ID: 3525300 VALUE OF REPEATED SERIAL PANCREATIC JUICE CYTOLOGIC EXAMINATION (SPACE) TO DIAGNOSE OF AN EARLY-STAGE PANCREATIC CAMCER IN THE FOLLOW-UP CASES WITH IRREGULAR STENOSIS OF MAIN PANCREATIC DUCT NEGATIVE FOR THE FIRST SPACE

2021 ◽  
Vol 93 (6) ◽  
pp. AB166
Author(s):  
Keiji Hanada ◽  
Akinori Shimizu ◽  
Keisuke Kurihara ◽  
Morito Ikeda ◽  
Yasuhiro Okuda ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Early Stage ◽  
Cytologic Examination ◽  
Irregular Stenosis

scholarly journals ON THE COLLECTION OF THE ENTIRE EXTERNAL SECRETION OF THE PANCREAS UNDER STERILE CONDITIONS AND THE FATAL EFFECT OF TOTAL LOSS OF PANCREATIC JUICE

1927 ◽  
Vol 45 (3) ◽  
pp. 561-570 ◽  
Author(s):  
Robert Elman ◽  
John M. McCaughan
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Total Loss ◽  
At Will

It has been possible by appropriate intubation of the main pancreatic duct of the dog to collect the total external secretion of the pancreas under sterile conditions. When all of the secretion is thus collected exitus occurs in a characteristic way in about a week with anorexia, gastric irritability, vomiting and asthenia. The significance of this finding has been briefly discussed. A method is also described for the "altercursive" intubation of the pancreas whereby the secretion may be collected or allowed to flow back to the duodenum at will.

Retortamonas intestinalis in the pancreatic juice of a patient with small nodular lesions of the main pancreatic duct

2001 ◽  
Vol 53 (4) ◽  
pp. 508-510 ◽  
Author(s):  
Osamu Kawamura ◽  
Youichi Kon ◽  
Atsushi Naganuma ◽  
Taku Iwami ◽  
Hideki Maruyama ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Nodular Lesions

scholarly journals Utility of “liquid biopsy” using pancreatic juice for early detection of pancreatic cancer

2018 ◽  
Vol 06 (12) ◽  
pp. E1454-E1461 ◽  
Author(s):  
Tetsuhiro Okada ◽  
Hirotoshi Iwano ◽  
Yusuke Ono ◽  
Hidenori Karasaki ◽  
Takayuki Sato ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Liquid Biopsy ◽  
Early Stage ◽  
Ductal Adenocarcinoma ◽  
Histological Evaluation ◽  
Resected Specimen ◽  
Driver Gene ◽  
Low Grade ◽  
Kras Mutations

Abstract Background Despite advances in the diagnosis of pancreatic ductal adenocarcinoma (PDA), histological evaluation of small and poorly defined masses in the pancreas is uncomfortable and unsafe. Methods We herein report a case of early stage PDA, in which multiple KRAS mutations were detected in the pancreatic juice preoperatively. A small hypoechoic area adjacent to the portal vein was detected through endoscopic ultrasound in the pancreatic body. KRAS mutations were evaluated using plasma, and the pancreatic juice by digital PCR. Results Pancreatic duct biopsy and pancreatic juice cytology were performed with no evidence of malignancy; however, KRAS mutations, KRAS G12V and G12D, were detected in the pancreatic juice. Histological assessment of the resected specimen demonstrated a solid tumor with desmoplastic reaction accompanied by carcinoma in situ in the main pancreatic duct where KRAS G12V mutation was identified. More detailed analysis demonstrated KRAS G12D mutation in the cluster of low grade pancreatic intraepithelial neoplasia, implying that the lesion developed independently. Conclusions Our study indicates the potential of “endoscopic liquid biopsy” to capture the driver gene for PDA diagnosis.

scholarly journals The Secretory Flow of Pancreatic Juice in the Main Pancreatic Duct: Visualization by Means of MRCP with Spatially Selective Inversion-Recovery Pulse

Radiology ◽  
2011 ◽  
Vol 261 (2) ◽  
pp. 582-586 ◽  
Author(s):  
Katsuyoshi Ito ◽  
Teruyuki Torigoe ◽  
Tsutomu Tamada ◽  
Koji Yoshida ◽  
Koichi Murakami ◽  
...  
Keyword(s):  
Pancreatic Duct ◽  
Pancreatic Juice ◽  
Main Pancreatic Duct ◽  
Inversion Recovery ◽  
Selective Inversion ◽  
Inversion Recovery Pulse

scholarly journals Postoperative Complications of Beger Procedure

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Nayana Samejima Peternelli ◽  
Tali Wajsfeld ◽  
Felipe Henrique Yazawa Santos ◽  
Otavio Schmidt de Azevedo ◽  
Rodrigo Altenfelder Silva ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Conservative Treatment ◽  
Pancreatic Duct ◽  
Main Pancreatic Duct ◽  
Pancreatic Head ◽  
Unusual Complication ◽  
Refractory Pain ◽  
Beger Procedure ◽  
Pancreaticojejunal Anastomosis

Introduction. Chronic pancreatitis (CP) is considered an inflammatory disease that may cause varying degrees of pancreatic dysfunction. Conservative and surgical treatment options are available depending on dysfunction severity.Presentation of Case. A 36-year-old male with history of heavy alcohol consumption and diagnosed CP underwent a duodenal-preserving pancreatic head resection (DPPHR or Beger procedure) after conservative treatment failure. Refractory pain was reported on follow-up three months after surgery and postoperative imaging uncovered stones within the main pancreatic duct and intestinal dilation. The patient was subsequently subjected to another surgical procedure and intraoperative findings included protein plugs within the main pancreatic duct and pancreaticojejunal anastomosis stricture. A V-shaped enlargement and main pancreatic duct dilation in addition to the reconstruction of the previous pancreaticojejunal anastomosis were performed. The patient recovered with no further postoperative complications in the follow-up at an outpatient clinic.Discussion. Main duct and pancreaticojejunal strictures are an unusual complication of the Beger procedure but were identified intraoperatively as the cause of patient’s refractory pain and explained intraductal protein plugs accumulation.Conclusion. Patients that undergo Beger procedures should receive close outpatient clinical follow-up in order to guarantee postoperative conservative treatment success and therefore guarantee an early detection of postoperative complications.

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