Ruthenium(II) complexes of 2,2′-bipyridine-5,5′-dicarboxylic acid: Synthesis, structure, DNA binding, cytotoxicity and antioxidant activity

2013 ◽  
Vol 404 ◽  
pp. 58-67 ◽  
Author(s):  
Thangavel Sathiya Kamatchi ◽  
Nataraj Chitrapriya ◽  
V.S. Jamal Ahamed ◽  
Surk-Sik Moon ◽  
Frank R. Fronczek ◽  
...  
MedChemComm ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 1679-1697 ◽  
Author(s):  
Katarina Jakovljević ◽  
Milan D. Joksović ◽  
Ivana Z. Matić ◽  
Nina Petrović ◽  
Tatjana Stanojković ◽  
...  

1,3,4-Thiadiazole compounds containing catechol moiety and chalcone motif are synthesized and examined for antioxidant activity, cytotoxicity and DNA-binding activity.


2020 ◽  
Vol 36 (05) ◽  
pp. 834-842
Author(s):  
Rezan Ali Saleh ◽  
Hikmat Ali Mohammad ◽  
Salim Najm Aldin Saber

The mixing of one mole of 2,2'-bipyridine-3,3'-dicarboxylic acid (bpdc) with two mole of potassium hydroxide (KOH) in methanol were refluxed for (half hour), followed by addition of one mole methanol solution of MCl2.nH2O (where M=Co, Ni or Cu). The mixture was refluxed for (2 hours) to give colored complexes of the metal ions of [M(bpdc)(H2O)4]. The [M(bpdc)(H2O)4] were reacted with one mole of 2-Mercapto-5-phenyl-1,3,4-oxadiazole (phozSH) producing the colored mixed ligand complexes with general formula [M(bpdc)(phozSH)(H2O)3] in which the metal ions coordinated to the ligand through O-atoms of carboxyl group in (bpdc) and N-atom of (phozSH) ligand. The ligands and complexes are well identified by using Furrier transform infrared spectroscopy, 1H-NMR, 13C-NMR, Electronic spectroscopy, CHNS analysis, Melting point, conductivity measurement. The Antioxidant activity were screened for all the complexes by the use of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method.


2010 ◽  
Vol 8 (19) ◽  
pp. 4297 ◽  
Author(s):  
Noor-ul H. Khan ◽  
Nirali Pandya ◽  
Manoj Kumar ◽  
Prasanta Kumar Bera ◽  
Rukhsana I. Kureshy ◽  
...  

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