Characterization and functional analysis of SMAD2 regulation in hair follicle cycle in Angora rabbits

Gene ◽  
2021 ◽  
Vol 770 ◽  
pp. 145339
Author(s):  
Zhiyuan Bao ◽  
Bohao Zhao ◽  
Shuaishuai Hu ◽  
Naisu Yang ◽  
Ming Liu ◽  
...  
2018 ◽  
Author(s):  
Marra I. Calvo-SSnchez ◽  
Elisa Carrasco ◽  
Sandra Fernnndez-Martos ◽  
Gema Moreno ◽  
Carmelo Bernabeu ◽  
...  

Cell Cycle ◽  
2021 ◽  
Vol 20 (2) ◽  
pp. 204-210
Author(s):  
Tao Ma ◽  
Jianyu Li ◽  
Jianping Li ◽  
Sufang Wu ◽  
Xiangba ◽  
...  

BMC Genomics ◽  
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Shanhe Wang ◽  
Wei Ge ◽  
Zhixin Luo ◽  
Yang Guo ◽  
Beilei Jiao ◽  
...  

2014 ◽  
Vol 161 ◽  
pp. 28-35 ◽  
Author(s):  
Wen L. Bai ◽  
Rong H. Yin ◽  
Rong L. Yin ◽  
Wu Q. Jiang ◽  
Jiao J. Wang ◽  
...  

2020 ◽  
Vol 6 (30) ◽  
pp. eaba1685 ◽  
Author(s):  
Shiqi Hu ◽  
Zhenhua Li ◽  
Halle Lutz ◽  
Ke Huang ◽  
Teng Su ◽  
...  

The progression in the hair follicle cycle from the telogen to the anagen phase is the key to regulating hair regrowth. Dermal papilla (DP) cells support hair growth and regulate the hair cycle. However, they gradually lose key inductive properties upon culture. DP cells can partially restore their capacity to promote hair regrowth after being subjected to spheroid culture. In this study, results revealed that DP spheroids are effective at inducing the progression of the hair follicle cycle from telogen to anagen compared with just DP cell or minoxidil treatment. Because of the importance of paracrine signaling in this process, secretome and exosomes were isolated from DP cell culture, and their therapeutic efficacies were investigated. We demonstrated that miR-218-5p was notably up-regulated in DP spheroid–derived exosomes. Western blot and immunofluorescence imaging were used to demonstrate that DP spheroid–derived exosomes up-regulated β-catenin, promoting the development of hair follicles.


2021 ◽  
Vol Volume 14 ◽  
pp. 527-539
Author(s):  
Xu Zhai ◽  
Meihua Gong ◽  
Yixuan Peng ◽  
Daping Yang

Sign in / Sign up

Export Citation Format

Share Document