Inverse relationship between raft LRP1 localization and non-raft ERK1,2/MMP9 activation in idiopathic dilated cardiomyopathy: Potential impact in ventricular remodeling

2014 ◽  
Vol 176 (3) ◽  
pp. 805-814 ◽  
Author(s):  
Santiago Roura ◽  
Roi Cal ◽  
Carolina Gálvez-Montón ◽  
Elena Revuelta-Lopez ◽  
Laura Nasarre ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Inverse Relationship ◽  
Ventricular Remodeling ◽  
Idiopathic Dilated Cardiomyopathy ◽  
Potential Impact ◽  
Mmp9 Activation

scholarly journals Survival and echocardiographic evaluation of dogs with idiopathic dilated cardiomyopathy treated with carvedilol

2010 ◽  
Vol 62 (3) ◽  
pp. 555-563 ◽  
Author(s):  
E.C. Soares ◽  
G.G. Pereira ◽  
L.C. Petrus ◽  
M. Leomil Neto ◽  
F.L. Yamaki ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Ventricular Remodeling ◽  
Left Ventricular ◽  
Idiopathic Dilated Cardiomyopathy ◽  
P Value ◽  
Echocardiographic Evaluation ◽  
Before And After ◽  
Group A ◽  
The Stability ◽  
Group B

Sixty dogs with idiopathic dilated cardiomyopathy were randomly treated with traditional therapy - digitalis, diuretics, angiotensin-converting inhibitors - (group A) or treated with these drugs plus carvedilol (group B). Echocardiographic variables were measured before and after 3, 13, 26, and 52 weeks of treatment or until death. Comparisons between groups and time were performed. No significant differences between groups were found in the most of the echocardiographic variables. The left ventricular end-systolic diameter indexed to body surface area (LVESDi) increased significantly in the group A dogs compared to the group B animals. The survival of groups A and B dogs were not different (P-value=0.1137). In conclusion, the stability of the LVESDi observed in the group treated with carvedilol may represent the beneficial effect over the ventricular remodeling.

scholarly journals Ventricular Remodeling and Survival Are More Favorable for Myocarditis Than For Idiopathic Dilated Cardiomyopathy in Childhood

2010 ◽  
Vol 3 (6) ◽  
pp. 689-697 ◽  
Author(s):  
Susan R. Foerster ◽  
Charles E. Canter ◽  
Amy Cinar ◽  
Lynn A. Sleeper ◽  
Steven A. Webber ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Ventricular Remodeling ◽  
Idiopathic Dilated Cardiomyopathy
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