Effects of riboflavin and desferrioxamine B on Fe(II) oxidation by O2

Here we archive a protocol that can be used to determine competition between a siderophore (ferrioxamine B) and humic like binding sites that are present in marine DOM. We use the NICA-Donnan model to describe binding by humic like binding sites in DOM. Constants for Fe binding to marine DOM are taken from Zhu et al., (2021). Thermodynamic constants describing binding between major ions, iron and ferrioxamine B are taken from Schijf and Burns, (2016). References Schijf, J., Burns, S.M., 2016. Determination of the Side-Reaction Coefficient of Desferrioxamine B in Trace-Metal-Free Seawater. Front. Mar. Sci. 3, 117. https://doi.org/10.3389/fmars.2016.00117 Zhu, K., Birchill, A.J., Milne, A., Ussher, S.J., Humphreys, M.P., Carr, N., Mahaffey, C., Lohan, M.C., Achterberg, E.P., Gledhill, M., 2021a. Equilbrium calculations of iron speciation and apparent iron solubility in the Celtic Sea at ambient pH using the NICA-Donnan model. Mar. Chem

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Distribution of desferrioxamine-B-extractable soluble manganese(III) and particulate MnO2 in the St. Lawrence Estuary, Canada

Marine Chemistry ◽

10.1016/j.marchem.2018.11.005 ◽

2019 ◽

Vol 208 ◽

pp. 70-82 ◽

Cited By ~ 5

Author(s):

Matthew R. Jones ◽

Véronique E. Oldham ◽

George W. Luther ◽

Alfonso Mucci ◽

Bradley M. Tebo

Keyword(s):

Lawrence Estuary ◽

Desferrioxamine B ◽

St Lawrence Estuary

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Iron(III) complexation by desferrioxamine B in acidic aqueous solutions. The formation of binuclear complex diferrioxamine B

Inorganica Chimica Acta ◽

10.1016/s0020-1693(00)86494-4 ◽

1983 ◽

Vol 78 ◽

pp. 87-92 ◽

Cited By ~ 7

Author(s):

Mladen Biruš ◽

Zdravko Bradić ◽

Nikola Kujundẑić ◽

Marijan Pribanić

Keyword(s):

Aqueous Solutions ◽

Binuclear Complex ◽

Desferrioxamine B

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Prevention of UVI Precipitation in Alkaline Aqueous Solutions by the Siderophore Desferrioxamine B

10.26434/chemrxiv.13032428 ◽

2020 ◽

Author(s):

Matthew Kirby ◽

Jason Louis Sonnenberg ◽

Jonathan S. Watson ◽

Dominik Weiss

Keyword(s):

Functional Group ◽

Experimental Studies ◽

Binding Mode ◽

Batch Experiments ◽

Desferrioxamine B ◽

Waste Storage ◽

Contaminant Sources ◽

Waste Repositories ◽

Saline Solutions ◽

The Impact

In alkaline and saline solutions, uranium VI (UVI) forms uranyl salts, limiting its mobility in leachates released from nuclear waste repositories into groundwater. However, recent experimental and computational work suggested that natural organic molecules widely present in groundwater such as siderophores could potentially prevent solid precipitation because of the formation of stable UVI-siderophore complexes. It is important we assess the impact of siderophores on aqueous UVI chemistry as they could mobilise UVI from contaminated land and radioactive waste storage and disposal sites. Here we test this hypothesis by combining for the first time experimental studies on uranium precipitation in alkaline pH in the presence of desferrioxamine B (DFOB) and electron structure method calculation of uranyl – hydroxamate complexes to assess their stability. Stirred batch experiments containing 0 to 420 µM DFOB, 42 µM UVI and 0.1 M NaCl were conducted at pH 11.5. DFT was employed to explore the relative stability of different UVI-hydroxamate complexes, representative of the local binding mode of DFOB. During the stirred batch experiments, 5%, 11-12%, 41-53%, 95-96% and 100% of UVI passes through the filter membranes (0.2-1 µm pore diameter) after 24 hours when 0, 4.2, 42, 130 and 420 µM DFOB was added to solution. The DFT results suggest one hydroxamate functional group is most likely to complex with UVI with ∆rG calculated as +3 kJ/mol and -9 kJ/mol for [UO2(OH)3(Lmono)]2- and [UO2(OH)2(L)]- respectively. Conversion of the experimentally derived log β (-1.2 ± 0.3) through the equation ∆rG = -2.303RTlogβ provides ∆rG of +7 kJ/mol, similar to the ∆rG of these two complexes. The results of our study confirm that UVI precipitation could be hindered by the formation of a DFOB complex with UVI complexation through a single hydroxamate functional group as a likely mechanism. These results highlight the mobilising effect siderophores have on UVI from contaminant sources and need to be incorporated in environmental risk assessment studies.

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Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: comparison with desferrioxamine-B

Dalton Transactions ◽

10.1039/c4dt02978j ◽

2015 ◽

Vol 44 (11) ◽

pp. 4884-4900 ◽

Cited By ~ 47

Author(s):

Michelle T. Ma ◽

Levente K. Meszaros ◽

Brett M. Paterson ◽

David J. Berry ◽

Maggie S. Cooper ◽

...

Keyword(s):

Pet Imaging ◽

Ambient Conditions ◽

Desferrioxamine B

A tris(hydroxypyridinone) chelator coordinates the PET imaging isotope, 89Zr4+, rapidly and quantitatively under ambient conditions, but a 89Zr-labelled tris(hydroxypyridinone)-immunoconjugate is not stable to in vivo demetallation.

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