AmTAR2: Functional characterization of a honeybee tyramine receptor stimulating adenylyl cyclase activity

2017 ◽  
Vol 80 ◽  
pp. 91-100 ◽  
Author(s):  
Tina Reim ◽  
Sabine Balfanz ◽  
Arnd Baumann ◽  
Wolfgang Blenau ◽  
Markus Thamm ◽  
...  
CHEST Journal ◽  
1995 ◽  
Vol 107 (5) ◽  
pp. 1420-1425 ◽  
Author(s):  
William B. Abernethy ◽  
John F. Butterworth ◽  
Richard C. Prielipp ◽  
Jian P. Leith ◽  
Gary P. Zaloga

Genetics ◽  
2002 ◽  
Vol 161 (1) ◽  
pp. 133-142 ◽  
Author(s):  
Celine Moorman ◽  
Ronald H A Plasterk

AbstractThe sgs-1 (suppressor of activated Gαs) gene encodes one of the four adenylyl cyclases in the nematode C. elegans and is most similar to mammalian adenylyl cyclase type IX. We isolated a complete loss-of-function mutation in sgs-1 and found it to result in animals with retarded development that arrest in variable larval stages. sgs-1 mutant animals exhibit lethargic movement and pharyngeal pumping and (while not reaching adulthood) have a mean life span that is >50% extended compared to wild type. An extensive set of reduction-of-function mutations in sgs-1 was isolated in a screen for suppressors of a neuronal degeneration phenotype induced by the expression of a constitutively active version of the heterotrimeric Gαs subunit of C. elegans. Although most of these mutations change conserved residues within the catalytic domains of sgs-1, mutations in the less-conserved transmembrane domains are also found. The sgs-1 reduction-of-function mutants are viable and have reduced locomotion rates, but do not show defects in pharyngeal pumping or life span.


Neuron ◽  
1999 ◽  
Vol 23 (4) ◽  
pp. 787-798 ◽  
Author(s):  
Scott T Wong ◽  
Jaime Athos ◽  
Xavier A Figueroa ◽  
Victor V Pineda ◽  
Michele L Schaefer ◽  
...  

2008 ◽  
Vol 381 (1) ◽  
pp. 86-93 ◽  
Author(s):  
Corinna M. Spangler ◽  
Christian Spangler ◽  
Martin Göttle ◽  
Yuequan Shen ◽  
Wei-Jen Tang ◽  
...  

FEBS Letters ◽  
1995 ◽  
Vol 361 (1) ◽  
pp. 70-74 ◽  
Author(s):  
Tomer Avidor-Reiss ◽  
Renata Zippel ◽  
Rivka Levy ◽  
Danielle Saya ◽  
Vittoria Ezra ◽  
...  

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