Control of oxidative stress and reduction in biochemical markers by Vitamin E treatment in patients with nonalcoholic steatohepatitis: a pilot study

2004 ◽  
Vol 29 (1) ◽  
pp. 39-41 ◽  
Author(s):  
M Kawanaka
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Pilot Study ◽  
Nonalcoholic Steatohepatitis ◽  
Biochemical Markers

Vitamin E treatment for patients with nonalcoholic steatohepatitis: Results of a pilot study

2003 ◽  
Vol 38 ◽  
pp. 203 ◽  
Author(s):  
F. Yakaryilmaz ◽  
S. Guliter ◽  
S. Ozenirler ◽  
G. Akyol
Keyword(s):  
Vitamin E ◽  
Pilot Study ◽  
Nonalcoholic Steatohepatitis

Supplementation of Vitamin E, Vitamin C, and Zinc Attenuates Oxidative Stress in Burned Children: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

2009 ◽  
Vol 30 (5) ◽  
pp. 859-866 ◽  
Author(s):  
Eliana Barbosa ◽  
Joel Faintuch ◽  
Emilia Addison Machado Moreira ◽  
Viviane Rodrigues Gonçalves da Silva ◽  
Maurício José Lopes Pereima ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Pilot Study ◽  
Vitamin C ◽  
Double Blind ◽  
Double Blind Placebo

A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis

2004 ◽  
Vol 2 (12) ◽  
pp. 1107-1115 ◽  
Author(s):  
Arun J. Sanyal ◽  
Pouneh S. Mofrad ◽  
Melissa J. Contos ◽  
Carol Sargeant ◽  
Velimir A. Luketic ◽  
...  
Keyword(s):  
Vitamin E ◽  
Pilot Study ◽  
Nonalcoholic Steatohepatitis

Nonalcoholic Fatty Liver Disease and Vitamin E - A Promising Relationship?

2019 ◽  
Vol 70 (1) ◽  
pp. 78-83
Author(s):  
Alexandra Totan ◽  
Daniela Gabriela Balan ◽  
Daniela Miricescu ◽  
Radu Radulescu ◽  
Iulia Ioana Stanescu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Therapeutic Potential ◽  
Plga Nanoparticles ◽  
Diet Group ◽  
Normal Diet ◽  
Oxidative Stress Biomarkers ◽  
Promising Alternative ◽  
Nonalcoholic Fatty Liver ◽  
High Caloric Diet

Oxidative stress (OS) plays an important role in NAFLD molecular mechanism. Nanoencapsulation represents a novel strategy to enhance therapeutic potential of conventional drugs. Our study analyses the encapsulated vitamin E effect on lipid metabolism and oxidative stress biomarkers in NAFLD rats. Animals were divided into 3 groups : G1 - the normal diet group; G2- the high caloric diet group ; G3 - high-caloric diet group receiving PLGA-vit E, 50 mg / kg. Serum advanced human oxidative protein (AOPP), total antioxidant capacity (TAC) and vitamin E were analysed using ELISA technique. Our results showed significant increase of G2 GPT, ALP, GGT, TG, glucose, TC and AOPP, versus G1 ( P [ 0.05) and a significant decrease of G2 serum TAC and vitamin E versus G1 results ( p = 0.01 and 0.01). Vitamin E nanoparticles (G3) caused a significant increase of TAC and significant decrease of serum AOPP, versus G2 (p [ 0.01). Results showed a significant reduction of GPT, GGT, ALP, TG and total cholesterol ( p [0.05) in G3 versus G2. PLGA nanoparticles should be considered an attractive and promising alternative to improve the bioavailability and biological activity of vitaminE.

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