Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells

2010 ◽  
Vol 49 (4) ◽  
pp. 559-566 ◽  
Author(s):  
Pınar Erkekoğlu ◽  
Walid Rachidi ◽  
Viviana De Rosa ◽  
Belma Giray ◽  
Alain Favier ◽  
...  
Keyword(s):  
Protective Effect ◽  
Selenium Supplementation ◽  
Lncap Cells ◽  
Ethylhexyl Phthalate

Protective effect of D-psicose against testicular atrophy induced by di(2-ethylhexyl) phthalate

2013 ◽  
Vol 70 (4) ◽  
pp. 560-565 ◽  
Author(s):  
Shigeru Suna ◽  
Masaaki Tokuda ◽  
Tomohiro Hirao ◽  
Fuminori Yamaguchi ◽  
Nobuyuki Miyatake ◽  
...  
Keyword(s):  
Protective Effect ◽  
Testicular Atrophy ◽  
Ethylhexyl Phthalate

Protective effect of alpha-lipoic acid on di-(2-ethylhexyl) phthalate-induced testicular toxicity in mice

2020 ◽  
Vol 27 (12) ◽  
pp. 13670-13678 ◽  
Author(s):  
Mehdi Goudarzi ◽  
Mojtaba Haghi Karamallah ◽  
Alireza Malayeri ◽  
Mojtaba Kalantar ◽  
Esrafil Mansouri ◽  
...  
Keyword(s):  
Protective Effect ◽  
Lipoic Acid ◽  
Testicular Toxicity ◽  
Alpha Lipoic Acid ◽  
Ethylhexyl Phthalate

scholarly journals Hericium Erinaceus Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells

2020 ◽  
Vol 21 (6) ◽  
pp. 2138 ◽  
Author(s):  
Ines Amara ◽  
Maria Scuto ◽  
Agata Zappalà ◽  
Maria Laura Ontario ◽  
Antonio Petralia ◽  
...  
Keyword(s):  
Cell Death ◽  
Protective Effect ◽  
Pc12 Cells ◽  
Antioxidant Activities ◽  
Neuronal Cell Death ◽  
Neuronal Cell ◽  
Hericium Erinaceus ◽  
Nutritional Strategy ◽  
Induced Apoptosis ◽  
Ethylhexyl Phthalate

Hericium Erinaceus (HE) is a medicinal plant known to possess anticarcinogenic, antibiotic, and antioxidant activities. It has been shown to have a protective effect against ischemia-injury-induced neuronal cell death in rats. As an extending study, here we examined in pheochromocytoma 12 (PC12) cells, whether HE could exert a protective effect against oxidative stress and apoptosis induced by di(2-ethylhexyl)phthalate (DEHP), a plasticizer known to cause neurotoxicity. We demonstrated that pretreatment with HE significantly attenuated DEHP induced cell death. This protective effect may be attributed to its ability to reduce intracellular reactive oxygen species levels, preserving the activity of respiratory complexes and stabilizing the mitochondrial membrane potential. Additionally, HE pretreatment significantly modulated Nrf2 and Nrf2-dependent vitagenes expression, preventing the increase of pro-apoptotic and the decrease of anti-apoptotic markers. Collectively, our data provide evidence of new preventive nutritional strategy using HE against DEHP-induced apoptosis in PC12 cells.

scholarly journals Anti-oxidative and protective effect of soy tempeh on di(2-ethylhexyl)-phthalate (DEHP) injured FL83B mice liver cells

2018 ◽  
Vol 195 ◽  
pp. 012058
Author(s):  
Diana Lo ◽  
Reynetha DS Rawendra ◽  
Cian-Song Huang ◽  
Rupak Khatri-Chhetri ◽  
Yuh-Tai Wang ◽  
...  
Keyword(s):  
Protective Effect ◽  
Liver Cells ◽  
Mice Liver ◽  
Ethylhexyl Phthalate
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