Aeolian driven silicate comminution unlikely to be responsible for the rapid loss of Martian methane

SummaryThe effects of trypsin and plasmin on the functional and physicochemical properties of purified human fibrinogen were observed at various stages of proteolysis. Concentrations of plasmin and trypsin that produced fibrinogenolysis at comparable rates as measured in a pH stat produced, at similar rates, loss of precipitability of fibrinogen by heat and ammonium sulphate and alterations in electrophoretic mobility on starch gel. Trypsin produced a more rapid loss of clottability of fibrinogen and a more rapid appearance of inhibitors of the thrombin-fibrinogen clotting system than did plasmin. Consistent differences were noted between the effects of trypsin and plasmin on the immunoelectrophoretic properties of fibrinogen during the early stages of proteolysis.These results are consistent with the hypothesis that trypsin initially reacts with the same peptide bonds of fibrinogen that are split by thrombin, but these same bonds do not appear to be split initially by plasmin. Measurement of the various functional and physico-chemical changes produced by the action of trypsin and plasmin on fibrinogen can be used to recognize various stages of proteolysis.

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Heparin, Protamine and Polybrene

Thrombosis and Haemostasis ◽

10.1055/s-0038-1656300 ◽

1965 ◽

Vol 13 (02) ◽

pp. 550-560 ◽

Cited By ~ 2

Author(s):

Anthony Britten

Keyword(s):

Factor Viii ◽

Incubation Mixture ◽

Factor V ◽

Factor Viii Activity ◽

Rapid Loss

SummaryThe effects of incubating heparin, protamine or Polybrene with plasma were studied. All three drugs cause rapid loss of factor V from decalcified plasma, while Polybrene also accelerates the loss of factor VIII activity. These changes are related to temperature, the period of incubation and the dose of the drug used, and can be partially prevented by inclusion of neutralizing doses of the appropriate antagonist in the incubation mixture.The implications of these findings are discussed.

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A single infusion of Zoledronic Acid after terminating treatment with Denosumab prevents rebound-fractures and rapid loss of bone mineral densitiy in most, but not all patients treated for Osteoporosis

10.1055/s-0039-1679969 ◽

2019 ◽

Author(s):

T Lehmann ◽

J Everts

Keyword(s):

Zoledronic Acid ◽

Bone Mineral ◽

Rapid Loss ◽

Single Infusion

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Diagnostic approach to causes of spinal pain

NATIONAL JOURNAL OF NEUROLOGY ◽

10.28942/nnj.v1i5.113 ◽

2018 ◽

pp. 66-70

Author(s):

F. D. Nasirova

Keyword(s):

Spinal Pain ◽

Rapid Loss ◽

Loss Of Weight ◽

History Of ◽

Radiologic Investigation ◽

Males And Females ◽

Serious Disease ◽

Pain At Rest ◽

Oncologic Diseases ◽

Selection Of

Causes of spinal pain are extremely varying. Sex composition of patients referring with spinal pain at the age of 16 to 35 was 35% and 65% for males and females, respectively. Peak number of complaints was observed in 30-40 years age group of highest work ability. The followings should be considered as precautions in spinal pain: onset of pain at the age of 20 and after 50, family history of oncologic diseases, walking disorders or dysfunctions of sphincters, numbness in extremities, general malaise and rapid loss of weight, pain at rest and primarily at night, as these conditions may be a warning of underlying serious disease. Selection of algorithm for radiologic investigation is decided by the treating physician.

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Faculty Opinions recommendation of Experimental warming causes rapid loss of plant diversity in New England salt marshes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2000966.1568066 ◽

2010 ◽

Author(s):

Joseph Craine

Keyword(s):

New England ◽

Plant Diversity ◽

Salt Marshes ◽

Experimental Warming ◽

Rapid Loss

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Faculty Opinions recommendation of ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718319725.793492560 ◽

2014 ◽

Author(s):

Marian Waterman

Keyword(s):

Er Stress ◽

Unfolded Protein Response ◽

Intestinal Epithelial ◽

Rapid Loss ◽

Unfolded Protein ◽

The Unfolded Protein Response ◽

Protein Response

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Modification of Wood with Monoethanolamino-borate by The Data of X-Ray Photoelectron Spectroscopy

MATEC Web of Conferences ◽

10.1051/matecconf/201819604005 ◽

2018 ◽

Vol 196 ◽

pp. 04005

Author(s):

Irina Stepina ◽

Irina Kotlyarova

Keyword(s):

Particle Size ◽

Photoelectron Spectroscopy ◽

Model Compound ◽

Hydrolytic Stability ◽

Photoelectron Spectra ◽

Wood Cellulose ◽

Rapid Loss ◽

X Ray ◽

Wood Protection ◽

Cellulose Materials

The difficulty of wood protection from biocorrosion and fire is due to the fact that modifiers in use are washed out from the surface of the substrate under the influence of environmental factors. This results in a rapid loss of the protective effect and other practically important wood characteristics caused by the modification. To solve this problem is the aim of our work. Here, monoethanolaminoborate is used as a modifier, where electron-donating nitrogen atom provides a coordination number equal to four to a boron atom, which determines the hydrolytic stability of the compounds formed. Alpha-cellulose ground mechanically to a particle size of 1 mm at most was used as a model compound for the modification. X-ray photoelectron spectra were recorded on the XSAM-800 spectrometer (Kratos, UK). Prolonged extraction of the modified samples preceded the registration of the photoelectron spectra to exclude the fixation of the modifier molecules unreacted with cellulose. As a result of the experiment, boron and nitrogen atoms were found in the modified substrate, which indicated the hydrolytic stability of the bonds formed between the modifier molecules and the substrate. Therefore monoethanolaminoborate can be considered as a non-extractable modifier for wood-cellulose materials.

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Myocardial extraction and retention of 2-iododesmethylimipramine: a novel flow marker

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1986.250.6.h1060 ◽

1986 ◽

Vol 250 (6) ◽

pp. H1060-H1070 ◽

Cited By ~ 4

Author(s):

S. E. Little ◽

J. M. Link ◽

K. A. Krohn ◽

J. B. Bassingthwaighte

Keyword(s):

Escape Rate ◽

Flow Imaging ◽

Rapid Loss ◽

Ideal Flow ◽

Regional Flow ◽

Myocardial Flow

An ideal deposition marker for measuring regional flow is completely extracted during transcapillary passage and permanently retained. beta-Labeled desmethylimipramine ([3H]DMI) is a nearly ideal flow marker. To obtain gamma- and positron-emitting markers, DMI was iodinated to form 2-iododesmethylimipramine (IDMI). IDMI was more lipophilic than DMI. In isolated saline-perfused rabbit hearts its transorgan extraction was greater than 99%; and retention was greater than 98% at 5 min at mean flows of up to 3.5 ml X g-1 X min-1. During washout, the fractional escape rate was less than 0.1% X min-1 and was independent of flow. In isolated blood-perfused rabbit hearts, extraction was still 98%, but retention was as low as 86% after 5 min at a flow of 1.6 ml X g-1 X min-1. The fractional escape rate was up to 2% X min-1 but independent of flow. Despite this relatively rapid loss, regional IDMI deposition remains proportional to regional flow for many minutes. Therefore IDMI is useful as an externally detectable "molecular microsphere" for myocardial flow imaging in vivo.

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Knowledge-guided multiobjective particle swarm optimization with fusion learning strategies

Complex & Intelligent Systems ◽

10.1007/s40747-020-00263-z ◽

2021 ◽

Author(s):

Wei Li ◽

Xiang Meng ◽

Ying Huang ◽

Soroosh Mahmoodi

Keyword(s):

Particle Swarm Optimization ◽

Learning Strategies ◽

Learning Strategy ◽

Particle Swarm ◽

Population Diversity ◽

Selection Strategy ◽

Rapid Loss ◽

Solution Quality ◽

Swarm Optimization ◽

Multiobjective Particle Swarm Optimization

AbstractMultiobjective particle swarm optimization (MOPSO) algorithm faces the difficulty of prematurity and insufficient diversity due to the selection of inappropriate leaders and inefficient evolution strategies. Therefore, to circumvent the rapid loss of population diversity and premature convergence in MOPSO, this paper proposes a knowledge-guided multiobjective particle swarm optimization using fusion learning strategies (KGMOPSO), in which an improved leadership selection strategy based on knowledge utilization is presented to select the appropriate global leader for improving the convergence ability of the algorithm. Furthermore, the similarity between different individuals is dynamically measured to detect the diversity of the current population, and a diversity-enhanced learning strategy is proposed to prevent the rapid loss of population diversity. Additionally, a maximum and minimum crowding distance strategy is employed to obtain excellent nondominated solutions. The proposed KGMOPSO algorithm is evaluated by comparisons with the existing state-of-the-art multiobjective optimization algorithms on the ZDT and DTLZ test instances. Experimental results illustrate that KGMOPSO is superior to other multiobjective algorithms with regard to solution quality and diversity maintenance.

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