The use of low-level electromagnetic fields to suppress atrial fibrillation

Heart Rhythm ◽  
2015 ◽  
Vol 12 (4) ◽  
pp. 809-817 ◽  
Author(s):  
Lilei Yu ◽  
John W. Dyer ◽  
Benjamin J. Scherlag ◽  
Stavros Stavrakis ◽  
Yong Sha ◽  
...  
2021 ◽  
Author(s):  
Daniel Sohinki ◽  
Joshua Thomas ◽  
Benjamin Scherlag ◽  
Stavros Stavrakis ◽  
Ali Yousif ◽  
...  

Author(s):  
Kanchan Kulkarni ◽  
Jagmeet P. Singh ◽  
Kimberly A. Parks ◽  
Demosthenes G. Katritsis ◽  
Stavros Stavrakis ◽  
...  

Background Low‐level tragus stimulation (LLTS) has been shown to significantly reduce atrial fibrillation (AF) burden in patients with paroxysmal AF. P‐wave alternans (PWA) is believed to be generated by the same substrate responsible for AF. Hence, PWA may serve as a marker in guiding LLTS therapy. We investigated the utility of PWA in guiding LLTS therapy in patients with AF. Methods and Results Twenty‐eight patients with AF were randomized to either active LLTS or sham (earlobe stimulation). LLTS was delivered through a transcutaneous electrical nerve stimulation device (pulse width 200 μs, frequency 20 Hz, amplitude 10–50 mA), for 1 hour daily over a 6‐month period. AF burden over 2‐week periods was assessed by noninvasive continuous ECG monitoring at baseline, 3 months, and 6 months. A 5‐minute control ECG for PWA analysis was recorded during all 3 follow‐up visits. Following the control ECG, an additional 5‐minute ECG was recorded during active LLTS in all patients. At baseline, acute LLTS led to a significant rise in PWA burden. However, active patients receiving chronic LLTS demonstrated a significant reduction in both PWA and AF burden after 6 months ( P <0.05). Active patients who demonstrated an increase in PWA burden with acute LLTS showed a significant drop in AF burden after 6 months of chronic LLTS. Conclusions Chronic, intermittent LLTS resulted in lower PWA and AF burden than did sham control stimulation. Our results support the use of PWA as a potential marker for guiding LLTS treatment of paroxysmal AF.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
B. Blake Levitt ◽  
Henry C. Lai ◽  
Albert M. Manville

Abstract Ambient levels of nonionizing electromagnetic fields (EMF) have risen sharply in the last five decades to become a ubiquitous, continuous, biologically active environmental pollutant, even in rural and remote areas. Many species of flora and fauna, because of unique physiologies and habitats, are sensitive to exogenous EMF in ways that surpass human reactivity. This can lead to complex endogenous reactions that are highly variable, largely unseen, and a possible contributing factor in species extinctions, sometimes localized. Non-human magnetoreception mechanisms are explored. Numerous studies across all frequencies and taxa indicate that current low-level anthropogenic EMF can have myriad adverse and synergistic effects, including on orientation and migration, food finding, reproduction, mating, nest and den building, territorial maintenance and defense, and on vitality, longevity and survivorship itself. Effects have been observed in mammals such as bats, cervids, cetaceans, and pinnipeds among others, and on birds, insects, amphibians, reptiles, microbes and many species of flora. Cyto- and geno-toxic effects have long been observed in laboratory research on animal models that can be extrapolated to wildlife. Unusual multi-system mechanisms can come into play with non-human species — including in aquatic environments — that rely on the Earth’s natural geomagnetic fields for critical life-sustaining information. Part 2 of this 3-part series includes four online supplement tables of effects seen in animals from both ELF and RFR at vanishingly low intensities. Taken as a whole, this indicates enough information to raise concerns about ambient exposures to nonionizing radiation at ecosystem levels. Wildlife loss is often unseen and undocumented until tipping points are reached. It is time to recognize ambient EMF as a novel form of pollution and develop rules at regulatory agencies that designate air as ‘habitat’ so EMF can be regulated like other pollutants. Long-term chronic low-level EMF exposure standards, which do not now exist, should be set accordingly for wildlife, and environmental laws should be strictly enforced — a subject explored in Part 3.


2020 ◽  
Vol 6 (3) ◽  
pp. 292-294
Author(s):  
Dingxin Qin ◽  
Jagmeet P. Singh

Radio Science ◽  
1982 ◽  
Vol 17 (5S) ◽  
pp. 149S-157S ◽  
Author(s):  
W. R. Adey ◽  
S. M. Bawin

2005 ◽  
Vol 43 (1) ◽  
pp. 142-149 ◽  
Author(s):  
M. Bachmann ◽  
J. Kalda ◽  
J. Lass ◽  
V. Tuulik ◽  
M. Säkki ◽  
...  

1986 ◽  
Vol 172 (2) ◽  
pp. 177-184 ◽  
Author(s):  
Maimon M. Cohen ◽  
Anna Kunska ◽  
Jacqueline A. Astemborski ◽  
Duncan McCulloch

2015 ◽  
Vol 179 ◽  
pp. 144-145 ◽  
Author(s):  
Mingxian Chen ◽  
Lilei Yu ◽  
Qiming Liu ◽  
Zhuo Wang ◽  
Songyun Wang ◽  
...  

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