 ◽  
Author(s):  
Antoinette Y. Odendaal ◽  
Narendra S. Deshmukh ◽  
Tennille K. Marx ◽  
Alexander G. Schauss ◽  
John R. Endres ◽  
...  
Keyword(s):  
Developmental Toxicity ◽  
Toxicity Study ◽  
Developmental Study ◽  
Sprague Dawley ◽  
Oral Toxicity ◽  
Toxicological Assessment ◽  
Sprague Dawley Rats ◽  
Chromosomal Aberration Test ◽  
Hydroethanolic Extract

This toxicological assessment evaluated the safety of a hydroethanolic extract prepared from Caralluma fimbriata (CFE), a dietary supplement marketed worldwide as an appetite suppressant. Studies included 2 in vitro genotoxicity assays, a repeated dose oral toxicity study, and a developmental study in rats. No evidence of in vitro mutagenicity or clastogenicity surfaced in the in vitro studies at concentrations up to 5000 μg of extract/plate (Ames test) or 5000 μg of extract/mL (chromosomal aberration test). No deaths or treatment-related toxicity were seen in the 6-month chronic oral toxicity study in Sprague-Dawley rats conducted at 3 doses (100, 300, and 1000 mg/kg body weight (bw)/d). The no observed effect level for CFE in this study was considered to be 1000 mg/kg bw/d. A prenatal developmental toxicity study conducted at 3 doses (250, 500, and 1000 mg/kg bw/d) in female Sprague-Dawley rats resulted in no treatment-related external, visceral, or skeletal fetal abnormalities, and no treatment-related maternal or pregnancy alterations were seen at and up to the maximum dose tested. CFE was not associated with any toxicity or adverse events.

scholarly journals Acute Toxicity Study of Standardized Mitragyna speciosa Korth Aqueous Extract in Sprague Dawley Rats

2012 ◽  
Vol 1 (2) ◽  
Author(s):  
Mohd Saleh Ahmad Kamal ◽  
Ahmad Rohi Ghazali ◽  
Noral ‘Ashikin Yahya ◽  
Mohd Isa Wasiman ◽  
Zakiah Ismail
Keyword(s):  
Acute Toxicity ◽  
Aqueous Extract ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Mitragyna Speciosa ◽  
Acute Toxicity Study ◽  
Sprague Dawley Rats
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